This website uses cookies to store user session information. By using our website you consent to our terms of use. Read more
I agree

Eva Žusinaite

https://etis.ee/CV/Eva_Žusinaite/eng
17.06.1972
737 4881
eva.zusinaite@ut.ee
http://
G-5520-2019

Career

Institutions and positions
01.01.2021–...   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Associate Professor of Virology (1,00)
1998-2001 - Tartu University, Department of Internal Medicine, research scientist
2001-2002 - Estonian Biocentre, reserach scientist
from 2002 - Tartu University, Institute of Molecular and Cell Biology, research scientist
01.06.2017–31.12.2020   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Research Fellow in Virology (1,00)
01.01.2016–31.05.2017   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Research Fellow in Applied Virology (1,00)
01.06.2014–31.12.2015   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow in Applied Virology (1,00)
01.06.2011–31.05.2014   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow in Applied Virology (1,00)
01.06.2008–31.05.2011   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Research Fellow of Applied Virology (1,00)
01.01.2008–31.05.2008   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Research Fellow extraordinarius (1,00)
01.01.2006–31.12.2007   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, Research Fellow extraordinarius (1,00)
01.01.2004–31.12.2005   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, Research Fellow extraordinarius (1,00)
2002–2006   
University of Tartu, Faculty of Biology and Geography, Extraordinary Researcher (1,00)
 
 
Education
1987-1990 - Tallinn Medical school
1990-1997 - Tartu University, Faculty of Medicine, MD
1997–2003   
1997-2003 - Tartu University, Faculty of Medicine, PhD studies in gastroenterology
 
 
R&D related managerial and administrative work
2014−...   
Global Virus Network conference of virologists for the Scandinavia-Baltic-Ukraine region, 11-13.06.2014, Laulasmaa, Estonia, organizer
2013−...   
Symposium "HCV animal models and vaccine development", organizer
2011−...   
25.04.-05.05.2011. FEBS practical and lecture course "Viral expression vectors for basic and applied studies", TU Institute of Technology, Organizer, tutor
2010−...   
27.09.-02.10.2010. Practical course "Viral vectors: from construction to detection of gene expression", Estonian Biocentre, TU Insitute of Technology; Organizer, tutor
2009−...   
09.-14.11.2009. Practical course "Viral vectors: from construction to detection of gene expression", Estonian Biocentre, TU Institute of Technology; Organizer, tutor
2008−...   
10.-14.11.2009 Practical course "Viral expression vectors for research and biotechnology", Estonian Biocentre, TU Institute of Technology; Organizer, tutor
2007−...   
06.-16.08.2007 FEBS advanced practical and lecture course "Viral expression vectors for research and biotechnology", organizer, tutor
2006−...   
19.06.-21.06.2006 - Symposium “Small DNA and RNA viruses – from basic studies to the development of systems for gene technology applications”, organizer
2004−...   
03.05.-13.05.2004 – “Viral expression vectors for research and biotechnology”, FEBS, Tartu University, Institute of Molecular and Cell Biology, Tartu. Advanced course. Tutor.
2003−...   
26.08.-02.09.2003 –”Virus vectors – expression and detection of recombinant and viral proteinsin infected cells", EU Center of Excellence, Estonian Biocentre, Advanced practical course, Tutor

Qualifications

Academic degrees
Eva Žusinaite, Doctor's Degree, 2005, (sup) Riina Salupere; Vello Salupere, Hepatitis C virus: genotype identification and interactions between viral proteases (Hepatitis C virus: genotype identification and interactions between viral proteases), University of Tartu, Faculty of Medicine, Department of Internal Medicine, Chair of Internal Medicine.
 
 
Additional information
MD
DSc (Medicine)
Tartu University, 1997
Tartu University, 2005

Projects in progress

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2020
Liu, Xiang; Mutso, Margit; Cherkashchenko, Liubov; Zusinaite, Eva; Herrero, Lara J.; Doggett, Stephen L.; Haniotis, John; Merits, Andres; Herring, Belinda L.; Taylor, Adam; Mahalingam, Suresh (2020). Identification of natural molecular determinants of Ross River virus type I IFN modulation. Journal of Virology, 94e. DOI: 10.1128/JVI.01788-19.
1.1.
2020
Elhi, Fred; Priks, Hans; Rinne, Pille; Kaldalu, Niilo; Žusinaite, Eva; Johanson, Urmas; Aabloo, Alvo; Tamm, Tarmo; Põhako-Esko, Kaija (2020). Electromechanically active polymer actuators based on biofriendly choline ionic liquids. Smart Materials and Structures, 29 (5), 055021. DOI: 10.1088/1361-665X/ab7f24.
1.1.
2020
Mutso, Margit; St John, James A.; Ling, Zheng Lung; Burt, Felicity J.; Poo, Yee Suan; Liu, Xiang; Žusinaite, Eva; Grau, Georges E.; Hueston, Linda; Merits, Andres; King, Nicholas J.C.; Ekberg, Jenny A.K.; Mahalingam, Suresh (2020). Basic insights into Zika virus infection of neuroglial and brain endothelial cells. Journal of General Virology. DOI: 10.1099/jgv.0.001416.
1.1.
2019
Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Miia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca J; Tenson, Tanel; Merits, Andres ... Kainov, Denis E (2019). Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018. Viruses, 11 (3), 11(3).10.3390/v11030207.
1.1.
2019
Bösl, K.; Ianevski, A.; Than, T.T.; Andersen, P.I.; Kuivanen, S.; Teppor, M.; Zusinaite, E.; Dumpis, U.; Vitkauskiene, A.; Cox, R.J.; Kallio-Kokko, H.; Bergqvist, A.; Tenson, T.; Merits, A.; Oksenych, V.; Bjørås, M.; Anthonsen, M.W.; Shum, D.; Kaarbø, M.; Vapalahti, O. ... Kandasamy, R.K. (2019). Common nodes of virus–host interaction revealed through an integrated network analysis. Frontiers in Immunology, 10 (2186).10.3389/fimmu.2019.02186.
1.1.
2018
Zusinaite, E.; Ianevski, A.; Niukkanen, D.; Poranen, M.M.; Bjørås, M.; Afset, J.E.; Tenson, T.; Velagapudi, V.; Merits, A.; Kainov, D.E. (2018). A systems approach to study immuno- and neuro-modulatory properties of antiviral agents. Viruses, 10 (8).10.3390/v10080423.
1.1.
2018
Ianevski, Aleksandr; Zusinaite, Eva; Kuivanen, Suvi; Strand, Marten; Lysvand, Hilde; Teppor, Mona; Kakkola, Laura; Paavilainen, Henrik; Laajala, Mira; Kallio-Kokko, Hannimari; Valkonen, Miia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Bjoras, Magnar; Nordbo, Svein Arne; Dumpis, Uga ... Kainov, Denis (2018). Novel activities of safe-in-human broad-spectrum antiviral agents. Antiviral Research, 154, 174−182.10.1016/j.antiviral.2018.04.016.
1.1.
2018
Meutiawati, Febrina; Bezemer, Bodine; Strating, Jeroen R P M; Overheul, Gijs J; Žusinaite, Eva; van Kuppeveld, Frank J M; van Cleef, Koen W R; van Rij, Ronald P (2018). Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein. Antiviral Research, 157, 68−79.10.1016/j.antiviral.2018.06.017.
1.1.
2018
Öhlund, Pontus; García-Arriaza, Juan; Zusinaite, Eva; Szurgot, Inga; Männik, Andres; Kraus, Annette; Ustav, Mart; Merits, Andres; Esteban, Mariano; Liljeström, Peter; Ljungberg, Karl (2018). DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boost. Scientific Reports, 8 (1), 12459−12459.10.1038/s41598-018-31003-6.
1.1.
2017
Mutso, M.; Saul, S.; Rausalu, K.; Susova, O.; Žusinaite, E.; Mahalingam, S.; Merits, A. (2017). Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on Brazilian Zika virus isolate. Journal of General Virology, 98, 2712−2724. DOI: 10.1099/jgv.0.000938.
1.1.
2016
Rausalu, K.; Utt, A.; Quirin, T.; Varghese, F.S.; Žusinaite, E.; Das, P.K.; Ahola, T.; Merits, A. (2016). Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue. Scientific Reports, 6, 37124−37124.10.1038/srep37124.
1.1.
2015
Scholte, F.E.M.; Tas, A.; Albulescu, I.C., Žusinaite, E.; Merits, A.; Snijder, E.J.; van Hemert, M.J. (2015). Stress granule components G3BP1 and G3BP2 play a proviral role early in chikungunya virus replication. Journal of Virology, 89 (8), 4457−4469.10.1128/JVI.03612-14.
1.1.
2015
Mutso, M.; Nikonov, A.; Pihlak, A.; Žusinaite, E.; Viru, L.; Selyutina, A.; Reintamm, T.; Kelve, M.; Saarma, M.; Karelson, M.; Merits, A. (2015). RNA interference-guided targeting of hepatitis C virus replication with antisense locked nucleic acid-based oligonucleotides containing 8-oxo-dG modifications. PLoS ONE, 10 (6), xUNSP e0128686. DOI: 10.1371/journal.pone.0128686.
1.1.
2014
Ustinova, J.; Zusinaite, E.; Utt, M.; Metsküla, K.; Reimand, K.; Huchaiah, V.; Merits, A.; Uibo, R. (2014). Development of a luciferase-based system for detection of ZnT8 autoantibodies. Journal of Immunological Methods, 405, 67−73.10.1016/j.jim.2014.01.009.
1.1.
2011
Ausmees, K.; Selyutina, A.; Kütt, K.; Lippur, K.; Pehk, T.; Lopp, M.; Žusinaite, E.; Merits, A.; Kanger, T. (2011). Synthesis and biological activity of bimorpholine and its carbanucleoside. Nucleosides Nucleotides & Nucleic Acids, 30 (11), 897−907.10.1080/15257770.2011.621919.
1.1.
2010
Karo-Astover, L.; Šarova, O.; Merits, A.; Žusinaite, E. (2010). The infection of mammalian and insect cells with SFV bearing nsP1 palmitoylation mutations. Virus Research, 153 (2), 277−287.
1.1.
2010
Paju, A.; Päri, M.; Selyutina, A.; Zusinaite, E.; Merits, A.; Pehk, T.; Siirde, K.; Müürisepp, A.M.; Kailas, T.; Lopp, M. (2010). Synthesis of novel acyclic nucleoside analogues with anti-retroviral activity. Nucleosides Nucleotides & Nucleic Acids, 29 (9), 707−720.10.1080/15257770.2010.501776.
1.1.
2010
Varjak, M., Žusinaite, E.; Merits, A. (2010). Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. Journal of Virology, 84, 2352−2364.10.1128/JVI.01540-09.
1.1.
2008
Kiiver, K.; Tagen, I.; Zusinaite, E.; Tamberg, N.; Fazakerley, J.; Merits, A. (2008). Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication. Journal of General Virology, 89, 1457−1466. DOI: 10.1099/vir.0.2008/000299-0.
1.1.
2007
Zusinaite, E.; Tints, K.; Kiiver, K.; Spuul, P.; Karo-Astover, L.; Merits, A.; Sarand, I. (2007). Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. Journal of General Virology, 88 (7), 1977−1985. DOI: 10.1099/vir.0.82865-0.
1.1.
2006
Kiiver, K.; Merits, A.; Ustav, M.; Žusinaite, E. (2006). Complex formation between hepatitis C virus NS2 and NS3 proteins. Virus Research, 117 (2), 264−272.
1.1.
2005
Zusinaite, E.; Metsküla, K.; Salupere, R. (2005). Autoantibodies and hepatitis C virus genotypes in chronic hepatitis C patients in Estonia. World Journal of Gastroenterology, 11 (4), 488−491.
1.1.
2000
Zusinaite, E.; Krispin, T.; Raukas, E.; Kiiver, K.; Salupere, R.; Ott, K.; Ustina, V.; Zilmer, K.; Schmidt, J.; Sizemski, L.; Jaago, K.; Luman, M.; Ilmoja, M.; Prukk, T.; Ustav, M. (2000). Hepatitis C virus genotypes in Estonia. APMIS, 108 (11), 739−746.

Industrial property

30.12.2020

Eva Žusinaite

https://etis.ee/CV/Eva_Žusinaite/est
17.06.1972
737 4881
eva.zusinaite@ut.ee
G-5520-2019

Teenistuskäik

Töökohad ja ametid
01.01.2021–...   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, viroloogia kaasprofessor (1,00)
1998-2001 - Tartu Ülikooli Sisekliinik, erakorraline teadur
2001-2002 – Eesti Biokeskus, erakorraline teadur
alates 2002 – Tartu Ülikool, Molekulaar- ja Rakubioloogia Instituut, erakorraline teadur
01.06.2017–31.12.2020   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, viroloogia vanemteadur (1,00)
01.01.2016–31.05.2017   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, rakendusviroloogia vanemteadur (1,00)
01.06.2014–31.12.2015   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, rakendusviroloogia vanemteadur (1,00)
01.06.2011–31.05.2014   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, rakendusviroloogia vanemteadur (1,00)
01.06.2008–31.05.2011   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, rakendusviroloogia teadur (1,00)
01.01.2008–31.05.2008   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, rakendusviroloogia erakorraline teadur (1,00)
01.01.2006–31.12.2007   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, erakorraline teadur (1,00)
01.01.2004–31.12.2005   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, erakorraline teadur (1,00)
2002–2006   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Erakorraline teadur (1,00)
 
 
Haridustee
1987-1990 - Tallinna Meditsiinikool
1990-1997 - Tartu Ülikool, arstiteaduskond
1997–2003   
1997-2003 - Tartu Ülikool, arstiteaduskond, doktorantuur gastroenteroloogia erialal
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2014−...   
Rahvusvaheline konverents "Global Virus Network conference of virologists for the Scandinavia-Baltic-Ukraine region" 11-13.06.2014, Laulasmaa, Estonia, korraldaja
2013−...   
Rahvusvaheline sümpoosium "HCV animal models and vaccine development", korraldaja
2011−...   
25.04.-05.05.2011. FEBS praktiline ja lonegukursus "Viral expression vectors for basic and applied studies", TÜ Tehnoloogiainstituut, Korraldaja, tuutor
2010−...   
27.09.-02.10.2010. Praktiline kursus "Viral vectors: from construction to detection of gene expression", Eesti Biokeskus, TÜ Tehnoloogiainsituut; Korraldaja, tuutor
2009−...   
09.-14.11.2009. Praktiline kursus "Viral vectors: from construction to detection of gene expression", Eesti Biokeskus, TÜ Tehnoloogiainstituut; Korraldaja, tuutor
2008−...   
10.-14.11.2009 Praktiline kursus "Viral expression vectors for research and biotechnology", Eesti Biokeskus, TÜ Tehnoloogiainstituut; Korraldaja, tuutor
2007−...   
06.-16.08.2007 FEBS praktiline ja loengukursus "Viral expression vectors for research and biotechnology", korraldaja, tuutor
2006−...   
19.06.-21.06.2006 - Sümpoosium “RNA ja väikestel DNA viirustel põhinevate biotehnoloogiliste ja terapeutiliste süsteemide loomine ja arendamine”. Korraldaja
2004−...   
03.05.-13.05.2004 – “Viral expression vectors for research and biotechnology”, FEBS, Tartu Ülikooli Molekulaar- ja Rakubiloogia Instituut, Tartu. Praktiline kursus. Osalemine läbiviimisel.
2003−...   
26.08.-02.09.2003 –”Virus vectors – expression and detection of recombinant and viral proteins in infected cells", EU Tippkeskus, Eesti Biokeskus, Tartu, Praktiline kursus, Tuutor

Kvalifikatsioon

Teaduskraadid
Eva Žusinaite, Doctor's Degree, 2005, (sup) Riina Salupere; Vello Salupere, Hepatitis C virus: genotype identification and interactions between viral proteases (Hepatitis C virus: genotype identification and interactions between viral proteases), University of Tartu, Faculty of Medicine, Department of Internal Medicine, Chair of Internal Medicine.
 
 
Lisainfo
MD
DSc (meditsiin)
Tartu Ülikool, 1997
Tartu Ülikool, 2005

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2020
Liu, Xiang; Mutso, Margit; Cherkashchenko, Liubov; Zusinaite, Eva; Herrero, Lara J.; Doggett, Stephen L.; Haniotis, John; Merits, Andres; Herring, Belinda L.; Taylor, Adam; Mahalingam, Suresh (2020). Identification of natural molecular determinants of Ross River virus type I IFN modulation. Journal of Virology, 94e. DOI: 10.1128/JVI.01788-19.
1.1.
2020
Elhi, Fred; Priks, Hans; Rinne, Pille; Kaldalu, Niilo; Žusinaite, Eva; Johanson, Urmas; Aabloo, Alvo; Tamm, Tarmo; Põhako-Esko, Kaija (2020). Electromechanically active polymer actuators based on biofriendly choline ionic liquids. Smart Materials and Structures, 29 (5), 055021. DOI: 10.1088/1361-665X/ab7f24.
1.1.
2020
Mutso, Margit; St John, James A.; Ling, Zheng Lung; Burt, Felicity J.; Poo, Yee Suan; Liu, Xiang; Žusinaite, Eva; Grau, Georges E.; Hueston, Linda; Merits, Andres; King, Nicholas J.C.; Ekberg, Jenny A.K.; Mahalingam, Suresh (2020). Basic insights into Zika virus infection of neuroglial and brain endothelial cells. Journal of General Virology. DOI: 10.1099/jgv.0.001416.
1.1.
2019
Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Miia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca J; Tenson, Tanel; Merits, Andres ... Kainov, Denis E (2019). Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018. Viruses, 11 (3), 11(3).10.3390/v11030207.
1.1.
2019
Bösl, K.; Ianevski, A.; Than, T.T.; Andersen, P.I.; Kuivanen, S.; Teppor, M.; Zusinaite, E.; Dumpis, U.; Vitkauskiene, A.; Cox, R.J.; Kallio-Kokko, H.; Bergqvist, A.; Tenson, T.; Merits, A.; Oksenych, V.; Bjørås, M.; Anthonsen, M.W.; Shum, D.; Kaarbø, M.; Vapalahti, O. ... Kandasamy, R.K. (2019). Common nodes of virus–host interaction revealed through an integrated network analysis. Frontiers in Immunology, 10 (2186).10.3389/fimmu.2019.02186.
1.1.
2018
Zusinaite, E.; Ianevski, A.; Niukkanen, D.; Poranen, M.M.; Bjørås, M.; Afset, J.E.; Tenson, T.; Velagapudi, V.; Merits, A.; Kainov, D.E. (2018). A systems approach to study immuno- and neuro-modulatory properties of antiviral agents. Viruses, 10 (8).10.3390/v10080423.
1.1.
2018
Ianevski, Aleksandr; Zusinaite, Eva; Kuivanen, Suvi; Strand, Marten; Lysvand, Hilde; Teppor, Mona; Kakkola, Laura; Paavilainen, Henrik; Laajala, Mira; Kallio-Kokko, Hannimari; Valkonen, Miia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Bjoras, Magnar; Nordbo, Svein Arne; Dumpis, Uga ... Kainov, Denis (2018). Novel activities of safe-in-human broad-spectrum antiviral agents. Antiviral Research, 154, 174−182.10.1016/j.antiviral.2018.04.016.
1.1.
2018
Meutiawati, Febrina; Bezemer, Bodine; Strating, Jeroen R P M; Overheul, Gijs J; Žusinaite, Eva; van Kuppeveld, Frank J M; van Cleef, Koen W R; van Rij, Ronald P (2018). Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein. Antiviral Research, 157, 68−79.10.1016/j.antiviral.2018.06.017.
1.1.
2018
Öhlund, Pontus; García-Arriaza, Juan; Zusinaite, Eva; Szurgot, Inga; Männik, Andres; Kraus, Annette; Ustav, Mart; Merits, Andres; Esteban, Mariano; Liljeström, Peter; Ljungberg, Karl (2018). DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boost. Scientific Reports, 8 (1), 12459−12459.10.1038/s41598-018-31003-6.
1.1.
2017
Mutso, M.; Saul, S.; Rausalu, K.; Susova, O.; Žusinaite, E.; Mahalingam, S.; Merits, A. (2017). Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on Brazilian Zika virus isolate. Journal of General Virology, 98, 2712−2724. DOI: 10.1099/jgv.0.000938.
1.1.
2016
Rausalu, K.; Utt, A.; Quirin, T.; Varghese, F.S.; Žusinaite, E.; Das, P.K.; Ahola, T.; Merits, A. (2016). Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue. Scientific Reports, 6, 37124−37124.10.1038/srep37124.
1.1.
2015
Scholte, F.E.M.; Tas, A.; Albulescu, I.C., Žusinaite, E.; Merits, A.; Snijder, E.J.; van Hemert, M.J. (2015). Stress granule components G3BP1 and G3BP2 play a proviral role early in chikungunya virus replication. Journal of Virology, 89 (8), 4457−4469.10.1128/JVI.03612-14.
1.1.
2015
Mutso, M.; Nikonov, A.; Pihlak, A.; Žusinaite, E.; Viru, L.; Selyutina, A.; Reintamm, T.; Kelve, M.; Saarma, M.; Karelson, M.; Merits, A. (2015). RNA interference-guided targeting of hepatitis C virus replication with antisense locked nucleic acid-based oligonucleotides containing 8-oxo-dG modifications. PLoS ONE, 10 (6), xUNSP e0128686. DOI: 10.1371/journal.pone.0128686.
1.1.
2014
Ustinova, J.; Zusinaite, E.; Utt, M.; Metsküla, K.; Reimand, K.; Huchaiah, V.; Merits, A.; Uibo, R. (2014). Development of a luciferase-based system for detection of ZnT8 autoantibodies. Journal of Immunological Methods, 405, 67−73.10.1016/j.jim.2014.01.009.
1.1.
2011
Ausmees, K.; Selyutina, A.; Kütt, K.; Lippur, K.; Pehk, T.; Lopp, M.; Žusinaite, E.; Merits, A.; Kanger, T. (2011). Synthesis and biological activity of bimorpholine and its carbanucleoside. Nucleosides Nucleotides & Nucleic Acids, 30 (11), 897−907.10.1080/15257770.2011.621919.
1.1.
2010
Karo-Astover, L.; Šarova, O.; Merits, A.; Žusinaite, E. (2010). The infection of mammalian and insect cells with SFV bearing nsP1 palmitoylation mutations. Virus Research, 153 (2), 277−287.
1.1.
2010
Paju, A.; Päri, M.; Selyutina, A.; Zusinaite, E.; Merits, A.; Pehk, T.; Siirde, K.; Müürisepp, A.M.; Kailas, T.; Lopp, M. (2010). Synthesis of novel acyclic nucleoside analogues with anti-retroviral activity. Nucleosides Nucleotides & Nucleic Acids, 29 (9), 707−720.10.1080/15257770.2010.501776.
1.1.
2010
Varjak, M., Žusinaite, E.; Merits, A. (2010). Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. Journal of Virology, 84, 2352−2364.10.1128/JVI.01540-09.
1.1.
2008
Kiiver, K.; Tagen, I.; Zusinaite, E.; Tamberg, N.; Fazakerley, J.; Merits, A. (2008). Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication. Journal of General Virology, 89, 1457−1466. DOI: 10.1099/vir.0.2008/000299-0.
1.1.
2007
Zusinaite, E.; Tints, K.; Kiiver, K.; Spuul, P.; Karo-Astover, L.; Merits, A.; Sarand, I. (2007). Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. Journal of General Virology, 88 (7), 1977−1985. DOI: 10.1099/vir.0.82865-0.
1.1.
2006
Kiiver, K.; Merits, A.; Ustav, M.; Žusinaite, E. (2006). Complex formation between hepatitis C virus NS2 and NS3 proteins. Virus Research, 117 (2), 264−272.
1.1.
2005
Zusinaite, E.; Metsküla, K.; Salupere, R. (2005). Autoantibodies and hepatitis C virus genotypes in chronic hepatitis C patients in Estonia. World Journal of Gastroenterology, 11 (4), 488−491.
1.1.
2000
Zusinaite, E.; Krispin, T.; Raukas, E.; Kiiver, K.; Salupere, R.; Ott, K.; Ustina, V.; Zilmer, K.; Schmidt, J.; Sizemski, L.; Jaago, K.; Luman, M.; Ilmoja, M.; Prukk, T.; Ustav, M. (2000). Hepatitis C virus genotypes in Estonia. APMIS, 108 (11), 739−746.

Tööstusomand

30.12.2020

Search project

  • {{item.Name}}
Institution is projects' financier   Institution is projects' executor  
  • {{searchListItem.Name}}
All   Projects   Master projects   Subprojects  
New Frascati (2015)
Old and new Frascati
All
Ongoing
Finished
Beginning
Fuzzy
Precise
Simple Search Clear
  • Found 13 results
ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
ETFETF9421Probing the macromolecular architecture of alphavirus replication complex using mutational scanning of protein surfaces, homologous domain swapping and crosslink/ms analyses01.01.201231.12.2014Valeria LullaUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu36 000,00 EUR
ETFETF7407Alphavirus replication, inhibition and virus-host interactions.01.01.200831.12.2011Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old)66 495,46 EUR
ETFETF7501Restriction of alphaviral replication using viral self-downregulation mechanisms01.01.200831.12.2009Valeria LullaUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu37 580,04 EUR
PRGPRG1154Role of arbovirus replicase proteins in RNA replication, virus-host interactions and vector transmission01.01.202131.12.2025Andres MeritsUniversity of Tartu, Faculty of Science and Technology, Institute of Technology257 125,00 EUR
MUUMBGMR06192FEBS Advanced Practical and lecture course "Viral expression vectors for research and biotechnology"20.10.200631.12.2007Eva ŽusinaiteUniversity of Tartu63 761,14 EUR
MUUMLOTI10201FEBS practical course „Viral Expression Vectors for Basic and Applied Studies"01.11.201031.12.2011Eva ŽusinaiteUniversity of Tartu; University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu41 699,99 EUR
TKSLTTI16143T (TK143)Center of Excellence in Molecular Cell Engineering (TK143)01.01.201601.03.2023Tanel TensonUniversity of Tartu, Faculty of Science and Technology, Institute of Technology3 917 568,00 EUR
SFSF0180087s08Analysis of the replication, viral-host interactions and virus induce pathogenesis of viruses with RNA genomes and inhibition or practical usage of these processes.01.01.200831.12.2013Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu653 945,96 EUR
SFSF0182566Bs03Study of the replication mechanisms of RNA and DNA viruses and development of new methods for gene therapy and gene vaccination B01.01.200331.12.2007Mart UstavUniversity of Tartu, Faculty of Biology and Geography309 651,94 EUR
2.2.1.VLTTI20265Development of genetically attenuated vaccine candidates for SARS-CoV-204.05.202031.12.2020Andres MeritsUniversity of Tartu, Faculty of Science and Technology, Institute of Technology80 000,00 EUR
ETFETF6609Mechanisms involved in the Semliki Forest virus replication and virus-host interactions: basic studies and potential use for gene technology.01.01.200631.12.2007Andres MeritsUniversity of Tartu, Faculty of Biology and Geography23 291,96 EUR
COVSGCOVSG2Universal treatment method for antiviral protection of hard to clean surfaces01.11.202031.12.2021Angela IvaskUniversity of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology200 000,00 EUR
IUTIUT20-27Interaction between virus and host: expanding knowledge for the development of biomedical tools01.01.201431.12.2019Andres MeritsUniversity of Tartu, Faculty of Science and Technology, Institute of Technology2 341 200,00 EUR