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Margus Varjak

https://etis.ee/CV/Margus_Varjak/eng
6.08.1983
margus.varjak@gmail.com

Career

Institutions and positions
01.01.2021–31.12.2023   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Associate Professor of Virology (1,00)
01.10.2020–31.12.2020   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Research Fellow in Virology (1,00)
01.09.2018–15.09.2020   
University of Glasgow, Research Associate (Within Prof Massimo Palmarini research group) (1,00)
01.09.2017–01.09.2018   
University of Glasgow, Research Associate (Within Prof Alain Kohl research group) (1,00)
01.09.2015–31.08.2017   
University of Glasgow, Marie Skłodowska-Curie Individual Fellowship (1,00)
01.03.2014–31.08.2015   
University of Glasgow, Research Assistant (Within Prof Esther Schnettler research group) (1,00)
01.09.2012–28.02.2014   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Specialist (1,00)
01.01.2011–31.08.2012   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Specialist (0,34)
 
 
Education
2008–06.12.2013   
University of Tartu, Faculty of Science and Technology, Institute of Technology, PhD-student
2006–2008   
University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology, Master's degree (cum laude)
2002–2005   
University of Tartu, Faculty of Biology and Geograpgy, Bachelor's degree (cum laude)
1991–2002   
Pärnu Ülejõe Gymnasium

Qualifications

Academic degrees
Margus Varjak, Doctor's Degree, 2013, (sup) Andres Merits, Functional analysis of viral and host components of alphavirus replicase complexes, University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu.
Margus Varjak, Master's Degree, 2008, (sup) Andres Merits, Semliki Forest viiruse mittestruktuurse valgu nsP3 degradatsioonisignaali uurimine (The Study of Degradation Signal of Semliki Forest Virus Non-Structural Protein nsP3), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering
 
 

Projects in progress

Completed projects

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2020
Bryden, Steven R.; Pingen, Marieke; Lefteri, Daniella A.; Miltenburg, Janne; Delang, Leen; Jacobs, Sofie; Abdelnabi, Rana; Neyts, Johan; Pondeville, Emilie; Major, Jack; Mueller, Marietta; Khalid, Henna; Tuplin, Andrew; Varjak, Margus; Merits, Andres; Edgar, Julia; Graham, Gerard J.; Shams, Kave; McKimmie, Clive S. (2020). Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site. Science Translational Medicine, 12 (527), ARTN eaax2421. DOI: 10.1126/scitranslmed.aax2421.
1.1.
2020
Royle, Jamie; Ramírez-Santana, Carolina; Akpunarlieva, Snezhana; Donald, Claire L.; Gestuveo, Rommel J.; Anaya, Juan-Manuel; Merits, Andres; Burchmore, Richard; Kohl, Alain; Varjak, Margus (2020). Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection. Viruses, 12 (5), 524. DOI: 10.3390/v12050524.
1.1.
2020
McFarlane, Melanie; Almire, Floriane; Kean, Joy; Donald, Claire L.; McDonald, Alma; Wee, Bryan; Lauréti, Mathilde; Varjak, Margus; Terry, Sandra; Vazeille, Marie; Gestuveo, Rommel J.; Dietrich, Isabelle; Loney, Colin; Failloux, Anna-Bella; Schnettler, Esther; Pondeville, Emilie; Kohl, Alain; Fernandez-Sesma, Ana (2020). The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression. mSphere, 5 (2). DOI: 10.1128/mSphere.00081-20.
1.1.
2018
Mutso, Margit; Morro, Ainhoa Moliner; Smedberg, Cecilia; Kasvandik, Sergo; Aquilimeba, Muriel; Teppor, Mona; Tarve, Liisi; Lulla, Aleksei; Lulla, Valeria; Saul, Sirle; Thaa, Bastian; McInerney, Gerald M.; Merits, Andres; Varjak, Margus (2018). Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus. Viruses, 10 (5), ARTN 226. DOI: 10.3390/v10050226.
1.1.
2018
Varjak, Margus; Dietrich, Isabelle; Sreenu, Vattipally B.; Till, Bethan Eluned; Merits, Andres; Kohl, Alain; Schnettler, Esther (2018). Spindle-E Acts Antivirally Against Alphaviruses in Mosquito Cells. Viruses, 10 (2), ARTN 88.10.3390/v10020088.
1.1.
2018
Lourenco-de-Oliveira, Ricardo; Marques, Joao T.; Sreenu, Vattipally B.; Nten, Celestine Atyame; Guimaraes Rocha Aguiar, Eric Roberto; Varjak, Margus; Kohl, Alain; Failloux, Anna-Bella (2018). Culex quinquefasciatus mosquitoes do not support replication of Zika virus. Journal of General Virology, 99 (2), 258−264. DOI: 10.1099/jgv.0.000949.
1.1.
2018
Varjak, Margus; Leggewie, Mayke; Schnettler, Esther (2018). The antiviral piRNA response in mosquitoes? Journal of General Virology, 99 (12), 1551−1562. DOI: 10.1099/jgv.0.001157.
1.1.
2018
Donald, Claire L.; Varjak, Margus; Guimaraes Rocha Aguiar, Eric Roberto; Marques, Joao T.; Sreenu, Vattipally B.; Schnettler, Esther; Kohl, Alain (2018). Antiviral RNA Interference Activity in Cells of the Predatory Mosquito, Toxorhynchites amboinensis. Viruses, 10 (12), ARTN 694.10.3390/v10120694.
1.1.
2017
Varjak, M.; Donald, C.L.; Mottram, T.; Sreenu, V.B.; Merits, A.; Maringer, K.; Schnettler, E.; Kohl, A. (2017). Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Neglected Tropical Diseases, 11 (10).10.1371/journal.pntd.0006010.
1.1.
2017
Royle, J.; Donald, C.L.; Merits, A.; Kohl, A.; Varjak, M. (2017). Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses. The Veterinary Journal, 230, 62−64.10.1016/j.tvjl.2017.10.009.
1.1.
2017
Varjak, Margus; Maringer, Kevin; Watson, Mick; Sreenu, Vattipally B.; Fredericks, Anthony C.; Pondeville, Emilie; Donald, Claire L.; Sterk, Jelle; Kean, Joy; Vazeille, Marie; Failloux, Anna-Bella; Kohl, Alain; Schnettler, Esther (2017). Aedes aegypti Piwi4 Is a Noncanonical PIWI Protein Involved in Antiviral Responses. mSphere, 2 (3), ARTN e00144-17.10.1128/mSphere.00144-17.
1.1.
2017
Mottram, Timothy J.; Li, Ping; Dietrich, Isabelle; Shi, Xiaohong; Brennan, Benjamin; Varjak, Margus; Kohl, Alain (2017). Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids. PLoS Neglected Tropical Diseases, 11 (12), ARTN e0006155.10.1371/journal.pntd.0006155.
1.1.
2016
Rainey, S.M.; Martinez, J.; Juneja, P.; Sarkies, P.; Lulla, A.; McFarlane, M.; Schnettler, E.; Varjak, M.; Merits, A.; Jiggins, F.M.; Kohl, A. (2016). Wolbachia blocks viral genome replication early in infection without a transcriptional response by the endosymbiont or host small RNA pathways. PLoS Pathogens, 12, e1005536. DOI: 10.1371/journal.ppat.1005536.
1.1.
2016
Karlas, A.; Berre, S.; Couderc, T.; Varjak, M., Braun, P.; Meyer, M., Gangneux, N; Karo-Astover, L.; Weege, F.; Raftery, M.; Schönrich, G.; Klemm, U.; Wurzlbauer, A.; Bracher, F.; Merits, A.; Meyer, T.F.; Lecuit, M. (2016). A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nature Communications, 7, 11320. DOI: 10.1038/ncomms11320.
1.1.
2016
Donald, Claire L.; Brennan, Benjamin; Cumberworth, Stephanie L.; Rezelj, Veronica V.; Clark, Jordan J.; Cordeiro, Marli T.; de Oliveira Franca, Rafael Freitas; Pena, Lindomar J.; Wilkie, Gavin S.; Filipe, Ana Da Silva; Davis, Christopher; Hughes, Joseph; Varjak, Margus; Selinger, Martin; Zuvanov, Luiza; Owsianka, Ania M.; Patel, Arvind H.; McLauchlan, John; Lindenbach, Brett D.; Fall, Gamou ... Kohl, Alain (2016). Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil. PLoS Neglected Tropical Diseases, 10 (10), ARTN e0005048.10.1371/journal.pntd.0005048.
1.1.
2015
Utt, A.; Das, P.K.; Varjak, M.; Lulla, V.; Lulla, A.; Merits, A. (2015). Mutations conferring a non-cytotoxic phenotype on Chikungunya virus replicons compromise enzymatic properties of non-structural protein 2. Journal of Virology, 89 (6), 3145−3162.10.1128/JVI.03213-14.
1.1.
2013
Varjak, M.; Saul, S.; Arike, L.; Lulla, A.; Peil, L.; Merits, A. (2013). Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus. Journal of Virology, 87 (18), 10293−10312.10.1128/JVI.01105-13.
1.1.
2012
Panas, M.D.; Varjak, M.; Lulla, A.; Eng, K.E.; Merits, A.; Karlsson-Hedestam, G.B.; McInerney, G.M. (2012). Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection. Molecular Biology of the Cell, 23 (24), 4701−4712.10.1091/mbc.E12-08-0619.
1.1.
2012
Rodriguez-Andres, J.; Rani, S.; Varjak, M.; Chase-Topping, M.E.; Beck, M.H.; Ferguson, M.C.; Schnettler, E.; Fragkoudis, R.; Barry, G.; Merits, A.; Fazakerley, J.K.; Strand, M.R.; Kohl, A. (2012). Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus. PLoS Pathogens, 8 (11), e1002977.10.1371/journal.ppat.1002977.
1.1.
2011
Pohjala, L.; Utt, A.; Varjak, M.; Merits, A.; Lulla, A.; Ahola, T.; Tammela, P. (2011). Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays. PLoS ONE, 6 (12), e28923.10.1371/journal.pone.0028923.
1.1.
2010
Varjak, M., Žusinaite, E.; Merits, A. (2010). Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. Journal of Virology, 84, 2352−2364.10.1128/JVI.01540-09.

Industrial property

25.09.2020

Margus Varjak

https://etis.ee/CV/Margus_Varjak/est
6.08.1983
margus.varjak@gmail.com

Teenistuskäik

Töökohad ja ametid
01.01.2021–31.12.2023   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, viroloogia kaasprofessor (1,00)
01.10.2020–31.12.2020   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, viroloogia vanemteadur (1,00)
01.09.2018–15.09.2020   
Glasgow Ülikool, Teadur, Prof Massimo Palmarini uurimisgrupis (1,00)
01.09.2017–01.09.2018   
Glasgow Ülikool, Teadur, Prof Alain Kohli uurimisgrupis (1,00)
01.09.2015–31.08.2017   
Glasgow Ülikool, Marie Skłodowska-Curie Individuaalne Uurimistoetus (1,00)
01.03.2014–31.08.2015   
Glasgow Ülikool, Nooremteadur, Prof Esther Schnettleri uurimisgrupis (1,00)
01.09.2012–28.02.2014   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, spetsialist (1,00)
01.01.2011–31.08.2012   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, spetsialist (0,34)
 
 
Haridustee
2008–06.12.2013   
Tartu Ülikool, Tehnika ja tehnoloogia doktorant
2006–2008   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, loodusteaduse magister (biotehnoloogia ja biomeditsiin)
2002–2005   
Tartu Ülikool, loodusteaduse bakalaureus (geenitehnoloogia)
1991–2002   
Pärnu Ülejõe Gümnaasium

Kvalifikatsioon

Teaduskraadid
Margus Varjak, Doctor's Degree, 2013, (sup) Andres Merits, Functional analysis of viral and host components of alphavirus replicase complexes, University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu.
Margus Varjak, Master's Degree, 2008, (sup) Andres Merits, Semliki Forest viiruse mittestruktuurse valgu nsP3 degradatsioonisignaali uurimine (The Study of Degradation Signal of Semliki Forest Virus Non-Structural Protein nsP3), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); TÄPSUSTUS: Alphaviiruste perekonda kuuluva Semliki Forest viiruse replikatsioonikompleksi kujunemise ja selle funktsionaalse reguleerimise uurimine

Jooksvad projektid

Lõppenud projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2020
Bryden, Steven R.; Pingen, Marieke; Lefteri, Daniella A.; Miltenburg, Janne; Delang, Leen; Jacobs, Sofie; Abdelnabi, Rana; Neyts, Johan; Pondeville, Emilie; Major, Jack; Mueller, Marietta; Khalid, Henna; Tuplin, Andrew; Varjak, Margus; Merits, Andres; Edgar, Julia; Graham, Gerard J.; Shams, Kave; McKimmie, Clive S. (2020). Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site. Science Translational Medicine, 12 (527), ARTN eaax2421. DOI: 10.1126/scitranslmed.aax2421.
1.1.
2020
Royle, Jamie; Ramírez-Santana, Carolina; Akpunarlieva, Snezhana; Donald, Claire L.; Gestuveo, Rommel J.; Anaya, Juan-Manuel; Merits, Andres; Burchmore, Richard; Kohl, Alain; Varjak, Margus (2020). Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection. Viruses, 12 (5), 524. DOI: 10.3390/v12050524.
1.1.
2020
McFarlane, Melanie; Almire, Floriane; Kean, Joy; Donald, Claire L.; McDonald, Alma; Wee, Bryan; Lauréti, Mathilde; Varjak, Margus; Terry, Sandra; Vazeille, Marie; Gestuveo, Rommel J.; Dietrich, Isabelle; Loney, Colin; Failloux, Anna-Bella; Schnettler, Esther; Pondeville, Emilie; Kohl, Alain; Fernandez-Sesma, Ana (2020). The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression. mSphere, 5 (2). DOI: 10.1128/mSphere.00081-20.
1.1.
2018
Mutso, Margit; Morro, Ainhoa Moliner; Smedberg, Cecilia; Kasvandik, Sergo; Aquilimeba, Muriel; Teppor, Mona; Tarve, Liisi; Lulla, Aleksei; Lulla, Valeria; Saul, Sirle; Thaa, Bastian; McInerney, Gerald M.; Merits, Andres; Varjak, Margus (2018). Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus. Viruses, 10 (5), ARTN 226. DOI: 10.3390/v10050226.
1.1.
2018
Varjak, Margus; Dietrich, Isabelle; Sreenu, Vattipally B.; Till, Bethan Eluned; Merits, Andres; Kohl, Alain; Schnettler, Esther (2018). Spindle-E Acts Antivirally Against Alphaviruses in Mosquito Cells. Viruses, 10 (2), ARTN 88.10.3390/v10020088.
1.1.
2018
Lourenco-de-Oliveira, Ricardo; Marques, Joao T.; Sreenu, Vattipally B.; Nten, Celestine Atyame; Guimaraes Rocha Aguiar, Eric Roberto; Varjak, Margus; Kohl, Alain; Failloux, Anna-Bella (2018). Culex quinquefasciatus mosquitoes do not support replication of Zika virus. Journal of General Virology, 99 (2), 258−264. DOI: 10.1099/jgv.0.000949.
1.1.
2018
Varjak, Margus; Leggewie, Mayke; Schnettler, Esther (2018). The antiviral piRNA response in mosquitoes? Journal of General Virology, 99 (12), 1551−1562. DOI: 10.1099/jgv.0.001157.
1.1.
2018
Donald, Claire L.; Varjak, Margus; Guimaraes Rocha Aguiar, Eric Roberto; Marques, Joao T.; Sreenu, Vattipally B.; Schnettler, Esther; Kohl, Alain (2018). Antiviral RNA Interference Activity in Cells of the Predatory Mosquito, Toxorhynchites amboinensis. Viruses, 10 (12), ARTN 694.10.3390/v10120694.
1.1.
2017
Varjak, M.; Donald, C.L.; Mottram, T.; Sreenu, V.B.; Merits, A.; Maringer, K.; Schnettler, E.; Kohl, A. (2017). Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Neglected Tropical Diseases, 11 (10).10.1371/journal.pntd.0006010.
1.1.
2017
Royle, J.; Donald, C.L.; Merits, A.; Kohl, A.; Varjak, M. (2017). Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses. The Veterinary Journal, 230, 62−64.10.1016/j.tvjl.2017.10.009.
1.1.
2017
Varjak, Margus; Maringer, Kevin; Watson, Mick; Sreenu, Vattipally B.; Fredericks, Anthony C.; Pondeville, Emilie; Donald, Claire L.; Sterk, Jelle; Kean, Joy; Vazeille, Marie; Failloux, Anna-Bella; Kohl, Alain; Schnettler, Esther (2017). Aedes aegypti Piwi4 Is a Noncanonical PIWI Protein Involved in Antiviral Responses. mSphere, 2 (3), ARTN e00144-17.10.1128/mSphere.00144-17.
1.1.
2017
Mottram, Timothy J.; Li, Ping; Dietrich, Isabelle; Shi, Xiaohong; Brennan, Benjamin; Varjak, Margus; Kohl, Alain (2017). Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids. PLoS Neglected Tropical Diseases, 11 (12), ARTN e0006155.10.1371/journal.pntd.0006155.
1.1.
2016
Rainey, S.M.; Martinez, J.; Juneja, P.; Sarkies, P.; Lulla, A.; McFarlane, M.; Schnettler, E.; Varjak, M.; Merits, A.; Jiggins, F.M.; Kohl, A. (2016). Wolbachia blocks viral genome replication early in infection without a transcriptional response by the endosymbiont or host small RNA pathways. PLoS Pathogens, 12, e1005536. DOI: 10.1371/journal.ppat.1005536.
1.1.
2016
Karlas, A.; Berre, S.; Couderc, T.; Varjak, M., Braun, P.; Meyer, M., Gangneux, N; Karo-Astover, L.; Weege, F.; Raftery, M.; Schönrich, G.; Klemm, U.; Wurzlbauer, A.; Bracher, F.; Merits, A.; Meyer, T.F.; Lecuit, M. (2016). A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nature Communications, 7, 11320. DOI: 10.1038/ncomms11320.
1.1.
2016
Donald, Claire L.; Brennan, Benjamin; Cumberworth, Stephanie L.; Rezelj, Veronica V.; Clark, Jordan J.; Cordeiro, Marli T.; de Oliveira Franca, Rafael Freitas; Pena, Lindomar J.; Wilkie, Gavin S.; Filipe, Ana Da Silva; Davis, Christopher; Hughes, Joseph; Varjak, Margus; Selinger, Martin; Zuvanov, Luiza; Owsianka, Ania M.; Patel, Arvind H.; McLauchlan, John; Lindenbach, Brett D.; Fall, Gamou ... Kohl, Alain (2016). Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil. PLoS Neglected Tropical Diseases, 10 (10), ARTN e0005048.10.1371/journal.pntd.0005048.
1.1.
2015
Utt, A.; Das, P.K.; Varjak, M.; Lulla, V.; Lulla, A.; Merits, A. (2015). Mutations conferring a non-cytotoxic phenotype on Chikungunya virus replicons compromise enzymatic properties of non-structural protein 2. Journal of Virology, 89 (6), 3145−3162.10.1128/JVI.03213-14.
1.1.
2013
Varjak, M.; Saul, S.; Arike, L.; Lulla, A.; Peil, L.; Merits, A. (2013). Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus. Journal of Virology, 87 (18), 10293−10312.10.1128/JVI.01105-13.
1.1.
2012
Panas, M.D.; Varjak, M.; Lulla, A.; Eng, K.E.; Merits, A.; Karlsson-Hedestam, G.B.; McInerney, G.M. (2012). Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection. Molecular Biology of the Cell, 23 (24), 4701−4712.10.1091/mbc.E12-08-0619.
1.1.
2012
Rodriguez-Andres, J.; Rani, S.; Varjak, M.; Chase-Topping, M.E.; Beck, M.H.; Ferguson, M.C.; Schnettler, E.; Fragkoudis, R.; Barry, G.; Merits, A.; Fazakerley, J.K.; Strand, M.R.; Kohl, A. (2012). Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus. PLoS Pathogens, 8 (11), e1002977.10.1371/journal.ppat.1002977.
1.1.
2011
Pohjala, L.; Utt, A.; Varjak, M.; Merits, A.; Lulla, A.; Ahola, T.; Tammela, P. (2011). Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays. PLoS ONE, 6 (12), e28923.10.1371/journal.pone.0028923.
1.1.
2010
Varjak, M., Žusinaite, E.; Merits, A. (2010). Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. Journal of Virology, 84, 2352−2364.10.1128/JVI.01540-09.

Tööstusomand

25.09.2020

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ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
ETFETF7407Alphavirus replication, inhibition and virus-host interactions.01.01.200831.12.2011Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old)66 495,46 EUR
ETFETF9400Exploration of space of alphavirus-encoded short linear interaction motifs mediating hijacking of host pathways and facilities.01.01.201231.12.2014Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu29 736,00 EUR
SFSF0180087s08Analysis of the replication, viral-host interactions and virus induce pathogenesis of viruses with RNA genomes and inhibition or practical usage of these processes.01.01.200831.12.2013Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu653 945,96 EUR
ETFETF6609Mechanisms involved in the Semliki Forest virus replication and virus-host interactions: basic studies and potential use for gene technology.01.01.200631.12.2007Andres MeritsUniversity of Tartu, Faculty of Biology and Geography23 291,96 EUR
MOBTPMOBTP195Viral genomes- more than RNA sequence01.10.202030.09.2022Margus VarjakUniversity of Tartu, Faculty of Science and Technology, Institute of Technology108 003,54 EUR
COVSGCOVSG7Antiviral Carbohydrates: Applications in Disinfectants, Cosmetics and Pharmaceutical Formulations01.10.202031.12.2021Rando TuvikeneTallinn University, School of Natural Sciences and Health200 000,00 EUR