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Olen nõus

Monika Drews

https://etis.ee/CV/Monika_Drews/est
29.06.1967
5596 1592
monika.drews@ttk.ee
MDrewsinee@gmail.com

Teenistuskäik

Töökohad ja ametid
2017–...   
Tallinna Tervishoiu Kõrgkool, Meditsiinitehnilise hariduse keskus, Farmatseudi õppekava, õppejõud-õpetaja (1,00)
2016–2017   
Tallinna Tervishoiu Kõrgkool, Farmaatsia õppetool, õppejõud (1,00)
2015–2016   
Tallinna Tervishoiu Kõrgkool, Meditsiinitehnilise hariduse keskus, Farmatseudi õppekava, õppejõud (0,50)
2009–2014   
Vähiuuringute Tehnoloogia Arenduskeskus AS, Projekti koordinaator (1.00), rakuline immunoteraapia (1,00)
2008–2013   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Molekulaardiagnostika õppetool, Vanemteadur (0,25)
2007–2007   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Molekulaardiagnostika õppetool, Erakorraline vanemteadur (0,25)
2005–2007   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Molekulaardiagnostika õppetool, Erakorraline vanemteadur (0,25)
2005–2009   
Vähiuuringute Tehnoloogia Arenduskeskus AS, Projektijuht, Projekt: Rekombinantsete valkude bioprotsesside optimeerimine (1,00)
2002–2005   
Keemilise ja Bioloogilise Füüsika Instituut, Welcome Trust teadur, Molekulaargeneetika laboratoorium, vähiuuringute töörühm (1,00)
2000–2002   
Keemilise ja Bioloogilise Füüsika Instituut, vanemteadur, Molekulaargeneetika laboratoorium, vähiuuringute töörühm (1,00)
1996–2000   
Keemilise ja Bioloogilise Füüsika Instituut, teadur, Molekulaargeneetika laboratoorium, mikrobioloogia-biotehnoloogia töögrupp (1,00)
1991–1996   
Keemilise ja Bioloogilise Füüsika Instituut, nooremteadur, Molekulaargeneetika laboratoorium, mikrobioloogia-biotehnoloogia töögrupp (1,00)
1989–1990   
Keemilise ja Bioloogilise Füüsika Instituut, insener, Molekulaargeneetika laboratoorium, mikrobioloogia-biotehnoloogia töögrupp (0,50)
 
 
Haridustee
1997–1998   
Rootsi Kuninglik Tehnoloogia Instituut, Stockholm, Rootsi, külalisdoktorant, loomsete rakukultuuride tehnoloogia, prof. L.Häggström, Loomsete Rakukultuuride Tehnoloogia uurimisgrupp
1995–1999   
Tallinna Tehnikaülikool, biotehnoloogia, loodusteaduste doktor, Ph.D
1985–1990   
Tartu Ülikool, cum laude, bioloogia - biokeemia eriala, võrdsustatud teadusmagistriga, M. Sc
1974–1985   
Tallinna 44. Keskkool, keemia eriklass
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2018−2019   
TTK institutsionaalse akrediteerimise "Hindamise analüüs"i töörühm
2005−2014   
Rakulabori loomine ja juhtimine, Vähiuuringute Tehnoloogia Arenduskeskus, Tallinn
2005−2009   
Projektijuht, VTAK
 
 
Lisainfo
2020 - Täiendusõppe kursus "Raamatukogu infootsing (e-kursus)", Tallinna Tervishoiu Kõrgkool, Tallinn, Eesti (13.04.2020 - 11.05.2020), 26 akadeemilist tundi, tunnistus
2019 - Toitumis- ja liikumisravi konverents, SA Põhja-Eesti Regionaalhaigla, Tallinn, Eesti (17.01.2019) 8 tundi, 8 täienduskoolitupunkti, tunnistus
2018 - Ravimtaimed toitumisteraapias, Rahvatervise Akadeemia, Tallinn, Eesti (16.11.2018) 26 akad. tundi, tunnistus
2018 - Õpetamine kõrgkoolis - oskused, strateegiad ja võimalused, Tallinna Ülikool, Tallinn, Eesti (08.11.2017 - 31.01.2018), 92 akadeemilist tundi, tunnistus
2017 - Täienduskoolitus: Toitumine tervele ja haigele II, Koolitaja: Ida-Tallinna Keskhaigla, Tallinn,Eesti (30.10-31.10.2017) 16 täiendustundi (tõend Nr 142/26)
2017 - Täienduskoolitus: Toitumine tervele ja haigele, Koolitaja: Ida-Tallinna Keskhaigla, Tallinn, Eesti (19.01-20.01.2017) 16 täiendustundi (tõend Nr 5/8)
2016 - Täienduskoolitus; ILADS (International Lyme and Associated Diseases Society) 6th European Conference, Helsinki, Finland (CME accredited conference) (10 – 11. 06. 2016); Meditsiinilise jätkukoolituse punktid (CME points awarded by the Faculty of Medicine, University of Helsinki): Infektsioonilised haigused 2.0 tundi; kliiniline mikrobioloogia 2.0 tundi; pediaatria 1.0 tundi ja patoloogia 5.0 tundi), sertifikaat
2015 - Ettevõtluskoolitus, SOK Promstandart, Tallinn, Eesti (28.11.2014 - 30.01. 2015) 160 tundi, tunnistus
2014 - Ekspordikoolitus, Koolitaja: Tõnu Hein, HeiVäl Consulting, Mektory, Tallinn, Eesti (2-10.04.2014) 24 tundi, tunnistus
2012 - NCO Cell Therapy Cluster - GMP training, Regea Cell and Tissue Center BioMediTech, Tampere Ülikool, Soome (10-12.4.2012), tunnistus
2006 - How to Write a Competitive Proposal for FP7 kursus, Koolitaja: Dr. Sean McCarty, Hyperion Ltd., Tallinn, Eesti (28. 11.2006)
2004 - Projektijuhtide koolitus, ESKO koolitus, Tallinn, Eesti (20-21.1.2004)
2003 - Biomedical Magnetic Resonance kursus, Göteburgi Ülikool, Rootsi, jaanuar 2003
2001 - Laboratory Animal Science and Techniques kursus, Tallinna Tehnikaülikool, Tallinn, Eesti (23.11 - 14.12. 2001), sertifikaat
1997 - Physiology of Industrial Microorganisms kursus, Rootsi Kuninglik Tehnoloogia Instituut, Stockholm, Rootsi, 1997
1996 - Animal Cell Technology kursus, Rootsi Kuninglik Tehnoloogia Instituut, Stockholm, Rootsi (15-18.4.1996)
1994 - Inglise keele kursus (kõrgem kesktase), Soros International House, Tallinn, Eesti (5.09 – 23.11. 1994), kõrgema kesktaseme sertifikaat
1993 - Animal Cell Technology kursus, Rootsi Kuninglik Tehnoloogia Instituut, Stockholm, Rootsi (19-22.4.1993)

Kvalifikatsioon

Teaduskraadid
Monika Drews, doktorikraad, 1999, (juh) Raivo Vilu, Metabolism of Insect cells in Periodic and Continuous Cultures: Application of Chemostat and Turbidostat Cultivations in Production of Recombinant Proteins (Putukarakkude metabolism perioodilistes ja läbivoolukultuurides: kemostaat ja turbidostaat kultiveerimise rakendamine rekombinantsete valkude tootmisel), Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond.
 
 
Teaduspreemiad ja tunnustused
2019, Monika Drews, Üliõpilas- ja õpilasesinduse tunnustus suurepärase töö eest Tallinna Tervishoiu Kõrgkoolis
1993, Monika Drews, Georg Sorose stipendium, 1993
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); CERCS KLASSIFIKAATOR: T490 Biotehnoloogia ; TÄPSUSTUS: Kultiveeritavate imetaja-ja putukarakkude füsioloogia ja metabolism, vähiteraapias potentsiaali omavate rekombinantsete valkude ja monoklonaalsete antikehade ekspressiooni optimeerimine. Seerumvabade söötmete ja uudsete söötmelisandite väljatöötamine erinevatele rakukultuuridele. Inimese loomulike tappurrakkude kultiveerimise ja aktiveerimise uurimine.
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); TÄPSUSTUS: Biotehnoloogia, kultiveeritavate imetaja-ja putukarakkude füsioloogia ja metabolism, vähiteraapias potentsiaali omavate rekombinantsete valkude ja monoklonaalsete antikehade ekspressiooni optimeerimine
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika)
 
 
Lisainfo
Loodusteaduste doktor
Tallinna Tehnikaülikool, 1999

Jooksvad projektid

Lõppenud projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.3.
2020
Drews, Monika (2020). Haigustekitajad Eesti puukides. Väike hammustus võib viia suure probleemini. Apteek Täna, 2, 88−91.
3.2.
2019
Titma, T.; Ruuben, L.; Drews, M. (2019). Compounding, extemporaneous prepare or reconstitution of the radiopharmaceuticals. In: COE EDQM Proceedings of International Conferences, EDQM & European Pharmacopoeia: State-of-the-art Science for Tomorrow’s Medicines. Strasbourg: COE EDQM Publications.
3.5.
2019
Juurmaa, Margit; Vainoja, Ave; Drews, Monika; Parts, Laine (2019). Seleeni sisalduse määramise metoodika välja töötamine ja valideerimine. Tervisevaldkonna uuringute infopäev, Tallinn, Eesti, 1.10.2019. Toim. Angela Ivask. Tervisevaldkonna uuringute infopäev: elektroonselt avaldatud, 9.
6.6.
2019
Drews, Monika (2019). Farmatseutide pere täienes 28 erialaspetsialistiga. Eesti Rohuteadlane, 3, 11.
1.2.
2014
Värv, Kairi; Rumvolt, Reet; Järvekülg, Lilian; Drews, Monika; Ehin, Riin (2014). Potential of In Vitro Expanded NK Cells as a Highly Cytotoxic Tool for Fighting Melanoma. Journal for Clinical Studies, 6 (4), 46−51.
1.2.
2014
Voodla, Karoli; Rumvolt, Reet; Aints, Alar; Drews, Monika (2014). Medical Colloids In Design of Mammalian Serum-Free Media. International Journal of Emerging Trends in Pharmaceutical Sciences, 2 (1), 1−4.
5.2.
2012
Värv, Kairi; Rumvolt, Reet; Drews, Monika (2012). Characterization of human natural killer cell culture by flow cytometry. FACS Users Meeting „Advances in flow cytometry“ November 6-7, Tallinn, 2012. http://inbio.ee/2012/11/16/eesti-facsi-kasutajate-konverents-advances-in-flo,.
3.1.
2010
Drews, Monika; Hunt, Reet (2010). Growth and Production Characteristics of Four Mammalian Cell Lines on a Cost-Effective Serum-Free Medium. In: Cells and Culture (223−227). Springer. DOI: 10.1007/978-90-481-3419-9_38.
3.1.
2010
Voodla, K., Rumvolt, R., Drews, M. (2010). Extract of Selenium-enriched Yeast Enhances Growth and Production Parameters of Mammalian Cell Lines in Serum-free Suspension Cultures. Journal of Biotechnology, 150. , 400. (1). DOI: 10.1016/j.jbiotec.2010.09.522.
5.1.
2010
Voodla, Karoli; Rumvolt, Reet; Drews, Monika (2010). Extract of Selenium-enriched Yeast Enhances Growth and Production Parameters of Mammalian Cell Lines in Serum-free Suspension Cultures. 14th International Biotechnology Symposium and Exhibition. Biotechnology for the Sustainability of Human Society. 14-18 September, Palacongressi, Rimini, Italy 2010, P 1533.. P 1533.
5.1.
2009
Voodla, Karoli; Hunt, Reet; and Drews, Monika (2009). The effect of extract of selenium-enriched yeast on growth of hybridoma and CHO cells. 21th Meeting of the European Society for Animal Cell Technology (ESACT) „Cellular Solutions for Clinical Challenges“, June 7-10, 2009, Dublin, Ireland. Dublin, Ireland, 387.
6.7.
2009
Drews, M., Rumvolt, R., Voodla, K. (2009). PCT WO 2009/149719 A1 The use of extract of selenium enriched yeast (Se-YE) in mammalian cell culture media formulations. In: .. World Intellectual Property Organization.
1.1.
2007
Hunt, R.; Bragina, O.; Drews, M.; Kasak, L.; Timmusk, S.; Valkna, A.; Kogerman, P.; Järvekülg, L. (2007). Generation and Characterization of mouse monoclonal antibody 5E1 against human transcription factor Gli3. Hybridoma, 26 (3), 131−138.
5.1.
2007
Drews, Monika; Hunt, Reet (2007). Growth and production characteristics of four mammalian cell lines on a cost-effective serum-free medium. In: Cells & Culture (3.32).20th Meeting of the European Society for Animal Cell technology (ESACT), June 17-20, 2007, Dresden, Germany.
1.1.
2006
Paalme, Toomas; Nisamedtinov, Ildar; Abner, Kristo; Laht, Tiiu-Maie; Drews, Monika; Pehk, Tõnis (2006). Application of  <SUP>13</SUP>C-[2]- and <SUP>13</SUP>C[1,2] acetate in metabolic labelling studies of yeast and insect cells. Antonie van Leeuwenhoek, 89, 443−457. DOI: 10.1007/s10482-005-9053-7.
5.2.
2005
Kahru, A.; Drews, M.; Põllumaa, L.; Kasemets, K.; Veidebaum, T.; Kogerman, P. (2005). Toxicity of nanoscale cationic polymers in vitro and in vivo. ALTEX, 22, 302.
1.1.
2004
Pall, T.; Gad, A.; Kasak, L.; Drews, M.; Stromblad, S.; Kogerman, P (2004). Recombinant CD44-HABD is a novel and potent direct angiogenesis inhibitor enforcing endothelial cell-specific growth inhibition independently of hyaluronic acid binding. Oncogene, 23 (47), 7874−7881.
1.1.
2003
Kasemets, K.; Drews, M.; Nisamedtinov, I.; Adamberg, K.; Paalme, T (2003). Modification of A-stat for the characterization of microorganisms. Journal of Microbiological Methods, 55 (1), 187−200.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quasi-steady-state cultures. International Congress on Bioreactor Technology in Cell-, Tissue Culture and Biomedical Applications, 1st, Tampere, Finland 14 - 18 July 2003. Ed. Sorvari, S. BioBien Innovations (BBi), 218−225.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quai-steady-state cultures in laboratory and industrial practice. In: 1st International Congress on Bioreactor Technology in Cell, Tissue Culture and Biomedical Applications : 14–18 July, 2003,Tampere : abstracts (42). . Turku: Karhukopio OY.
1.1.
2000
Drews, M.; Doverskog, M.; Öhman, L.; Chapman, B. E.; Jacobsson, U.; Kuchel, P. W.; Häggström, L. (2000). Pathways of glutamine metabolism in Spodopera frugiperda (Sf9) insect cells: evidence for the presence of the nitrogen assimilation system, and a metabolic switch by 1H/15N NMR. Journal of Biotechnology, 78, 23−37.
2.3.
1999
Drews, M. (1999). A metabolic study of insect cells in batch and continuous culture : application of chemostat and turbidostat to the production of recombinant proteins. (Doktoritöö, Tallinna Tehnikaülikool). Tallinn: TTU Press.
5.2.
1999
Siigur, E.; Tõnismägi, K.; Merits, A.; Drews, M.; Siigur, J. (1999). Expression of fibrinolytic enzyme, lebetase, from Vipera lebetina snake venom by baculovirus system. Toxicon, 37, 305.
1.3.
1998
Drews, M.; Kasemets, K.; Nisamedtinov, I.; Paalme, T. (1998). Continuous cultivation of insect and yeast cells at maximum specific growth rate. Proceedings of the Estonian Academy of Sciences. Chemistry, 47, 175−188.
5.2.
1998
Siigur, E.; Tõnismägi, K.; Merits, A.; Drews, M.; Siigur, J. (1998). Expression of prolebetase from Vipera lebetina by baculovirus system. Plasminogen activating activity of SF-9 cell lysates. Fibrinolysis & Proteolysis, 12 (Suppl. 1), 66.
5.2.
1998
Siigur, E.; Aaspõllu, A.; Tõnismägi, K.; Samel, M.; Drews, M.; Merits, A.; Tu, A.; Siigur, J. (1998). Biochemical characterization, cDNA cloning and expression of the fibrinolytic enzyme. Lebetase from Vipera lebetina venom. Toxicon, 36. 1258.
3.1.
1997
"Drews, Monika;Paalme, Toomas" (1997). Elucidation of metabolism network of mammalian cell line K562 using 2-14 C glucose label and stoichiometric modelling. Proceedings (697−702).. Dordrecht: Kluwer Academic Publishers.
3.1.
1997
Drews, M.; Paalme, T. (1997). Elucidation of metabolic network of mammalian cell line K562 using 2-14C glucose label and stoichiometric modelling. Manuel J. T. Carrondo, Bryan Griffits and Jose L. P. Moreira. Animal Cell Technology: From Vaccines to Genetic Medicine (697−702). . Kluwer Academic Publishers.
3.2.
1997
Drews, M.;Paalme, T.; Vilu, R. (1997). Chemostat culture of Spodoptera frugiperda Sf9 cells: nutrient requirement and baculovirus expression. Karl Maramorosch and Jun Mitsuhashi. Invertebrate cell culture: Novel directions and biotechnology applications (115−122). . Science Publisher.
3.1.
1996
"Drews, Monika;Paalme, Toomas" (1996). Stoichiometric model of metabolism in the mammalian cell line K562 using 2-14C glucose label. Animal Cell Technology. From Vaccines to Genetic Medicine. Proceedings of the 14th Meeting of the ESACT, Vilamoura, Portugal, May 1996: 14th Meeting of the ESACT, Vilamoura, Portugal, May 1996. Ed. Manuel J. T. Carrondo, Bryan Griffiths and Jose L. P. Moreira. Kluwer Academic Publishers, 697−702.
1.1.
1995
Drews, M.; Paalme, T.; Vilu, R. (1995). The growth and nutrient utilization of the insect cell line Spodoptera frugiperda Sf9 cells in batch and continuous culture. Journal of Biotechnology, 40 (3), 187−198.

Tööstusomand

16.11.2020

Monika Drews

https://etis.ee/CV/Monika_Drews/eng
29.06.1967
5596 1592
monika.drews@ttk.ee
MDrewsinee@gmail.com

Career

Institutions and positions
2017–...   
Tallinn Health Care College, Medical Technology Education Centre, Pharmacist Curriculum, Assistant Pharmacist Curriculum Lecturer-teacher (1,00)
2016–2017   
Tallinn Health Care College, lecturer (1,00)
2015–2016   
Tallinn Health Care College, Medical Technology Education Centre, Pharmacist Curriculum, lecturer (0,50)
2009–2014   
Competence Center for Cancer Research, Project coordinator (1.00), cellular immunotherapy (1,00)
2008–2013   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, Chair of Molecular Diagnostics, Senior Researcher (0,25)
2007–2007   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, Chair of Molecular Diagnostics, Extraordinary Senior Researcher (0,25)
2005–2007   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, Chair of Molecular Diagnostics, Extraordinary Senior Researcher (0,25)
2005–2009   
Competence Center for Cancer Research, Project leader, Project:Optimization of bioprocesses for medium scale production of recombinant proteins (1,00)
2002–2005   
National Institute of Chemical Physics and Biophysics, Welcome Trust scientist, Laboratory of Molecular Genetics, cancer research workgroup (1,00)
2000–2002   
National Institute of Chemical Physics and Biophysics, seniour research scientist, Laboratory of Molecular Genetics, cancer research group (1,00)
1996–2000   
National Institute of Chemical Physics and Biophysics, research scientist, Laboratory of Molecular Genetics, microbiology-biotechnology workgroup (1,00)
1991–1996   
National Institute of Chemical Physics and Biophysics, junior research scientist, Laboratory of Molecular Genetics, microbiology - biotechnology workgroup (1,00)
1989–1990   
National Institute of Chemical Physics and Biophysics, research associate, Laboratory of Molecular Genetics, microbiology-biotechnology workgroup (0,50)
 
 
Education
1997–1998   
Royal Institute of Technology, Stockholm, Sweden, visiting Ph.D student, animal cell technology, prof. L. Häggström, Animal Cell Technology research group
1995–1999   
Tallinn Technical University, biotechnology, Ph.D in Natural Sciences
1985–1990   
Tartu University, cum laude, biology - biochemistry, M. Sc
1974–1985   
Tallinn 44th Secondary School, chemistry specialty
 
 
R&D related managerial and administrative work
2018−2019   
THCC institutional acreditation "Assessment analysis" workgroup
2005−2014   
Establishment and leading of cell culture laboratory, Competence Centre for Cancer Research, Tallinn
2005−2009   
Project leader, CCCR
 
 
Additional information
2020 - Course "Library information search (e-course)", Tallinn Health Care College, Tallinn, Estonia (13.04.2020 - 11.05.2020), 26 academic hours, certificate
2019 - Nutrition and Physical Therapy Conference, SA North-Estonian Regional Hospital, Tallinn, Estonia (17.01.2019) 8 hours, 8 advanced training points, certificate
2018 - Medicinal plants in nutrition therapy, Rahvatervise Akadeemia, Tallinn, Estonia (16.11.2018) 26 academic hours, certificate
2018 - Teaching in Higher Education - Skills, Strategies and Opportunities, Tallinn University, Tallinn, Estonia, (08.11.2017 - 31.01.2018), 92 academic hours, certificate
2017 - Course: Nutrition for healthy and diseased, East- Tallinn Central Hospital, Tallinn, Estonia (30.10-31.10.2017), 16 hours (certificate Nr 142/26)
2017 - Course: Nutrition for healthy and diseased, East- Tallinn Central Hospital, Tallinn, Estonia (19.01-20.01.2017) 16 hours (certificate Nr 5/8)
2016 - ILADS (International Lyme and Associated Diseases Society) 6th European Conference, Helsinki, Finland (CME accredited conference) (10 – 11. 06. 2016); CME points awarded by the Faculty of Medicine, University of Helsinki: Infectious Disease 2.0 hours; Clinical Microbiology 2.0 hours; Paediatrics hours and Pathology 5.0 hours, certificate
2015 - Business course, SOK Promstandart, Tallinn, Estonia (28.11.2014 - 30.01. 2015) 160 hours, certificate
2014 - Export course, Instructor: Tõnu Hein, HeiVäl Consulting, Mektory, Tallinn, Estonia (2-10.04.2014) 24 hours, certificate
2012 - NCO Cell Therapy Cluster - GMP training, Regea Cell and Tissue Center BioMediTech, University of Tampere, Finland (10-12.4.2012), certificate
2006 - How to Write a Competitive Proposal for FP7 course, Instructor: Dr. Sean McCarty, Hyperion Ltd., Tallinn, Estonia (28. 11. 2006)
2004 - Project manager course, Tallinn, Estonia (20-21.1. 2004)
2003 - Biomedical Magnetic Resonance course, University of Göteborg, Sweden, January 2003
2001 - Laboratory Animal Science and Techniques, Tallinn University of Technology, Tallinn, Estonia (23.11 - 14.12. 2001), certificate
1997 - Physiology of Industrial Microorganisms course, Royal Institute of Technology, Stockholm, Sweden, 1997
1996 - Animal Cell Technology course, Royal Institute of Technology, Stockholm, Sweden (15-28.4.1996)
1994 - English language course (upper intermediate level), Soros International House, Tallinn, Estonia (5.09 – 23.11. 1994), upper intermediate level certificate
1993 - Animal Cell Technology course, Royal Institute of Technology, Stockholm, Sweden (19-22.4.1993)

Qualifications

Academic degrees
Monika Drews, Doctor's Degree, 1999, (sup) Raivo Vilu, Metabolism of Insect cells in Periodic and Continuous Cultures: Application of Chemostat and Turbidostat Cultivations in Production of Recombinant Proteins, Tallinn University of Technology Faculty of Chemical and Materials Technology.
 
 
Honours & awards
2019, Monika Drews, Student Union's recognition for excellent work in Tallinn Health Care College
1993, Monika Drews, Georg Soros stipend, 1993
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; CERCS CLASSIFICATION: T490 Biotechnology ; SPECIFICATION: Physiology and metabolism of mammalian and insect cell cultures. Development of serum-free media and optimization of cultivation of mammalian producer cell lines. Development of novel supplements for serum-free suspension mammalian cell cultures. The study of in vitro cultivation and activization of human natural killer cells.
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; SPECIFICATION: Biotechnology, metabolism and physiology of industrially important mammalian and insect cell cultures, development and optimization of cultivation methods, the study of recombinant protein and monoclonal antibody processes for development of cancer treatment strategies
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering
 
 
Additional information
Ph.D in Natural Sciences
Tallinn Technical University, 1999

Projects in progress

Completed projects

Supervised dissertations

Publications

Category
Year
Publication
 
1.3.
2020
Drews, Monika (2020). Haigustekitajad Eesti puukides. Väike hammustus võib viia suure probleemini. Apteek Täna, 2, 88−91.
3.2.
2019
Titma, T.; Ruuben, L.; Drews, M. (2019). Compounding, extemporaneous prepare or reconstitution of the radiopharmaceuticals. In: COE EDQM Proceedings of International Conferences, EDQM & European Pharmacopoeia: State-of-the-art Science for Tomorrow’s Medicines. Strasbourg: COE EDQM Publications.
3.5.
2019
Juurmaa, Margit; Vainoja, Ave; Drews, Monika; Parts, Laine (2019). Seleeni sisalduse määramise metoodika välja töötamine ja valideerimine [Seleeni sisalduse määramise metoodika välja töötamine ja valideerimine ]. Tervisevaldkonna uuringute infopäev, Tallinn, Eesti, 1.10.2019. Toim. Angela Ivask. Tervisevaldkonna uuringute infopäev: elektroonselt avaldatud, 9.
6.6.
2019
Drews, Monika (2019). Farmatseutide pere täienes 28 erialaspetsialistiga [Farmatseutide pere täienes 28 erialaspetsialistiga]. Eesti Rohuteadlane, 3, 11.
1.2.
2014
Värv, Kairi; Rumvolt, Reet; Järvekülg, Lilian; Drews, Monika; Ehin, Riin (2014). Potential of In Vitro Expanded NK Cells as a Highly Cytotoxic Tool for Fighting Melanoma. Journal for Clinical Studies, 6 (4), 46−51.
1.2.
2014
Voodla, Karoli; Rumvolt, Reet; Aints, Alar; Drews, Monika (2014). Medical Colloids In Design of Mammalian Serum-Free Media. International Journal of Emerging Trends in Pharmaceutical Sciences, 2 (1), 1−4.
5.2.
2012
Värv, Kairi; Rumvolt, Reet; Drews, Monika (2012). Characterization of human natural killer cell culture by flow cytometry. FACS Users Meeting „Advances in flow cytometry“ November 6-7, Tallinn, 2012. http://inbio.ee/2012/11/16/eesti-facsi-kasutajate-konverents-advances-in-flo,.
3.1.
2010
Drews, Monika; Hunt, Reet (2010). Growth and Production Characteristics of Four Mammalian Cell Lines on a Cost-Effective Serum-Free Medium. In: Cells and Culture (223−227). Springer. DOI: 10.1007/978-90-481-3419-9_38.
3.1.
2010
Voodla, K., Rumvolt, R., Drews, M. (2010). Extract of Selenium-enriched Yeast Enhances Growth and Production Parameters of Mammalian Cell Lines in Serum-free Suspension Cultures. Journal of Biotechnology, 150. , 400. (1). DOI: 10.1016/j.jbiotec.2010.09.522.
5.1.
2010
Voodla, Karoli; Rumvolt, Reet; Drews, Monika (2010). Extract of Selenium-enriched Yeast Enhances Growth and Production Parameters of Mammalian Cell Lines in Serum-free Suspension Cultures. 14th International Biotechnology Symposium and Exhibition. Biotechnology for the Sustainability of Human Society. 14-18 September, Palacongressi, Rimini, Italy 2010, P 1533.. P 1533.
5.1.
2009
Voodla, Karoli; Hunt, Reet; and Drews, Monika (2009). The effect of extract of selenium-enriched yeast on growth of hybridoma and CHO cells. 21th Meeting of the European Society for Animal Cell Technology (ESACT) „Cellular Solutions for Clinical Challenges“, June 7-10, 2009, Dublin, Ireland. Dublin, Ireland, 387.
6.7.
2009
Drews, M., Rumvolt, R., Voodla, K. (2009). PCT WO 2009/149719 A1 The use of extract of selenium enriched yeast (Se-YE) in mammalian cell culture media formulations. In: .. World Intellectual Property Organization.
1.1.
2007
Hunt, R.; Bragina, O.; Drews, M.; Kasak, L.; Timmusk, S.; Valkna, A.; Kogerman, P.; Järvekülg, L. (2007). Generation and Characterization of mouse monoclonal antibody 5E1 against human transcription factor Gli3. Hybridoma, 26 (3), 131−138.
5.1.
2007
Drews, Monika; Hunt, Reet (2007). Growth and production characteristics of four mammalian cell lines on a cost-effective serum-free medium. In: Cells & Culture (3.32).20th Meeting of the European Society for Animal Cell technology (ESACT), June 17-20, 2007, Dresden, Germany.
1.1.
2006
Paalme, Toomas; Nisamedtinov, Ildar; Abner, Kristo; Laht, Tiiu-Maie; Drews, Monika; Pehk, Tõnis (2006). Application of  <SUP>13</SUP>C-[2]- and <SUP>13</SUP>C[1,2] acetate in metabolic labelling studies of yeast and insect cells. Antonie van Leeuwenhoek, 89, 443−457. DOI: 10.1007/s10482-005-9053-7.
5.2.
2005
Kahru, A.; Drews, M.; Põllumaa, L.; Kasemets, K.; Veidebaum, T.; Kogerman, P. (2005). Toxicity of nanoscale cationic polymers in vitro and in vivo. ALTEX, 22, 302.
1.1.
2004
Pall, T.; Gad, A.; Kasak, L.; Drews, M.; Stromblad, S.; Kogerman, P (2004). Recombinant CD44-HABD is a novel and potent direct angiogenesis inhibitor enforcing endothelial cell-specific growth inhibition independently of hyaluronic acid binding. Oncogene, 23 (47), 7874−7881.
1.1.
2003
Kasemets, K.; Drews, M.; Nisamedtinov, I.; Adamberg, K.; Paalme, T (2003). Modification of A-stat for the characterization of microorganisms. Journal of Microbiological Methods, 55 (1), 187−200.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quasi-steady-state cultures. International Congress on Bioreactor Technology in Cell-, Tissue Culture and Biomedical Applications, 1st, Tampere, Finland 14 - 18 July 2003. Ed. Sorvari, S. BioBien Innovations (BBi), 218−225.
5.2.
2003
Drews, M.; Nisamedtinov, I.; Paalme, T. (2003). Application of quai-steady-state cultures in laboratory and industrial practice. In: 1st International Congress on Bioreactor Technology in Cell, Tissue Culture and Biomedical Applications : 14–18 July, 2003,Tampere : abstracts (42). . Turku: Karhukopio OY.
1.1.
2000
Drews, M.; Doverskog, M.; Öhman, L.; Chapman, B. E.; Jacobsson, U.; Kuchel, P. W.; Häggström, L. (2000). Pathways of glutamine metabolism in Spodopera frugiperda (Sf9) insect cells: evidence for the presence of the nitrogen assimilation system, and a metabolic switch by 1H/15N NMR. Journal of Biotechnology, 78, 23−37.
2.3.
1999
Drews, M. (1999). A metabolic study of insect cells in batch and continuous culture : application of chemostat and turbidostat to the production of recombinant proteins. (Doktoritöö, Tallinna Tehnikaülikool). Tallinn: TTU Press.
5.2.
1999
Siigur, E.; Tõnismägi, K.; Merits, A.; Drews, M.; Siigur, J. (1999). Expression of fibrinolytic enzyme, lebetase, from Vipera lebetina snake venom by baculovirus system. Toxicon, 37, 305.
1.3.
1998
Drews, M.; Kasemets, K.; Nisamedtinov, I.; Paalme, T. (1998). Continuous cultivation of insect and yeast cells at maximum specific growth rate. Proceedings of the Estonian Academy of Sciences. Chemistry, 47, 175−188.
5.2.
1998
Siigur, E.; Tõnismägi, K.; Merits, A.; Drews, M.; Siigur, J. (1998). Expression of prolebetase from Vipera lebetina by baculovirus system. Plasminogen activating activity of SF-9 cell lysates. Fibrinolysis & Proteolysis, 12 (Suppl. 1), 66.
5.2.
1998
Siigur, E.; Aaspõllu, A.; Tõnismägi, K.; Samel, M.; Drews, M.; Merits, A.; Tu, A.; Siigur, J. (1998). Biochemical characterization, cDNA cloning and expression of the fibrinolytic enzyme. Lebetase from Vipera lebetina venom. Toxicon, 36. 1258.
3.1.
1997
"Drews, Monika;Paalme, Toomas" (1997). Elucidation of metabolism network of mammalian cell line K562 using 2-14 C glucose label and stoichiometric modelling. Proceedings (697−702).. Dordrecht: Kluwer Academic Publishers.
3.1.
1997
Drews, M.; Paalme, T. (1997). Elucidation of metabolic network of mammalian cell line K562 using 2-14C glucose label and stoichiometric modelling. Manuel J. T. Carrondo, Bryan Griffits and Jose L. P. Moreira. Animal Cell Technology: From Vaccines to Genetic Medicine (697−702). . Kluwer Academic Publishers.
3.2.
1997
Drews, M.;Paalme, T.; Vilu, R. (1997). Chemostat culture of Spodoptera frugiperda Sf9 cells: nutrient requirement and baculovirus expression. Karl Maramorosch and Jun Mitsuhashi. Invertebrate cell culture: Novel directions and biotechnology applications (115−122). . Science Publisher.
3.1.
1996
"Drews, Monika;Paalme, Toomas" (1996). Stoichiometric model of metabolism in the mammalian cell line K562 using 2-14C glucose label. Animal Cell Technology. From Vaccines to Genetic Medicine. Proceedings of the 14th Meeting of the ESACT, Vilamoura, Portugal, May 1996: 14th Meeting of the ESACT, Vilamoura, Portugal, May 1996. Ed. Manuel J. T. Carrondo, Bryan Griffiths and Jose L. P. Moreira. Kluwer Academic Publishers, 697−702.
1.1.
1995
Drews, M.; Paalme, T.; Vilu, R. (1995). The growth and nutrient utilization of the insect cell line Spodoptera frugiperda Sf9 cells in batch and continuous culture. Journal of Biotechnology, 40 (3), 187−198.

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16.11.2020

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ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF7652Funktsionaalsete kasvufaktorite mõju ravimvalkude tootlikkusele imetajarakkudes 01.01.200831.12.2011Monika DrewsVähiuuringute Tehnoloogia Arenduskeskus AS37 196,11 EUR
1.1.3.1.1-14/54Kutsealane eelkoolitus Tallinna Arte Gümnaasiumis23.02.201631.08.2019Siret PiirsaluTallinna Tervishoiu Kõrgkool, Elukestva õppe keskus7 000,00 EUR
1.1.3.1.1-12/109/2019Kutsealane eelkoolitus Tallinna Arte Gümnaasiumis 02.09.201902.09.2024Siret PiirsaluTallinna Tervishoiu Kõrgkool0,00 EUR
1.1.3.1.1-12/13Kutsealase eelkoolituse läbiviimine Tallinna Laagna Gümnaasiumis17.08.201701.07.2020Siret PiirsaluTallinna Tervishoiu Kõrgkool, Elukestva õppe keskus5 880,00 EUR
1.1.3.1.1-12/15Kutsealase eelkoolituse läbiviimine Tallinna Laagna Gümnaasiumis27.03.201401.07.2017Siret PiirsaluTallinna Tervishoiu Kõrgkool, Elukestva õppe keskus13 125,00 EUR
1.; 1.1.; 1.1.3.1.1-12/29/2020Kutsealase eelkoolituse läbiviimine Tallinna Laagna Gümnaasiumis07.09.202001.07.2023Siret PiirsaluTallinna Tervishoiu Kõrgkool5 000,00 EUR
ETFETF6841Oligonukleotiidide kiibil põhineva transkriptsioonifaktorite määramise meetodi väljatöötlus, transkriptsioonifaktorite profileerimine basaalrakulistes kartsinoomides01.01.200631.12.2009Andres ValknaTallinna Tehnikaülikool, Matemaatika-loodusteaduskond27 931,94 EUR
1.; 1.1.; 1.1.3.; 1.1.3.1.8-21/39/2020Tervishoiualase valikaine läbiviimine Peetri Lasteaed-Algkoolis18.09.202001.07.2021Siret PiirsaluTallinna Tervishoiu Kõrgkool1 225,00 EUR
SFSF0140145As08Tuumorprogressiooni molekulaarbioloogia: molekulaarsed mehhanismid ja biomeditsiinilised rakendused01.01.200831.12.2013Andres ValknaTallinna Tehnikaülikool, Matemaatika-loodusteaduskond616 089,84 EUR
SFSF_0222601As03Vähktõve molekulaarbioloogia: molekulaarsed mehhanismid ja biomeditsiinilised rakendused01.01.200331.12.2007Priit KogermanTallinna Tehnikaülikool, Matemaatika-loodusteaduskond0,00 EUR
SFSF0222601As03Vähktõve molekulaarbioloogia: molekulaarsed mehhanismid ja biomeditsiinilised rakendused01.01.200331.12.2007Priit KogermanTallinna Tehnikaülikool, Matemaatika-loodusteaduskond518 195,64 EUR