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Olen nõus

Ildar Nisamedtinov

https://etis.ee/CV/Ildar_Nisamedtinov/est
7.10.1976
56654 989
inisamedtinov@lallemand.com
http://lallemand.com

Teenistuskäik

Töökohad ja ametid
01.01.2019–...   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, Vanemlektor (0,50)
01.02.2016–...   
Lallemand, Inc., Vice president, coorporate R&D coordination (1,00)
01.01.2018–31.12.2018   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, sihtrahastusega vanemteadur (0,50)
01.01.2017–31.12.2017   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, Vanemteadur (0,50)
01.01.2013–31.12.2016   
Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond, Toiduainete instituut, Toidutehnoloogia õppetool, Vanemteadur (0,50)
01.09.2007–31.12.2012   
Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond, Dotsent (0,50)
01.11.2004–2007   
AS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus, Projektijuht (0,75)
2002–2004   
Salutaguse Pärmitehas AS, specialty project engineer (1,00)
 
 
Haridustee
1994-1999 TTÜ Bio- ja Toiduainete Tehnoloogia, bakalaureus1999-2001 magister, TTÜ Bio- ja Toiduainete Tehnoloogia
1999-2001 MSc, TUT, Biotechnology and Food Technology
2002–2006   
PhD, loodusteadused
2002–2006   
2002-2006 doktorant, TTÜ Bio- ja Toiduainete Tehnoloogia
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
Eesti Mikrobioloogide Seltsi Liige
 
 
Loometöö
Mikroorganismide ainevahetus, toidu - ja biotehnoloogilised protsessid mikroorganismide osavõtul.
 
 
Lisainfo
Õpetatavad ained:
1. Toidu biotehnoloogia
2. Fermentatsiooniprotsessid toidutööstuses

Kvalifikatsioon

Teaduskraadid
Ildar Nisamedtinov, doktorikraad, 2006, (juh) Toomas Paalme, ¹³C- ja fluoressentsmärgise kasutamine Saccharomyces spp. ainevahetuse uurimisel, Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond, Toiduainete instituut.
 
 
Teaduspreemiad ja tunnustused
2002, Ildar Nisamedtinov, puuduvad
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); TÄPSUSTUS: Mikroobide ainevahetus
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.2. Mikrobioloogia
 
 
Lisainfo
Bakalaureus
Magister
TTÜ, 1999
TTÜ, 2001

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2020
Rosend, J.; Kaleda, A.; Kuldjärv, R.; Arju, G.; Nisamedtinov, I. (2020). The effect of apple juice clarification and concentration on cider fermentation and properties of the final product. Foods, 9, 1401. DOI: 10.3390/foods9101401.
1.1.
2019
Rosend, J.; Kuldjärv, R.; Arju, G.; Nisamedtinov, I. (2019). Yeast performance characterisation in different cider fermentation matrices. Agronomy Research, 17 (5), 2040−2053. DOI: 10.15159/AR.19.178.
1.1.
2017
Paalme, T.; Vilbaste, A.; Kevvai, K.; Nisamedtinov, I.; Hälvin-Tanilas, K. (2017). Assessment of bioavailable B vitamin content in food using in vitro digestibility assay and LC-MS SIDA. Analytical and Bioanalytical Chemistry, 409 (27), 6475−6484. DOI: 10.1007/s00216-017-0592-3.
1.1.
2016
Kevvai, K.; Kütt, M.-L.; Nisamedtinov, I.; Paalme, T. (2016). Simultaneous utilization of ammonia, free amino acids and peptides during fermentative growth of Saccharomyces cerevisiae. Asymmetric Michael Addition of an Alanine Derivative, 122 (1), 110−115. DOI: 10.1002/jib.298.
1.1.
2014
Kevvai, K.; Kütt, M.-L.; Nisamedtinov, I.; Paalme, T. (2014). Utilization of N-15-labelled yeast hydrolysate in Lactococcus lactis IL1403 culture indicates co-consumption of peptide-bound and free amino acids with simultaneous efflux of free amino acids. Antonie van Leeuwenhoek, 105 (3), 511−522. DOI: 10.1007/s10482-013-0103-2.
1.1.
2014
Hälvin, K., Nisamedtinov, I., & Paalme, T. (2014). Comparison of different extraction methods to determine free and bound forms of B-group vitamins in quinoa. Analytical and Bioanalytical Chemistry, 406 (28), 7355−7366. DOI: 10.1007/s00216-014-8122-z.
1.1.
2014
Paalme, T.; Kevvai, K.; Vilbaste, A.; Haelvin, K.; Nisamedtinov, I. (2014). Uptake and accumulation of B-group vitamers in Saccharomyces cerevisiae in ethanol-stat fed-batch culture. World Journal of Microbiology and Biotechnology, 30 (9), 2351−2359. DOI: 10.1007/s11274-014-1660-x.
1.1.
2013
Hälvin, K.; Paalme, T.; Nisamedtinov, I. (2013). Comparison of different extraction methods for simultaneous determination of B-complex vitamins in nutritional yeast using LC/MS-TOF and stable isotope dilution assay. Analytical and Bioanalytical Chemistry, 405 (4), 1213−1222. DOI: 10.1007/s00216-012-6538-x.
1.1.
2013
Mihhalevski, Anna; Nisamedtinov, Ildar; Hälvin, Kristel; Ošeka, Aleksandra; Paalme, Toomas (2013). Stability of B-complex vitamins and dietary fiber during rye sourdough bread production. Journal of Cereal Science, 57 (1), 30−38. DOI: 10.1016/j.jcs.2012.09.007.
1.1.
2012
Orumets, Kerti; Kevvai, Kaspar; Nisamedtinov, I; Tamm, T; Paalme, T. (2012). YAP1 over‐expression in Saccharomyces cerevisiae enhances glutathione accumulation at its biosynthesis and substrate availability levels. Biotechnology Journal, 7 (4), 566−568. DOI: 10.1002/biot.201100363.
5.2.
2012
Hälvin, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2012). Limitations of LC-MS in B-complex vitamins determination. 2nd International Vitamin Conference: 2nd International Vitamin Conference, Copenhagen (Denmark) 23-25 May 2012. Copenhagen: DTU Food National Food Institute.
5.2.
2012
Hälvin, Kristel; Mihhalevski, Anna; Nisamedtinov, Ildar; Ošeka, Aleksandra; Paalme, Toomas (2012). Determination of B-complex vitamins’ stability during rye sourdough breads production using LC-MS and stable isotope dilution assay. Clinical Chemistry and Laboratory Medicine, 50: Advances and Controversies in B-Vitamins and Choline, Leipzig (Germany) 5-8 March 2012. Ed. Mario Plebani. Germany: Walter de Gruyter & Co, A57−A57.
1.1.
2011
Kaseleht, K., Paalme, T., Nisamedtinov, I. (2011). Quantitative Analysis of Acetaldehyde in Foods Consumed by Children using SPME/GC-MS(Tof), On-fiber Derivatization and Deuterated Acetaldehyde as an Internal Standard. Agronomy Research, 9 (2), 395−401.
1.1.
2011
Nisamedtinov, I.; Kevvai, K.; Orumets, K.; Arike, L.; Sarand, I.; Korhola, M.; Paalme, T. (2011). Metabolic changes underlying the higher accumulation of glutathione in Saccharomyces cerevisiae mutants. Applied Microbiology and Biotechnology, 89 (4), 1029−1037. DOI: 10.1007/s00253-010-2946-z.
1.1.
2010
Nisamedtinov, I.; Kevvai, K.; Orumets, K.; Rautio, J.; Paalme, T. (2010). Glutathione accumulation in ethanol-stat fed-batch culture of Saccharomyces cerevisiae with a switch to cysteine feeding. Applied Microbiology and Biotechnology, 87 (1), 175−183. DOI: 10.1007/s00253-010-2502-x.
1.3.
2010
Nisamedtinov, Ildar; Orumets, Kerti; Kevvai, Kaspar; Viiard, Ene; Sarand, Inga; Paalme, Toomas (2010). Multilevel Control of GSH Accumulation in Mutant and Wild-Type Strains of S. cerevisiae Under Conditions of Smooth Cysteine Addition. Chemical Engineering Transactions: IBIC 2010 2nd International Conference on Industrial Biotechnology. Ed. Enrico Bardone, Aurelio Viglia., 91−96. DOI: 10.3303/CET1020016.
3.5.
2010
Hälvin, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2010). Simultaneous quantification of the B-complex vitamins in dried yeast using UPLC-MS and isotope labeled internal standards. Food and Nutrition: FoodBalt 2010 Tallinn 29. - 30. October 2010. Tallinn: Tallinn University of Technology, 93−93. (XVII).
5.2.
2010
Hälvin, Kristel; Ošeka, Aleksandra; Tammel, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2010). Effect of hydrolytic enzymes on simultaneous analysis of the B-complex vitamin content in dry yeast using LC-MS and isotope labeled internal standards. 1st International Vitamin Conference: 1st International Vitamin Conference, Copenhagen 19-21 Mai 2010. DTU Food National Food Institute.
2.3.
2009
Nisamedtinov, I. (2009). 13C and fluorescence labeling in yeast metabolic studies: Visualizing the time-spatial structure of metabolic network and determination of stress status in the cells. (Tallinna Tehnikaülikool). LAP LAMBERT Academic Publishing.
1.1.
2008
Nisamedtinov, I.; Lindsey, G. G.; Karreman, R.; Orumets, K.; Koplimaa, M.; Kevvai, K.; Paalme, T. (2008). The response of the yeast Saccharomyces cerevisiae to sudden vs. gradual changes in environmental stress monitored by expression of the stress response protein Hsp12p. FEMS Yeast Research, 8 (6), 829−838. DOI: 10.1111/j.1567-1364.2008.00391.x.
1.1.
2007
Kasemets K., Nisamedtinov I., Laht T.-M.,Abner K., Paalme T. (2007). Growth characteristics of Saccharomyces cerevisiae S288C in changing environmental conditions: auxo-accelerostat study. Antonie van Leeuwenhoek, 92 (1), 109−128. DOI: 10.1007/s10482-007-9141-y.
5.2.
2007
Nisamedtinov, I.; Lindsey, R.; Karreman, R.; Orumets, K.; Koplimaa, M.; Kevvai, K.; Paalme, T. (2007). The study of static and dynamic environmental stress of Saccharomyces cerevisiae using heat shock protein Hsp12p-Gfp2p construct. Physiology of Yeasts and Filamentous Fungi PYFF3: 3rd European Federation of Biotechnology Conference, Helsinki (Finland), June 13–16, 2007. Ed. Kuokka-Ihalainen, A.; Saloheimo, M.; Pakula, T. Helsingi: VTT Technical Research Centre of Finland, 70. (VTT Symposium ; 245).
5.2.
2007
Orumets, K.; Nisamedtinov, I.; Koplimaa, M.; Paalme, T. (2007). Effect of different stressful conditions on the expression of HSP12P-GFP2 fusion protein in Saccharomyces cerevisiae. FoodBalt-2007: 2nd Baltic Conference on Food Science and Technology, Kaunas, June 13-14 2007. Technologija, 27.
1.1.
2006
Paalme, Toomas; Nisamedtinov, Ildar; Abner, Kristo; Laht, Tiiu-Maie; Drews, Monika; Pehk, Tõnis (2006). Application of  <SUP>13</SUP>C-[2]- and <SUP>13</SUP>C[1,2] acetate in metabolic labelling studies of yeast and insect cells. Antonie van Leeuwenhoek, 89, 443−457. DOI: 10.1007/s10482-005-9053-7.
2.3.
2006
Nisamedtinov, I. (2006). 13C- ja fluoressentsmärgise kasutamine Saccharomyces spp. ainevahetuse uurimisel. (Doktoritöö, Tallinna Tehnikaülikool). Tallinn: Tallinn University of Technology Press.
3.1.
2006
Kasemets, K.; Nisamedtinov, I.; Abner, K.; Paalme, T. (2006). The study of the fermentative growth of Saccharomyces cerevisiae S288C using auxo-accelerostat technique. In: Mendez-Vilas, A. (Ed.). Modern Multidisciplinary Applied Microbiology. Exploiting Microbes and Their Interactions (756−760). . Wiley-VCH.
3.1.
2006
Kasemets, K. Nisamedtinov, I., Abner, K. And Paalme, T. (2006). Study of the fermentative growth of S. Cerevisiae S288C using auxo-accelerostat technique. In: Mendez-Vilas, A (Ed.). Modern Multidisciplinary Applied Microbiology. Exploiting Microbes and Their Interaction. (756−762). . Wiley-VCH.
3.4.
2006
Nisamedtinov, I.; Lindsley, G.; Karreman, R.; Orumets, K.; Koplimaa, M.; Paalme, T. (2006). Effect of slowly increasing temperature and NaCl concentration on the expression of Hsp12-GFP2 fusion protein in Saccharomyces cerevisisae: an auxo-accelerostat study. In: Solvary, S; Toldi, O. (Ed.). FinMed 2006, 2nd International Conference on Bioreactor Technology in Cell, Tissue Culture and Biomedical Applications (102−112). . BioBien Innovations (BBi).
1.1.
2003
Kasemets, K.; Drews, M.; Nisamedtinov, I.; Adamberg, K.; Paalme, T (2003). Modification of A-stat for the characterization of microorganisms. Journal of Microbiological Methods, 55 (1), 187−200.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quasi-steady-state cultures. International Congress on Bioreactor Technology in Cell-, Tissue Culture and Biomedical Applications, 1st, Tampere, Finland 14 - 18 July 2003. Ed. Sorvari, S. BioBien Innovations (BBi), 218−225.
1.3.
1998
Drews, M.; Kasemets, K.; Nisamedtinov, I.; Paalme, T. (1998). Continuous cultivation of insect and yeast cells at maximum specific growth rate. Proceedings of the Estonian Academy of Sciences. Chemistry, 47, 175−188.

Tööstusomand

30.09.2020

Ildar Nisamedtinov

https://etis.ee/CV/Ildar_Nisamedtinov/eng
7.10.1976
56654 989
inisamedtinov@lallemand.com

Career

Institutions and positions
01.01.2019–...   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Senior Lecturer (0,50)
01.02.2016–...   
Lallemand, Inc., Vice president, coorporate R&D coordination (1,00)
01.01.2018–31.12.2018   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Senior Researcher (0,50)
01.01.2017–31.12.2017   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Senior Researcher (0,50)
01.01.2013–31.12.2016   
Tallinn University of Technology , Faculty of Chemical and Materials Technology, Department of Food Processing, Chair of Food Technology, Senior Researcher (0,50)
01.09.2007–31.12.2012   
Tallinn University of Technology , Faculty of Chemical and Materials Technology, Associate Professor (0,50)
01.11.2004–2007   
Center of Food and Fermentation Technologies, Project leader (0,75)
2002–2004   
Salutaguse Yeast Factory, specialty project engineer (1,00)
 
 
Education
1994-1999 TUT, Biotechnology and Food Technology, bachelor
1999-2001 MSc, TUT, Biotechnology and Food Technology
2002–2006   
PhD, natural sciences
2002–2006   
2002-2006 PhD student, Biotechnology and Food Technology
 
 
R&D related managerial and administrative work
Member of Estonian Society of Microbiologists
 
 
Creative work
Microbial metabolism, food- and biotechnological processes with microorganisms.
 
 
Additional information
Courses:
1. Food biotechnology
2. Fermentation processes in food industry

Qualifications

Academic degrees
Ildar Nisamedtinov, Doctor's Degree, 2006, (sup) Toomas Paalme, ¹³C- ja fluoressentsmärgise kasutamine Saccharomyces spp. ainevahetuse uurimisel (Application of 13C and fluorescence labeling in metabolic studies of Saccharomyces spp.), Tallinn University of Technology Faculty of Chemical and Materials Technology, Department of Food Processing.
 
 
Honours & awards
2002, Ildar Nisamedtinov, puuduvad
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; SPECIFICATION: Microbial metabolism
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.2. Microbiology; SPECIFICATION: Yeast stress responses, yeast as a cell factory
 
 
Additional information
Bachelor
MSc
TUT, 1999
TUT, 2001

Projects in progress

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2020
Rosend, J.; Kaleda, A.; Kuldjärv, R.; Arju, G.; Nisamedtinov, I. (2020). The effect of apple juice clarification and concentration on cider fermentation and properties of the final product. Foods, 9, 1401. DOI: 10.3390/foods9101401.
1.1.
2019
Rosend, J.; Kuldjärv, R.; Arju, G.; Nisamedtinov, I. (2019). Yeast performance characterisation in different cider fermentation matrices. Agronomy Research, 17 (5), 2040−2053. DOI: 10.15159/AR.19.178.
1.1.
2017
Paalme, T.; Vilbaste, A.; Kevvai, K.; Nisamedtinov, I.; Hälvin-Tanilas, K. (2017). Assessment of bioavailable B vitamin content in food using in vitro digestibility assay and LC-MS SIDA. Analytical and Bioanalytical Chemistry, 409 (27), 6475−6484. DOI: 10.1007/s00216-017-0592-3.
1.1.
2016
Kevvai, K.; Kütt, M.-L.; Nisamedtinov, I.; Paalme, T. (2016). Simultaneous utilization of ammonia, free amino acids and peptides during fermentative growth of Saccharomyces cerevisiae. Asymmetric Michael Addition of an Alanine Derivative, 122 (1), 110−115. DOI: 10.1002/jib.298.
1.1.
2014
Kevvai, K.; Kütt, M.-L.; Nisamedtinov, I.; Paalme, T. (2014). Utilization of N-15-labelled yeast hydrolysate in Lactococcus lactis IL1403 culture indicates co-consumption of peptide-bound and free amino acids with simultaneous efflux of free amino acids. Antonie van Leeuwenhoek, 105 (3), 511−522. DOI: 10.1007/s10482-013-0103-2.
1.1.
2014
Hälvin, K., Nisamedtinov, I., & Paalme, T. (2014). Comparison of different extraction methods to determine free and bound forms of B-group vitamins in quinoa. Analytical and Bioanalytical Chemistry, 406 (28), 7355−7366. DOI: 10.1007/s00216-014-8122-z.
1.1.
2014
Paalme, T.; Kevvai, K.; Vilbaste, A.; Haelvin, K.; Nisamedtinov, I. (2014). Uptake and accumulation of B-group vitamers in Saccharomyces cerevisiae in ethanol-stat fed-batch culture. World Journal of Microbiology and Biotechnology, 30 (9), 2351−2359. DOI: 10.1007/s11274-014-1660-x.
1.1.
2013
Hälvin, K.; Paalme, T.; Nisamedtinov, I. (2013). Comparison of different extraction methods for simultaneous determination of B-complex vitamins in nutritional yeast using LC/MS-TOF and stable isotope dilution assay. Analytical and Bioanalytical Chemistry, 405 (4), 1213−1222. DOI: 10.1007/s00216-012-6538-x.
1.1.
2013
Mihhalevski, Anna; Nisamedtinov, Ildar; Hälvin, Kristel; Ošeka, Aleksandra; Paalme, Toomas (2013). Stability of B-complex vitamins and dietary fiber during rye sourdough bread production. Journal of Cereal Science, 57 (1), 30−38. DOI: 10.1016/j.jcs.2012.09.007.
1.1.
2012
Orumets, Kerti; Kevvai, Kaspar; Nisamedtinov, I; Tamm, T; Paalme, T. (2012). YAP1 over‐expression in Saccharomyces cerevisiae enhances glutathione accumulation at its biosynthesis and substrate availability levels. Biotechnology Journal, 7 (4), 566−568. DOI: 10.1002/biot.201100363.
5.2.
2012
Hälvin, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2012). Limitations of LC-MS in B-complex vitamins determination. 2nd International Vitamin Conference: 2nd International Vitamin Conference, Copenhagen (Denmark) 23-25 May 2012. Copenhagen: DTU Food National Food Institute.
5.2.
2012
Hälvin, Kristel; Mihhalevski, Anna; Nisamedtinov, Ildar; Ošeka, Aleksandra; Paalme, Toomas (2012). Determination of B-complex vitamins’ stability during rye sourdough breads production using LC-MS and stable isotope dilution assay. Clinical Chemistry and Laboratory Medicine, 50: Advances and Controversies in B-Vitamins and Choline, Leipzig (Germany) 5-8 March 2012. Ed. Mario Plebani. Germany: Walter de Gruyter & Co, A57−A57.
1.1.
2011
Kaseleht, K., Paalme, T., Nisamedtinov, I. (2011). Quantitative Analysis of Acetaldehyde in Foods Consumed by Children using SPME/GC-MS(Tof), On-fiber Derivatization and Deuterated Acetaldehyde as an Internal Standard. Agronomy Research, 9 (2), 395−401.
1.1.
2011
Nisamedtinov, I.; Kevvai, K.; Orumets, K.; Arike, L.; Sarand, I.; Korhola, M.; Paalme, T. (2011). Metabolic changes underlying the higher accumulation of glutathione in Saccharomyces cerevisiae mutants. Applied Microbiology and Biotechnology, 89 (4), 1029−1037. DOI: 10.1007/s00253-010-2946-z.
1.1.
2010
Nisamedtinov, I.; Kevvai, K.; Orumets, K.; Rautio, J.; Paalme, T. (2010). Glutathione accumulation in ethanol-stat fed-batch culture of Saccharomyces cerevisiae with a switch to cysteine feeding. Applied Microbiology and Biotechnology, 87 (1), 175−183. DOI: 10.1007/s00253-010-2502-x.
1.3.
2010
Nisamedtinov, Ildar; Orumets, Kerti; Kevvai, Kaspar; Viiard, Ene; Sarand, Inga; Paalme, Toomas (2010). Multilevel Control of GSH Accumulation in Mutant and Wild-Type Strains of S. cerevisiae Under Conditions of Smooth Cysteine Addition. Chemical Engineering Transactions: IBIC 2010 2nd International Conference on Industrial Biotechnology. Ed. Enrico Bardone, Aurelio Viglia., 91−96. DOI: 10.3303/CET1020016.
3.5.
2010
Hälvin, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2010). Simultaneous quantification of the B-complex vitamins in dried yeast using UPLC-MS and isotope labeled internal standards. Food and Nutrition: FoodBalt 2010 Tallinn 29. - 30. October 2010. Tallinn: Tallinn University of Technology, 93−93. (XVII).
5.2.
2010
Hälvin, Kristel; Ošeka, Aleksandra; Tammel, Kristel; Paalme, Toomas; Nisamedtinov, Ildar (2010). Effect of hydrolytic enzymes on simultaneous analysis of the B-complex vitamin content in dry yeast using LC-MS and isotope labeled internal standards. 1st International Vitamin Conference: 1st International Vitamin Conference, Copenhagen 19-21 Mai 2010. DTU Food National Food Institute.
2.3.
2009
Nisamedtinov, I. (2009). 13C and fluorescence labeling in yeast metabolic studies: Visualizing the time-spatial structure of metabolic network and determination of stress status in the cells. (Tallinna Tehnikaülikool). LAP LAMBERT Academic Publishing.
1.1.
2008
Nisamedtinov, I.; Lindsey, G. G.; Karreman, R.; Orumets, K.; Koplimaa, M.; Kevvai, K.; Paalme, T. (2008). The response of the yeast Saccharomyces cerevisiae to sudden vs. gradual changes in environmental stress monitored by expression of the stress response protein Hsp12p. FEMS Yeast Research, 8 (6), 829−838. DOI: 10.1111/j.1567-1364.2008.00391.x.
1.1.
2007
Kasemets K., Nisamedtinov I., Laht T.-M.,Abner K., Paalme T. (2007). Growth characteristics of Saccharomyces cerevisiae S288C in changing environmental conditions: auxo-accelerostat study. Antonie van Leeuwenhoek, 92 (1), 109−128. DOI: 10.1007/s10482-007-9141-y.
5.2.
2007
Nisamedtinov, I.; Lindsey, R.; Karreman, R.; Orumets, K.; Koplimaa, M.; Kevvai, K.; Paalme, T. (2007). The study of static and dynamic environmental stress of Saccharomyces cerevisiae using heat shock protein Hsp12p-Gfp2p construct. Physiology of Yeasts and Filamentous Fungi PYFF3: 3rd European Federation of Biotechnology Conference, Helsinki (Finland), June 13–16, 2007. Ed. Kuokka-Ihalainen, A.; Saloheimo, M.; Pakula, T. Helsingi: VTT Technical Research Centre of Finland, 70. (VTT Symposium ; 245).
5.2.
2007
Orumets, K.; Nisamedtinov, I.; Koplimaa, M.; Paalme, T. (2007). Effect of different stressful conditions on the expression of HSP12P-GFP2 fusion protein in Saccharomyces cerevisiae. FoodBalt-2007: 2nd Baltic Conference on Food Science and Technology, Kaunas, June 13-14 2007. Technologija, 27.
1.1.
2006
Paalme, Toomas; Nisamedtinov, Ildar; Abner, Kristo; Laht, Tiiu-Maie; Drews, Monika; Pehk, Tõnis (2006). Application of  <SUP>13</SUP>C-[2]- and <SUP>13</SUP>C[1,2] acetate in metabolic labelling studies of yeast and insect cells. Antonie van Leeuwenhoek, 89, 443−457. DOI: 10.1007/s10482-005-9053-7.
2.3.
2006
Nisamedtinov, I. (2006). 13C- ja fluoressentsmärgise kasutamine Saccharomyces spp. ainevahetuse uurimisel [Application of 13C and Fluorescence Labeling in Metabolic Studies of Saccharomyces spp.]. (Doktoritöö, Tallinna Tehnikaülikool). Tallinn: Tallinn University of Technology Press.
3.1.
2006
Kasemets, K.; Nisamedtinov, I.; Abner, K.; Paalme, T. (2006). The study of the fermentative growth of Saccharomyces cerevisiae S288C using auxo-accelerostat technique. In: Mendez-Vilas, A. (Ed.). Modern Multidisciplinary Applied Microbiology. Exploiting Microbes and Their Interactions (756−760). . Wiley-VCH.
3.1.
2006
Kasemets, K. Nisamedtinov, I., Abner, K. And Paalme, T. (2006). Study of the fermentative growth of S. Cerevisiae S288C using auxo-accelerostat technique. In: Mendez-Vilas, A (Ed.). Modern Multidisciplinary Applied Microbiology. Exploiting Microbes and Their Interaction. (756−762). . Wiley-VCH.
3.4.
2006
Nisamedtinov, I.; Lindsley, G.; Karreman, R.; Orumets, K.; Koplimaa, M.; Paalme, T. (2006). Effect of slowly increasing temperature and NaCl concentration on the expression of Hsp12-GFP2 fusion protein in Saccharomyces cerevisisae: an auxo-accelerostat study. In: Solvary, S; Toldi, O. (Ed.). FinMed 2006, 2nd International Conference on Bioreactor Technology in Cell, Tissue Culture and Biomedical Applications (102−112). . BioBien Innovations (BBi).
1.1.
2003
Kasemets, K.; Drews, M.; Nisamedtinov, I.; Adamberg, K.; Paalme, T (2003). Modification of A-stat for the characterization of microorganisms. Journal of Microbiological Methods, 55 (1), 187−200.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quasi-steady-state cultures. International Congress on Bioreactor Technology in Cell-, Tissue Culture and Biomedical Applications, 1st, Tampere, Finland 14 - 18 July 2003. Ed. Sorvari, S. BioBien Innovations (BBi), 218−225.
1.3.
1998
Drews, M.; Kasemets, K.; Nisamedtinov, I.; Paalme, T. (1998). Continuous cultivation of insect and yeast cells at maximum specific growth rate. Proceedings of the Estonian Academy of Sciences. Chemistry, 47, 175−188.

Industrial property

30.09.2020

Otsi projekti

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ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF9189B-kompleks vitamiinide metaboloomi analüüs toidu tootmise ahelas.01.01.201231.12.2015Toomas PaalmeTallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond57 600,00 EUR
MUUEU23942Bioglütserooli kasutamine pärmiproduktide toorainena01.05.200631.08.2006Toomas PaalmeAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus6 395,38 EUR
ETFETF7652Funktsionaalsete kasvufaktorite mõju ravimvalkude tootlikkusele imetajarakkudes 01.01.200831.12.2011Monika DrewsVähiuuringute Tehnoloogia Arenduskeskus AS37 196,11 EUR
ETFETF7323Keskkonnatingimuste mõju glutatiooni akumulatsioonile ja ainevahetusele Saccharomyces cerevisiae rakkudes01.01.200831.12.2011Ildar NisamedtinovTallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond71 043,20 EUR
SFSF0142497s03Postgenoomne protsessidisain toidu- ja keskkonnabiotehnoloogias01.01.200331.12.2007Raivo ViluTallinna Tehnikaülikool, Matemaatika-loodusteaduskond348 925,64 EUR
MUUEU27591Rakkude kasvu stimuleerivad bioaktiivsed peptiidid pärmi ekstraktist - eeluuring01.11.200729.02.2008Toomas Paalme; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus9 410,93 EUR
MUUEU29994Support for Competence Center of Food and Fermentation Technologies01.01.200930.06.2015Raivo Vilu; Toomas Paalme; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus7 028 458,00 EUR
IUTIUT19-27Süsteemibioloogia rakendused toituteaduses ja -tehnoloogias01.01.201431.12.2019Toomas PaalmeTallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond; Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut852 000,00 EUR
RESTARESTA13Tahkefaasi fermentatsiooni protsessid toidu tootmise kaassaaduste väärindamisel01.01.202131.01.2023Toomas PaalmeTallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut381 750,00 EUR
SFSF0140090s08Toidu süsteemibioloogia ja füüsika01.01.200831.12.2013Toomas PaalmeTallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond705 093,40 EUR
MUUEU22704Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus27.10.200531.10.2007Raivo Vilu; Toomas Paalme; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus1 725 043,14 EUR
MUUEU19691Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus27.10.200426.10.2005Raivo Vilu; Toomas Paalme; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus338 077,35 EUR
MUUEU27607Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus01.11.200730.06.2008Raivo Vilu; Toomas Paalme; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus657 826,17 EUR
MUUEU28668Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus01.07.200830.06.2009Toomas Paalme; Raivo Vilu; Urmas SannikAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus903 909,35 EUR
MUUEU48667Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus01.07.201530.06.2022Martin LallAS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus5 697 954,91 EUR