See veebileht kasutab küpsiseid kasutaja sessiooni andmete hoidmiseks. Veebilehe kasutamisega nõustute ETISe kasutustingimustega. Loe rohkem
Olen nõus

Marika Mikelsaar

https://etis.ee/CV/Marika_Mikelsaar/est
12.11.1938
737 4179
503 9989
marika.mikelsaar@ut.ee
16.05.1993−16.05.2016 Mikelsaar, Marika

Teenistuskäik

Töökohad ja ametid
01.03.2021–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, projekti teadusjuht (0,25)
01.02.2016–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, mikrobioloogia osakond, projekti teadusjuht (0,50)
2010–...   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, Erakorraline juhtivteadur (1,00)
2003–...   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, Emeriitprofessor (1,00)
1965-1968 aspirantuur TRÜ mikrobioloogia kateeder
Muu ...
01.12.2017–28.02.2021   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, projekti teadusjuht (0,30)
01.01.2016–31.01.2016   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, projekti teadusjuht (1,00)
09.02.2013–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, projekti teadusjuht (1,00)
09.02.2010–08.02.2013   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, meditsiinilise biotehnoloogia juhtivteadur (1,00)
09.02.2007–08.02.2010   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, meditsiinilise biotehnoloogia erakorraline professor (1,00)
09.02.2004–08.02.2007   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, meditsiinilise biotehnoloogia erakorraline professor (1,00)
1993–2003   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, Professor (1,00)
01.01.1991–31.12.1993   
Maarjamõisa Haigla
1979–1993   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, Vanemteadur (1,00)
1969–1979   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, Teadur (1,00)
 
 
Haridustee
kõrgem
Tartu ülikool, Arstiteaduskond 1963.
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
1995- 1999 TÜ Meditsiini kraadinõukogu sekretär
2008−2010   
Inimese mikroobiökoloogia ühing tervise ja haiguse korral (rahvusvaheline) , valitud-president
1993−2003   
Mikrobioloogia instituudi juhataja
1993−2003   
Arstiteaduskonna nõukogu liige

Kvalifikatsioon

Teaduskraadid
Marika Mikelsaar, doktorikraad, 1993, (juh) -, Evaluation of the microbial ecosystem in health and disease (Mikrobiaalse ökosüsteemi hindamine tervise ja haiguse korral), Tartu Ülikool, Mikrobioloogia instituut.
 
 
Teaduspreemiad ja tunnustused
2011, Marika Mikelsaar, Tartu Aukodanik
2010, Marika Mikelsaar, EV teaduspreemia elutöö eest
2008, Marika Mikelsaar, Ülemaailmne naisleidurite ja innovaatorite auhind kuldmedal L-Koreas
2008, Marika Mikelsaar, Valgetähe III klassi orden
2007, Marika Mikelsaar, Euroopa Liidu Naisleidurite ja innovaatorite võrgustiku auhind
2007, Marika Mikelsaar, Tartu medal
2002, Marika Mikelsaar, Riigi teaduspreemia meditsiinis
1994, Marika Mikelsaar, Riigi teaduspreemia meditsiinis
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.2. Mikrobioloogia; TÄPSUSTUS: Inimese mikroobiökoloogia tervise ja haiguste korral ja mikrofloora mõju korrigeerimine probiootikutega
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.2. Mikrobioloogia; TÄPSUSTUS: Kliiniline mikrobioloogia
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.1. Biomeditsiin; TÄPSUSTUS: Inimese mikroobiökoloogia , kroonilised põletikulised protsessid, profülaktika ja ravi toetamine probiootikutega
 
 
Lisainfo
meditsiinikandidaat
meditsiinidoktor
Tartu Riiklik Ülikool, 1969
Tartu Ülikool, 1993

Jooksvad projektid

Lõppenud projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2021
Mikelsaar, Marika; Mändar, Reet. (2021). Commentary: Gut Microbiome and Space Travelers' Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions. Frontiers in Physiology, x. DOI: 10.3389/fphys.2021.651977 [ilmumas].
5.2.
2021
Ehrlich-Peets, Kersti; Rätsep, Merle; Vallas, Mirjam; Mikelsaar, Marika; Zilmer, Mihkel; Songisepp, Epp (2021). Probiotic multifunctional Lactobacillus plantarum strain Inducia® for food valorisation and health. FoodBalt 2021: Book of abstracts: 14th Baltic Conference on Food Science and Technology FoodBalt 2021 “Sustainable Food for Conscious Consumer”. Center of Food and Fermentation Technologies, 21−21.
1.1.
2020
Marika Mikelsaar, Jelena Stsepetova, Raik-Hiio Mikelsaar, Kai Truusalu, Imbi Smidt, Pirje Hütt, Merle Rätsep, Epp Songisepp (2020). Polyamines of human strain Lactobacillus plantarum Inducia induce modulation of innate immune markers. Journal of Functional Foods, 72, 1−9. DOI: 10.1016/j.jff.2020.104064.
1.3.
2020
Ainsaar, M.; Soidla, I.; Sepp, E.; Kõljalg, S.; Štšepetova,J.; Rööp, T.; Smidt, I.; Mikelsaar, M.; Mändar, R. (2020). Kelle poole pöördub abi saamiseks Eesti 100-aastane? Sotsiaaltöö, 3.
1.3.
2019
Mikelsaar, Marika; Lõivukene, Krista; Naaber, Paul; Mändar, Reet (2019). Helicobacter pyllori infektsioonide teaduspõhine diagnostika ja mikroobivastane ravi. Eesti Arst, 98 (7), 381−384.
5.2.
2019
Smidt, Imbi; Sepp, Epp; Hoidmets, Dagmar; Rööp, Tiiu; Mikelsaar, Marika; Mändar, Reet (2019). Probiootikumide selekteerimine nahainfektsioonide profülaktikaks. Eesti Arst, 98: Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2019. Eesti Arst, 34−34.
1.1.
2018
Sepp, Epp; Smidt, Imbi; Stsepetova, Jelena; Roop, Tiiu; Hutt, Pirje; Ratsep, Merle; Mikelsaar, Marika (2018). The effect of Lactobacillus fermentum ME-3 on the intestinal microbiota and urine polyamines content: A double-blind placebo-controlled pilot trial. Journal of Functional Foods, 48, 430−438. DOI: 10.1016/j.jff.2018.04.053.
1.3.
2018
Mändar, Reet; Mändar, Hugo; Rööp, Tiiu; Mikelsaar, Marika. (2018). Inimese mikrobioota biopank Tartu Ülikoolis. Eesti Arst, 97 (3), 170−172.
1.3.
2018
Mikelsaar, Marika (2018). Uut probiootikumidest. Perearst, 2, 25−30.
1.1.
2017
Rätsep M.; Kõljalg S.; Sepp E.; Smidt I.; Truusalu K.; Songisepp E.; Stsepetova J.; Naaber P.; Mikelsaar R.H.; Mikelsaar M. (2017). A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection. Anaerobe, 47, 94−103. DOI: 10.1016/j.anaerobe.2017.03.019.
2.4.
2017
Lutsar, Irja; Mändar, Reet; Mikelsaar, Marika; Karki, Tõnis; Brilene, Tatjana; Kõljalg, Siiri; Meriste, Sirli; Sepp, Epp; Avi, Radko; Truusalu, Kai; Parm, Ülle (2017). Meditsiiniline Mikrobioloogia. Üldmikrobioloogia. Tartu: TÜ kirjastus.
3.2.
2017
Mikelsaar, M. (2017). Teadmiste spiraal. Sajand inimese mikroobiökoloogiat Tartu Ülikoolis. Lea Leppik (Toim.). Tartu Ülikooli ajaloo küsimusi XLV. Muutuste sajand Eesti meditsiinis. (102-117.). Tartu: Tartu Ülikooli muuseum.
3.2.
2017
Maaroos, H-I.; Mikelsaar, M.; Vorobjova,T. (2017). Helicobacter pylori avastamise lugu: kliinilised, immunoloogilised ja mikrobioloogilised aspektid. Eesti uurijate panus Nobeli auhinnaga pärjatud uuringutesse. Lea Leppik (Toim.). Muutuste sajand Eesti meditsiinis (76−101). Tartu Ülikooli Kirjastus.
1.1.
2016
Andersen, KK.; Strokappe, NM.; Hultber1, A.; Truusalu, K.; Smidt, I.; Mikelsaar, RH.; Mikelsaar, MM.; Verrips, T.; Hammarström, L.; Marcotte, H. (2016). Neutralization of Clostridium difficile toxin B mediated by engineered lactobacilli producing single domain antibodies. Infection and Immunity, 84 (2), 395−406. DOI: 10.1128/IAI.00870-15.
3.1.
2016
Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena; Songisepp, Epp; Mändar, Reet. (2016). Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population. Advances in Experimental Medicine and Biology, 932, 1−64. DOI: 10.1007/5584_2016_3.
1.1.
2015
Le Roy, Caroline; Štšepetova, Jelena; Sepp, Epp; Songisepp, Epp; Claus, Sandrine; Mikelsaar, Marika. (2015). New insights into the inpact of Lactobacillus population on host-bacteria metabolic interplay. Oncotarget, 6 (31), 1−12. DOI: 10.18632/oncotarget.5906.
1.1.
2015
Hütt, Pirje; Songisepp, Epp; Rätsep, Merle; Mahlapuu, Riina; Kilk, Kilk; Mikelsaar, Marika. (2015). Impact of probiotic L. plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults. Beneficial Microbes, 6 (3), 1−12. DOI: 10.3920/BM2014.0035.
1.2.
2015
Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena; Hütt, Pirje; Zilmer, Kersti; Kullisaar, Tiiu; Zilamer, Mihkel. (2015). Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults. BMC Nutrition, 1 (27), 1−13. DOI: 10.1186/s40795-015-0020-z.
5.2.
2015
Truusalu, Kai; Vainumäe, Inga; Stsepetova, Jelena; Smidt, Imbi; Sepp, Epp; Mikelsaar, Marika; Kõljalg, Siiri (2015). The impact of the initial antibiotic treatment to subsequent recurrences in childhood urinary tract infection caused by Escherichia coli: beta-lactams vs gentamicin. In: . ECCMID 2015 Copenhagen, Denmark, 25-28 April 2015. ECCMID 2015 Copenhagen, Denmark, 25-28 April 2015.
5.2.
2015
Štšepetova Jelena;  Šebunova Natalja; Larionova Anneli; Voor Tiia; Rööp Tiiu;  Mikelsaar Maarika; Mändar Reet; Sepp Epp  (2015). "Quantitative changes of Clostridium sp.in human intestinal tract of different age groups.“. FEMS konverents, Maastricht, Holland, 07.06. – 11.06.2015. FEMS.
5.2.
2015
Šebunova, Natalja;  Larionova, Anneli; Voor, Tiia; Rööp, Tiiu;  Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena (2015). "Molecular quantitative analysis of human intestinal microbiota in different age groups.". 2nd Microbiome R&D and Business Collaboration Forum: Europe. London, UK, 07.05. – 08.05.2015. Global Engage.
1.1.
2014
Kõljalg, Siiri; Truusalu, Kai; Štšepetova, Jelena; Pai, Kristiine; Vainumäe, Inga; Sepp, Epp; Mikelsaar, Marika (2014). The Escherichia coli phylogenetic group B2 with integrons prevails in childhood recurrent urinary tract infections. Apmis, 122 (5), 452−458. DOI: 10.1111/apm.12167.
1.1.
2014
Talja, Ija; Kubo, Anna-Liisa; Veijola, Riitta; Knip, Mikael; Simell, Olli; Ilonen, Jorma; Vaha-Makila, Mari; Sepp, Epp; Mikelsaar, Marika; Utt, Meeme; Uibo, Raivo (2014). Antibodies to Lactobacilli and Bifidobacteria in Young Children with Different Propensity to Develop Islet Autoimmunity. Journal of Immunology Research, ARTN 325938. DOI: 10.1155/2014/325938.
5.1.
2014
Truusalu, K; Smidt, I; Hütt, P; Stsepetova, J; Vainumäe, I; Sepp, E; Mikelsaar, M; Kõljalg, S. (2014). Comparison of phylogenetic groups, antibacterial resistance and integron containment of Escherichia coli from initial episode of childhood urinary tract infections with different outcomes. 24th European Congress of Clinical Microbiology and Infectious Diseases in Barcelona, Spain, 10 – 13 May 2014.. x, x.
5.2.
2014
Štšepetova, Jelena; Oopkaup, Helen; Smidt, Imbi; Mikelsaar, Marika. (2014). The ability of intestinal Lactobacillus sp.to produce putrescine from agmatine. The Intestinal Microbiota and Gut Health: Contribution of the Diet, Bacterial Metabolites, Host Interactions and Impact on Health and Disease. x, 171−173.
5.2.
2014
Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika; Mändar, Reet. (2014). Human Microbiota Biobank. 2nd World Congress on Targeting Microbiota, Institut Pasteur, Paris, France, October 16-17, 2014..
5.2.
2014
Mändar, Reet; Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika. (2014). Microbiota Collection at University of Tartu: Human Microbiota Biobank (HUMB). International Scientific Conference on Probiotics and Prebiotics - IPC2014, Budapest, Hungary, 24 – 26 June, 2014.
5.2.
2014
Štšepetova, J.; Šebunova, N.; Larionova, A.; Voor, T.; Rööp, T.; Mikelsaar, M.; Sepp, E. (2014). c. 2014 ENGIHR Conference: The Gut Microbiota Throughout Life, Max Rubner-Insitut, Karlsruhe, Germany, September 24-26, 2014.
5.2.
2014
Hütt, P., Sepp, E.; Truusalu, K.; Kullisaar, T.; Zilmer, K.; Zilmer, M.; Mikelsaar, M. (2014). Effect of consumption of probiotic kefir comprising Lactobacillus fermentum strain ME-3 on blood indices of healthy volunteers. ECCMID - European Congress on Clinical Microbiology and Infectious Diseases; Barcelona, Spain; May 10-13, 2014.
5.2.
2014
Štšepetova Jelena; Šebunova Natalja; Larionova Anneli; Voor Tiia; Rööp Tiiu; Mikelsaar Maarika; Sepp Epp. (2014). "Quantitative changes of Lactobacillus and Bifidobacterium sp. in human intestinal tract of different age groups.". The European Network for Gastrointestinal Health Research), Karlsruhe, Germany, 24.09–26.09.2014.. http://www.engihr.eu/2014-engihr-conference/: Max Rubner Institute.
1.1.
2013
Sharafedtinov, Khaider; Plotnikova, Oksana; Alexeeva, Ravilay; Sentsova, Tatjana; Songisepp, Epp; Stsepetova, Jelena; Smidt, Imbi; Mikelsaar, Marika (2013). Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study. Nutrition Journal, 12, 138−159. DOI: 10.1186/1475-2891-12-138.
5.2.
2013
Štšepetova, J; Oopkaup, H; Smidt, I; Mikelsaar, M. (2013). The ability of intestinal Lactobacillus sp. to produce putrescine from agmatine. European Network for gastrointestinal health research: The intaestinal Microbiota and Gut Health: Contribution of the Diet, Bacterial Metabolites, Host interactions and Impact on Health and Diseases. x, 171−173.
6.3.
2013
Leppik, Lea; Mikelsaar, Marika (2013). Kosmonaudid, laktobatsillid ja Tartu. Horisont, 3, 47−48.
1.1.
2012
Songisepp, E.; Hütt, P.; Rätsep, M.; Shkut, E.; Kõljalg, S.; Truusalu, K.; Stsepetova, J.; Smidt, I.; Kolk, H.; Zagura, M.; Mikelsaar, M. (2012). Safety of probiotic cheese containing Lactobacillus plantarum Tensia according to a variety of health indices in different age groups. Journal of Dairy Science, 95 (10), 5495−5509. DOI: 10.3168/jds.2011-4756.
1.2.
2012
Mikelsaar, Marika; Hütt, Pirje; Stsepetova, Jelena; Smidt, imbi; Shkut, Elena; Rätsep, Merle; Zilmer, Mihkel; Songisepp, Epp (2012). Probiotic Heart cheese "Harmony" comprising L. plantarum Tensia influences blood pressure and metabolic health indices (in Russian). Voprossõ pitanija, 81 (3), 74−81.
5.2.
2012
Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika; Mändar, Reet. (2012). Human Microbiota Biobank (HUMB) at University of Tartu, Estonia. 31st annual meeting of the European Culture Collections' Organization, Braga, Portugal, 14-15 June 2012..
5.2.
2012
Kõljalg, S.; Truusalu, K.; Stsepetova, J.; Pai, K.; Vainumäe, I.; Hütt, P.; Smidt, I.; Mändar, R.; Sepp, E.; Mikelsaar, M. (2012). The role of phylogenetic groups of Escherichia coli in childhood recurrent urinary tract infections. 22nd European Congress ofClinical Microbiology and Infectious Diseases, London, United Kingdom, 31 March – 3 April 2012.
1.1.
2011
Kullisaar, Tiiu; Shepetova, Jelena; Zilmer, Kersti; Songisepp, Epp; Rehema, Aune; Mikelsaar, Marika; Zilmer, Mihkel (2011). An antioxidant probiotic reduces postprandial lipemia and oxidative stress. Central European Journal of Biology, 32−40. DOI: 10.2478/s11535-010-0103-4.
1.1.
2011
Uibo, R.; Panarina, M.; Teesalu, K.; Talja, I.; Sepp, E.; Utt, M.; Mikelsaar, M.; Heilman, K.; Uibo, O.; Vorobjova, T. (2011). Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity? Cellular and Molecular Immunology, 8 (2), 150−156.
1.1.
2011
Stsepetova, Jelena; Sepp, Epp; Kolk, Helgi; Loivukene, Krista; Songisepp, Epp; Mikelsaar, Marika (2011). Diversity and metabolic impact of intestinal Lactobacillus sp. in healthy adults and the elderly. British Journal Of Nutrition, 105 (8), 1235−1244. DOI: 10.1017/S0007114510004770.
1.1.
2011
Mikelsaar, M. (2011). Human microbial ecology: lactobacilli, probiotics, selective decontamination. Anaerobe, 463−467. DOI: 10.1016/j.anaerobe.2011.07.005.
1.2.
2011
Hütt, P.; Stsepetova, J.; Alvarez, B.; Mändar, R.; Krogh-Andersen, K.r; Marcotte, H.; Hammarström, L.; Mikelsaar, M. (2011). Safety and persistence of orally administered human Lactobacillus sp. strains in healthy adults. Beneficial Microbes, 2, 79−90.
1.2.
2011
Mikelsaar, Marika; Lazar, Veronica; Onderdonk, Andrew Bruce ; Donelli, Gianfranco (2011). Do probiotic preparations for humans really have efficacy? Microbial Ecology in Health and Disease, 22, 10128. DOI: 10.3402/mehd.v22i0.10128.
5.2.
2011
Songisepp, Epp; Hütt, Pirje; Rätsep, Merle; Shkut, Elena; Zilmer, Mihkel; Kõljalg, Siiri; Truusalu, Kai; Smidt, Imbi; i Kolk, Helg; Zagura, Maksim; Mikelsaar, Marika (2011). Safety of a probiotic cheese comprising L. plantarum TENSIA according variety of health indices in different age groups. 6th Probiotics Prebiotics New Foods. , 48.
1.1.
2010
Mikelsaar, M.; Stsepetova, J.; Hütt, P.; Kolk, H.; Sepp, E.; Lõivukene, K.; Zilmer, K.; Zilmer, M. (2010). Intestinal Lactobacillus sp. is associated with some cellular and metabolic characteristics of blood in elderly people. Anaerobe, 16 (3), 240−246. DOI: 10.1016/j.anaerobe.2010.03.001.
1.1.
2010
Truusalu, K.; Kullisaar, T.; Hütt, P.; Mahlapuu, R.; Aunapuu, M.; Arend, A.; Zilmer, M.; Mikelsaar, R.; Mikelsaar, M. (2010). Immunological, antioxidative, and morphological response in combined treatment of ofloxacin and Lactobacillus fermentum ME-3 probiotic in Salmonella Typhimurium murine model. Apmis, Nov; 118 (11), 864−72.
1.1.
2010
Kõll, Piret; Mändar, Reet; Smidt, Imbi; Hütt, Pirje; Truusalu, Kai; Mikelsaar, Raik-Hiio; Shchepetova, Jelena; Krogh-Andersen, Kasper; Marcotte, Harold; Hammarström, Lennar; Mikelsaar, Marika. (2010). Screening and evaluation of human intestinal lactobacilli for the development of novel gastrointestinal probiotics. Current Microbiology, 61 (6), 560−566. DOI: 10.1007/s00284-010-9653-y.
1.1.
2010
Prangli, AL; Utt, M; Talja, I; Sepp, E; Mikelsaar, M; Rajasalu, T; Uibo, O; Tillmann, V; Uibo, R. (2010). Antigenic proteins of Lactobacillus acidophilus that are recognised by serum IgG antibodies in children with type 1 diabetes and coeliac disease. Pediatric Allergy and Immunology, 21 (4), e772−e779. DOI: 10.1111/j.1399-3038.2009.00904.x.
1.1.
2010
Kullisaar, T.; Songisepp, E.; Aunapuu, M.; Kilk, K.; Arend, A.; Mikelsaar, M.; Rehema, A.; Zilmer, M. (2010). Complete Glutathione System in Probiotic L. fermentum ME-3. Applied Biochemistry and Microbiology, 46 (5), 481−486. DOI: 10.1134/S0003683810050030.
5.2.
2010
Naaber, P.; Truusalu, K.; Smidt, I.; Kõljalg, S.; Sepp, E.; Hütt, P.; Mändar, R.; Mikelsaar, M. (2010). Protective effect of xylitol and lactobacilli against Clostridium difficile infection in hamster model. Clinical Microbiology and Infection, 16 : 20th ECCMID, Vienna, Austria 10-13 April 2010. (2).
1.1.
2009
Sepp, E.; Stsepetova, J.; Lõivukene, K.; Truusalu, K.; Kõljalg, S.; Naaber, P.; Mikelsaar, M. (2009). The occurrence of antimicrobial resistance and class 1 integrons among commensal Escherichia coli isolates from infants and elderly persons. Annals of Clinical Microbiology and Antimicrobials, 8 (34), 1−6.
1.1.
2009
Hütt, P.; Andreson, H.; Kullisaar, T.; Vihalemm, T.; Unt, E.; Kals, J.; Kampus, P.; Zilmer, M.; Mikelsaar, M. (2009). Effects of a synbiotic product on blood antioxidative activity in subjects colonized with Helicobacter pylori. Letters in Applied Microbiology, 48 (6), 797−800. DOI: 10.1111/j.1472-765X.2009.02607.x.
1.1.
2009
Kõljalg, S.; Truusalu, K.; Vainumäe, I.; Štšepetova, J.; Sepp, E.; Mikelsaar, M. (2009). Persistence of Escherichia coli clones and phenotypic and genotypic antibiotic resistance in recurrent tract infections in childhood. Journal of Clinical Microbiology, 47 (1), 99−105. DOI: 10.1128/JCM.01419-08.
1.2.
2009
Mikelsaar, M.; Zilmer, M. (2009). Lactobacillus fermentum ME-3 - an antimicrobial and antioxidative probiotic. Microbial Ecology in Health and Disease, 21 (1), 1−27. DOI: 10.1080/08910600902815561.
3.2.
2009
Hütt, P.; Songisepp, E.; Rätsep , M.; Shkut, E.; Mikelsaar, M. (2009). L. plantarum TENSIA comprising probiotic cheese with hypotensive effect. Cibus. Ciornale Dell’alimentazione e patologie correlate, 5. Itaalia, Rooma: University Press S.r.l. Roma, 43.
3.4.
2009
Songisepp, E.; Zilmer, M.; Hütt, P., Rätsep, M.; Utt, M.; Üksti, J.; Kõljalg, S.; Zilmer, K.; Mikelsaar, M. (2009). Lactobacillus plantarum TENSIA™ (DSM 21380) as a novel probiotic. Гастроэнтерология Санкт-Петербурга, 4. , A25.
3.5.
2009
Štšepetova, J.; Sepp, E.; Kolk, H.; Lõivukene, K.; Hütt, P.; Songisepp, E.; Mikelsaar, M. (2009). Soole laktobatsillid tervetel täiskasvanutel ja eakatel isikutel. Eest Arst, 9. , 604−605.
5.2.
2009
Hütt, P.; Alvarez, B.; Stsepetova, J.; Truusalu, K.; Mändar, R.; Kõll, P.; Marcotte, H.; Krogh-Andersen, K.; Mikelsaar, M. (2009). Safety and persistence of orally administered human Lactobacillis sp. starins in health adults. Гастроэнтерология Санкт-Петербурга, 4, A11−A11.
5.2.
2009
Štšepetova, J.; Kullisaar, T.; Songisepp, E.; Zilmer, M.; Mikelsaar, M. (2009). Design of L. fermentum ME-3 strain-specific primersfor detecting the cell number in human feces by real-time PCR. Гастроэнтерология Санкт-Петербурга, 4, A26−A27.
5.2.
2009
Sepp, E.; Lõivukene, K.; Julge, K.; Voor, T.; Mikelsaar, M. (2009). How gut microbiotais is associated to children overweight. Gastroenterologiia Sankt-Peterburga, 4: XXXII Inernational Congress of the Society for Microbial Ecology and Disease; Sankt Peterburg, Russia; 29.-30.10.2009. , A23.
5.2.
2009
Jaanimäe, L.; Sepp, E.; Štšepetova, J.; Kõljalg, S.; Mikelsaar, M. (2009). Eesti nosokomiaalse Clostridium difficile tundlikkus antibiootikumidele. Eesti Arst, 9. , 583.
6.7.
2009
Mikelsaar, M.; Songisepp, E.; Smidt, I.; Stsepetova J., Hütt, P.; Zilmer, M.; Truusalu, K.; Kilk, K. (2009). PCT/EE2009/000006 "Isolated Lactobacillus plantarum strain Inducia DSM 21379 as probiotic that enhances natural immunity and food products and medicinal preparations comprising it". Espacenet, x−x.
6.7.
2009
Songisepp, E.; Mikelsaar, M.; Rätsep, M.; Zilmer, M.; Zilmer , K.; Üksti, J.; Kõljalg, S. (2009). Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Tensia DSM 21380 kui antimikroobne ja antihüpertensiivne probiotik, toiduprodukt ja Komposition mis sisaldab vastavat mikroorganismi ja selle mikroorganismi kasutus antihüpertensiivse ravimi valmistamiseks ja meetod patogeenide ja mitte-starter laktobatsillide allasurumiseks toiduproduktis. Espacenet, x−x.
1.1.
2008
Truusalu, K.; Mikelsaar, R-H.; Naaber, P.; Karki, T.; Kullisaar, T.; Zilmer, M.; Mikelsaar, M. (2008). Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin. BMC Microbiology, 8 (132), 1−6. DOI: 10.1186/1471-2180-8-132.
1.1.
2008
Kaur, S.; Kullisaar, T.; Mikelsaar, M.; Eisen, M.; Rehema, A.; Vihalemm, T.; Zilmer, K.; Zilmer, M. (2008). Successful management of mild atopic dermatitis in adults with probiotics and emollients. Central European Journal of Medicine, 3, 215−220.
1.1.
2008
Kõll, P.; Mändar, R.; Marcotte, H.; Leibur, E.; Mikelsaar, M.; Hammarström, L. (2008). Characterization of oral lactobacilli as potential probiotics for oral health. Oral Microbiology and Immunology, 23 (2), 139−147. DOI: 10.1111/j.1399-302X.2007.00402.x.
1.2.
2008
Mikelsaar, M.; Hütt, P.; Kullisaar, T.; Zilmer, K.; Zilmer, M. (2008). Double benefit claims for antimicrobial and antioxidative probiotic. Microbial Ecology in Health and Disease, 20 (4), 184−188. DOI: 10.1080/08910600802408178.
3.4.
2008
Kullisaar, T.; Mikelsaar, M.; Kaur, S.; Songisepp, E.; Zilmer, K.; Hütt, P.; Lukmann, A.; Maaroos, J.; Kals, J.; Zilmer, M. (2008). Probiotics, oxidative stress, inflammation and diseases. Proceedings of the 2008 Joint Central European Congress, 4th Central European Congress on Food 6th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists, 1: The 2008 Joint Central European Congress, 4th Central European Congress on Food 6th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists; Croatia; 15-17 May 2008. Central European Science JournalS, 367−373.
3.5.
2008
Stsepetova J, Sepp E, Julge K, Mikelsaar M. (2008). Intestinal microbiota in non-allergic ja allergic 5-year-old Estonian children. 2nd Baltic Allergy Congress, Programme and abstract book: 2nd Baltic Allergy Congress, Tallinn, 23.-24. mai 2008. Tallinn, 78.
5.1.
2008
Hütt, P; Unt, E; Stsepetova, J; Smidt, I; Kullisaar, T; Zilmer, M; Mikelsaar, M. (2008). H-pylori colonization is associated with general oxidative stress-related and inflammatory markers. Absract Book of 21st International Worksop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer, 5: 21st International Worksop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer, 18-20.09.2008, Riga. HELICOBACTER , 395−395. (13).
5.2.
2008
K. Truusalu, RH. Mikelsaar, T. Kullisaar, M. Aunapuu, A. Arend, M. Zilmer, M. Mikelsaar (2008). Factors involved in combined treatment with probiotic and fluorokinolone in Salmonella Typhimurium murine infection. 18 ECCMID, Barcelona 20-24.04.08. Hispaania.
5.2.
2008
Truusalu, K.; Kõljalg, S.; Stsepetova, J.; Drell, T.; Vainumäe, I.; Sepp, E.; Mikelsaar, M. (2008). Persistence of Escherichia coli clones and resistance genes in recurrent urinary tract infections in children. 18th ECCMID; Barcelona; 20-24.04.2008. Hispaania, Barcelona.
5.2.
2008
Songisepp, E.; Mikelsaar, M.; Zilmer, M.; Hütt, P.; Smidt, I.; Stsepetova, J.; Truusalu, K.; Rätsep, M.; Kilk, K.; Utt, M.; Üksti, J.; Kõljalg, S., Zilmer, K. (2008). Lactobacillus plantarum TENSIA (DSM 21380) and L. plantarum INDUCIA (DSM 21379) as novel probiotics. FIL-IDF World Dairy Summit, Mecixo City, Mexico, 11-14 November 2008. Mexico City.
5.2.
2008
Stsepetova, J.; Kõljalg, S.; Sepp, E.; Lõivukene, K.; Songisepp, E.; Rätsep, M.; Mikelsaar, M. (2008). Antibiotic susceptibility pattern and tetracycline resistance of Lactobacillus strains of different origin. Clinical Microbiology and Infection, 14: 18th European Congress of Clinical Microbiology and Infectious Diseases. , Abstract number: P1210. (S7).
6.7.
2008
Mikelsaar, M.; Songisepp, E.; Smidt, I.; Stsepetova, J.; l Zilmer, M.; Hütt, P.; Truusalu, K.; Kilk, K. (2008). Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Inducia DSM 21379 kui organismi loomulikku kaitsevõimet tõstev probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine rakulist immuunsust tõstva ravimi valmistamiseks.
1.1.
2007
Štšepetova, J.; Sepp, E.; Julge, K.; Vaughan, E.; Mikelsaar, M.; de Vos, W.M. (2007). Molecularly assessed shifts of Bifidobacterium ssp. and less diverse microbial communities are characteristic of 5-year-old allergic children. FEMS Immunology & Medical Microbiology, 51 (2), 260−269.
1.1.
2007
Andreson, H.; Sillakivi, T.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2007). Persistence of Helicobacter pylori infection in patients with peptic ulcer perforation. Scandinavian Journal of Gastroenterology, 42 (3), 324−329. DOI: 10.1080/00365520600930859.
3.4.
2007
Hütt, Pirje; Songisepp, Epp; Mikelsaar, Marika (2007). Antagonistic Activity of Lactobacillus plantarum Strains Against Enteropathogens. VTT Symposium, 248: The 1st SAFOODNET seminar ‘Microbial contaminants & Contamination routes in food industry’ Food safety and hygiene networking FP6-022808-2006. Espoo, VTT, January 22-23, 2007. Ed. Wirtanen, G.; Salo, S. VTT (Valtion Teknillinen Tutkimuskesk) TECHNICAL RESEARCH CENTRE, 72−73.
3.4.
2007
Mikelsaar, M. (2007). Enteric pathogens- prevalence in food products and mechanisms of suppression by probiotic lactic acid bacteria. In: Wirtanen, G.; Salo, S. (Ed.). Food safety and hygiene networking FP6-022808-2006. SAFOODNET (31−35). . Helsinki: Finnish Academy Tech Sci. (Technical research centre of Finland (VTT) symposium; 248).
3.4.
2007
Mikelsaar, M. (2007). Impact of composition and metabolites of intestinal microbiota on foodborne infections. In: Wirtanen, G.; Salo, S. (Ed.). Food safety and hygiene networking FP6-022808-2006. SAFOODNET. Technical research centre of Finland (VTT) symposium 248, ed. G. Wirtanen, S. Salo, 2007, Helsinki (24−27). . Espoo, Helsinki: Finnish Academy Tech Sci. (VTT Symposium; 248).
3.5.
2007
Songisepp, E.; Rätsep, M.; Üksti, J.; Zilmer, K.; Hütt, P.; Mikelsaar, M. (2007). The improvement of cheese quality with human Lactobacillus plantarum additive. 1st open seminary arranged by SAFOODNET “Microbial Contaminants and contamination routes in food industry”; Espoo; Finland; January 22-23, 2007.
3.5.
2007
Mikelsaar, M. (2007). The evidence for microbiological role as triggers of exacerbations and modifiers of the natural history of asthma. In: ERS School Postgraduate Course PG24-GRACE full-day course. From cough to asthma: the role of infection (33−49). . European Respiratory society (ESCMID).
3.5.
2007
Kullisaar, T.; Zilmer, K.; Mikelsaar, M.; Songisepp, E.; Zilmer, M. (2007). Consumption of antioxidative probiotic L. fermentum ME-3 enriched kefir has beneficial impact on both postprandial profile and postprandial oxidative stress. Kliiniline toitumine (vene keeles), 1-2: International Congress on Probiotics, Prebiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects; St. Petersburg, Russia; May 15-16, 2007. Peterburg: Medlain-Medina, A6.
5.1.
2007
Saulnier, D.M.A.; Hutt, P.; Mikelsaar, M., Bosscher, D.; Gibson, G.; Kolida, S. (2007). Effects of a synbiotic on biomarkers of oxidative stress and faecal microbiota in healthy adults: results of a cross-over double-blind placebo-controlled trial. Proceedings of the Nutrition Society, 66. , 101A.
5.2.
2007
Stsepetova, J.; Sepp, E.; Lõivukene, K.; Kolk, H.; Mikelsaar, M. (2007). Individual diversity of intestinal lactobatsilli in healthy elderly. Kliiniline toitumine (vene keeles), 1-2: Probiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects; St. Petersburg, Russia; May 15-16. Peterburg: Medlain-Medina, A15.
5.2.
2007
Smidt, I.; Stsepetova, J.; Hütt, P.; Sepp, E.; Mikelsaar, M. (2007). Evaluation of biogenic amines in urine after synbiotic consumption. Klinitseskoje pitanije, 1-2: Probiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects, May 15-16, 2007 Peterburg, Russia. Peterburg: Medlain-Medina, A13−A14.
5.2.
2007
Mikelsaar, R.-H.; Truusalu, K.; Mikelsaar, M. (2007). Probiootilise laktobatsilli ja ofloksatsiini sünergeetiline efekt hiire tüüfuse mudelis. 9. Eesti Arst, 695.
5.2.
2007
Truusalu, K.; Mikelsaar, R.-H.; Naaber, P.; Karki, T.; Kullisaar, T.; Zilmer, M.; Mikelsaar, M. (2007). Probiotic Lactobacillus Fermentum ME-3 ehances ofloxacin effect on Salmonelle Typhimurium infection in a murine model. Kliiniline toitumine (vene keeles), 1-2: Probiotics, Synbiotics and Functional Foods; Scientific and Clinical Aspects; May 15-16. St. Peterburg: Medlain-Medina, A16.
5.2.
2007
Hütt, P.; Songisepp, E.; Guidas, M.; Tamme, T.; Ormanci, Fatma, Seda; Ayaz, N. D.; Korel, F.; Aarnisalo, K.; Hradecká, H.; Mikelsaar, M. (2007). Antimicrobial effects in food and prevention of contamination in food industry. VTT Symposium, 248: The 1st SAFOODNET seminar ‘Microbial contaminants & Contamination routes in food industry’ Food safety and hygiene networking FP6-022808-2006. Espoo,Finland January 22-23 2007. Ed. Wirtanen, G.; Salo, S. VTT Technical Research Centre of Finland, 159−170.
6.2.
2007
Lutsar, I.; Mikelsaar, M.; Karki, T. (2007). Meditsiiniline mikrobioloogia II. Tartu: Tartu Ülikooli Kirjastus.
1.1.
2006
Hütt, P.; Shchepetova, J.; Lõivukene, K.; Kullisaar, T.; Mikelsaar, M. (2006). Antagonistic activity of probiotic lactobacilli and bifidobacteria against entero- and uropathogens. Journal of Applied Microbiology, 100 (6), 1324−1332.
1.1.
2006
Marcotte, H.; Koll-Klais, P.; Hultberg, A.; Zhao, Y.; Mikelsaar, M.; Hammarstrom, L. (2006). Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus. Journal of Applied Microbiology, 100 (2), 256−263.
3.1.
2006
Sepp, E.; Voor, T.; Julge, K.; Lõivukene, K.; Björksten, B.; Mikelsaar, M. (2006). Ia intestinal microbiota bound up with changing lifestyle? In: A. Mendez-Vilas (Ed.). Modern Multidisciplinary Applied Microbiology: Exploiting Microbes and Their Interactions (708−712). . Germany: Wiley.
5.2.
2006
Štšepetova, J.; Sepp, E.; Truusalu, K.; Lõivukene, K.; Hütt, P.; Songisepp, E.; Mikelsaar, M. (2006). The prevalence of mobile gene cassettes in indigenous gut microbiota and dairy starter bacteria. Reproduction Nutrition Development, 46: Gut Microbiolology - Research to Improve Health, Immune Response and Nutrition, Aberdeen, Scotland, UK; 21-23 June, 2006. , S31.
5.2.
2006
Hütt, P.; Songisepp, E.; Mikelsaar, M. (2006). Antagonistic activity of putative probiotic Lactobacillus strains against enteropathogens. 13th World Congress of Food Science and Technology "Food is Life"; Nantes, France; 17-21 September, 2006.
5.2.
2006
Hütt, P.; Stsepetova, J.; Kullisaar, T.; Kals, J.; Zilmer, M.; Mikelsaar, M. (2006). Positive effect of synbiotic consumption in healthy volunteers. 3rd Central European Congress on Food; Sofia, Bulgaria; 22-24 May, 2006.
5.2.
2006
Štšepetova, Jelena; Sepp, Epp; Truusalu, Kai; Lõivukene, Krista; Hütt, Pirje; Songisepp, Epp; Mikelsaar, Marika (2006). Esimese klassi integronide esinemine indigeense E. coli ja toiduainetetööstuses kasutatavatel piimhapet produtseerivatel bakteritel. Eesti Arst, 9, 635.
5.2.
2006
Kõll, P.; Mändar, R.; Marcotte, H.; Leibur, E.; Mikelsaar, M.; Hammarström, L. (2006). Characterization of oral lactobacilli as potential probiotics. IADR-PEF. , 94.
5.2.
2006
Kõll, P.; Mändar, R.; Smidt, I.; Mikelsaar, M. (2006). Characterization of intestinal lactobacilli as potential second-generation probiotics. ECCMID. , 76.
5.2.
2006
Prangli, A.-L.; Utt, M.; Sepp, E.; Mikelsaar, M.; Uibo, O.; Tillmann, V.; Oona, M.; Rajasalu, T.; Talja, I.; Uibo, R. (2006). Laktobatsillivastaste antikehade määramine seerumis immunoblotmeetodiga. Eesti Arst, 85 (9), 643.
5.2.
2006
Truusalu, K.; Sepp, E.; Shchepetova, L.; Naaber, P.; Stroo, K.; Sepp, K.; Mikelsaar, M. (2006). Prevalence of class 1 integrons and MIC values in indigenous and pathogenic E. coli strains in different age groups. 16th European Congress of Clinical Microbiology and Infectious Diseases: ESCMID; Nice, France; 1-4 April, 2006. , P939.
6.2.
2006
Mikelsaar, M.; Karki, T.; Lutsar, I.; Mändar, R. (2006). Meditsiiniline mikrobioloogia I. Tartu: Tartu Ülikooli Kirjastus.
6.2.
2006
Mikelsaar, M.; Karki, T.; Lutsar, I.; Mändar, R. (2006). Meditsiiniline mikrobioloogia I osa. Tartu: Tartu Ülikooli Kirjastus.
1.1.
2005
Koll-Klais, P.; Mandar, R.; Leibur, E.; Marcotte, H.; Hammarstrom, L.; Mikelsaar, M. (2005). Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiology and Immunology, 20 (6), 354−361.
1.1.
2005
Sepp, E.; Julge, K.; Mikelsaar, M.; Bjorksten, B. (2005). Intestinal microbiota and immunoglobulin E responses in 5-year-old Estonian children. Clinical & Experimental Allergy, 35 (9), 1141−1146.
1.2.
2005
Songisepp, E.; Kals, J.; Kullisaar, T.; Mändar, R.; Hütt, P.; Zilmer, M.; Mikelsaar, M. (2005). Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutrition Journal, 4 (22), 141−146.
1.2.
2005
Kasenõmm, P.; Piirsoo, A.; Kull, M.; Kull, M. Jr.; Mikelsaar, M. (2005). Selection of indicators for tonsillectomy in adults with recurrent tonsillitis. BMC Ear, Nose and Throat Disorders, 5:7, 1−8. DOI: 10.1186/1472-6815-5-7.
1.2.
2005
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Mikelsaar, M. (2005). Oral microbial ecology in chronic periodontitis and periodontal health. Microbial Ecology in Health and Disease, 17 (3), 146−155.
1.3.
2005
Kasenõmm, P.; Piirsoo, A.; Kull, M; Kull, M.; Mikelsaar, M. (2005). Kroonilise tonsilliidi patogeneesi uuringud kui alus tonsillektoomia objektiivsete kriteeriumite leidmiseks. Eesti Arst, 84 (8), 531−541.
3.4.
2005
Hütt, P.; Shchepetova, J.; Lõivukene, K.; Mikelsaar, M. (2005). Determination of antagonistic activities of different probiotics against pathogens. 8th symposium on Lactic Acid Bacteria; Egmond aan Zee, The Netherlands; 28 August - 01 September, 2005.
5.1.
2005
Andreson, H.; Sillakivi, T.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2005). In perforated peptic ulcer patients Helicobacter pylori infection tends to persist. Helicobacter, 10 (5), 481−481.
5.2.
2005
Zilmer, M.; Songisepp, E.; Kullisaar, T.; Zilmer, K.; Mikelsaar, M. (2005). Lactobacillus fermentum: probiotic and health characteristics essential for conception of functional food. 18th International Congress of Nutrition; Durban, South Africa; 19.-23.09.2005.
5.2.
2005
Mikelsaar, M.; Truusalu, K.; Kullisaar, T.; Naaber, P.; Mikelsaar, R.-H.; Zilmer, M. (2005). Effect of probiotic induced antioxidative response in experimental murine typhoid. XI International Congress of Bacteriology and Applied Microbiology; California, USA; July 2005.
5.2.
2005
Kullisaar, T.; Lukman, A.; Zilmer, K.; Vihalemm, T.; Mikelsaar, M.; Zilmer, M. (2005). Probiotic L. fermentum ME-3 may have impact on the rehabilitation quality of elderly stroke patients. 18th International Congress of Nutrition; Durban, South Africa; September 19-23, 2005. , 301.
5.2.
2005
Songisepp, E.; Kals, J.; Hütt, P.; Mändar, R.; Mikelsaar, M. (2005). Impact of the probiotic L. fermentum ME-3 consumption with different formulations and daily doses on the fecal lactoflora, its composition and ME-3 fecal recovery. 8th Symposium on Lactic Acid Bacteria. Book of Abstract: 8th Symposium on Lactic Acid Bacteria; Egmond aan Zee, The Netherlands; 28 August-01 September, 2005.
5.2.
2005
Shehpetova, J.; Truusalu, K.; Sepp, E.; Mikelsaar, M. (2005). Sulfamethoxazole resistance gene in uropathogenic E. coli. 15th European Congress of Clinical Microbiology and Infectious Diseases: ESCMID; Copenhagen, Denmark; 2-5 April 2005. , 404.
5.2.
2005
Hütt, Pirje; Štšepetova, Jelena; Lõivukene, Krista; Mikelsaar, Marika (2005). Probiootikumide antagonistliku aktiivsuse erinevus sõltuvalt kasvukeskkonnast. Eesti Arst, 9, 656−657.
5.2.
2005
Kõll-Klais, P.; Mändar, R.; Smidt, I.; Mikelsaar, M. (2005). Laktobatsillide valik kasutamiseks teise põlvkonna probiootikumidena. Eesti Arst, 9. , 665.
5.2.
2005
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Marcotte, H.; Hammarström, L.; Mikelsaar, M. (2005). Oral lactobacilli in chronic periodontitis: species composition and antimicrobial activity. IADR. , 31.
1.1.
2004
Naaber, P.; Mikelsaar, M. (2004). Interactions between lactobacilli and antibiotic-associated diarrhea. Advances in Applied Microbiology, 54, 231−260.
1.1.
2004
Naaber, P.; Smidt, I.; Stsepetova, J.; Brilene, T.; Annuk, H.; Mikelsaar, M. (2004). Inhibition of Clostridium difficile strains by intestinal Lactobacillus species. Journal of Medical Microbiology, 53 (6), 551−554.
1.1.
2004
Songisepp, E.; Kullisaar, T.; Hutt, P.; Elias, P.; Brilene, T.; Zilmer, M.; Mikelsaar, M. (2004). A new probiotic cheese with antioxidative and antimicrobial activity. Journal of Dairy Science, 87 (7), 2017−2023.
1.1.
2004
Kasenomm, P.; Mesila, I.; Piirsoo, A.; Kull, M.; Mikelsaar, M.; Mikelsaar, RH. (2004). Macroscopic oropharyngeal signs indicating impaired defensive function of palatine tonsils in adults suffering from recurrent tonsillitis. Apmis, 112, 248−256.
1.1.
2004
Maaroos, H.-I.; Andreson, H.; Loivukene, K.; Hutt, P.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2004). The diagnostic value of endoscopy and Helicobacter pylori tests for peptic ulcer patients in late post-treatment setting. BMC Gastroenterology, 4, Art.No. 27.
1.2.
2004
Truusalu, K.; Naaber, P.; Kullisaar, T.; Tamm, H.; Mikelsaar, R.; Zilmer, K.; Rehema, A.; Zilmer, M.; Mikelsaar, M. (2004). The influence of antibacterial and antioxidative probiotic lactobacilli on gut mucosa in a mouse model of Salmonella infection. Microbial Ecology in Health and Disease, 16 (4), 180−187. DOI: 10.1080/08910600410021783.
3.1.
2004
Mikelsaar, M.; Mändar, R.; Sepp, E.; Annuk, H. (2004). Human lactic acid microflora and its role in the welfare of the host. In: Salminen, S.; von Wright, A. (Ed.). Lactic Acid Bacteria (453−506). . New York: Marcel Dekker Inc. (Food science and technology; 139).
5.2.
2004
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2004). Subgingival microbial relations in chronic periodontitis and periodontal health. Microbial Ecology in Health and Disease: SOMED; Helsingör, Denmark; 6-9 May, 2004. Taylor & Francis Ltd.
5.2.
2004
Mikelsaar, R.; Truusalu, K.; Murde, M.; Naaber, P.; Mikelsaar, M. (2004). Probiotic lactobacilli enhance eradication of Salmonella Typhimurium in animal model. Abstr. 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004, Washington D.C.: 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004, Washington D.C.. Amer Soc Microbiology, 61.
5.2.
2004
Mikelsaar, M. (2004). Probiotic lactobacilli vs. Helicobacter pylori. Microbial ecology in health and disease: SOMED, Helsingör, Taani, 6.-9. Mai 2004. , 23.
5.2.
2004
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Mikelsaar, M. (2004). Suuõõne laktobatsillide antagonistlikud omadused parodontiiti põhjustavate patogeenide suhtes. Eesti Arst, 9. , 615.
1.1.
2003
Annuk, H.; Shchepetova, J.; Kullisaar, T.; Songisepp, E.; Zilmer, M.; Mikelsaar, M. (2003). Characterization of intestinal lactobacilli as putative probiotic candidates. Journal of Applied Microbiology, 94 (3), 403−412.
1.1.
2003
Kullisaar, T.; Songisepp, E.; Mikelsaar, M.; Zilmer, K.; Vihalemm, T.; Zilmer, M. (2003). Antioxidative probiotic fermented goats' milk decreases oxidative stress-mediated atherogenicity in human subjects. British Journal Of Nutrition, 90 (2), 449−456.
1.2.
2003
Maaroos, H-I.; Andreson, H.; Lõivukene, K.; Hütt, P.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2003). The diagnostic value of endoscopy and H. pylori tests for peptic ulcer patients in late post-treatment setting. BMC Gastroenterology, 4 (27), 1−6. DOI: 10.1186/1471-230X-4-27.
1.2.
2003
Lõivukene, K.; Kolk, H.; Rägo, T.; Oona, M.; Maaroos, H-I.; Mikelsaar, M. (2003). The gastric ecology of H. pylori positive and negative Children and adults. Microecology and Therapy, 29, 71−78.
1.3.
2003
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2003). Suuõõne mikroobiökoloogia kroonilise parodontiidi puhul. Eesti Arst, 82 (11), 759−767.
1.3.
2003
Sepp, E.; Kõljalg, S.; Truusalu, K.; Štšepetova, L.; Metsvaht, T.; Sau, L.; Jürna, M.; Mägi, H.; Allik, M.; Mikelsaaar, M. (2003). Staphylococcus epidermidis ja Klebsiella pneumoniae - võimalikud hospitaalinfektsioonide tekitajad Eesti lasteintensiivravi osakondades. Eesti Arst, 82 (4), 239−248.
5.1.
2003
Andreson, H.; Maaroos, H.-I.; Mikelsaar, M. (2003). Reliability of noninvasive Helicobacter pylori antigen stool test ImmunoCard STAT! HpSA in peptic ulcer patients after eradicative treatment. Abstracts of the XVIth International Workshop on Gastrointestinal Pathology and Helicobacter. European Helicobacter Study Sroup. Stockholm, September 3-6, 2003: XVIth International Workshop on Gastrointestinal Pathology and Helicobacter. European Helicobacter Study Sroup; Stockholm, Sweden; 3-6 September, 2003. Ed. D.G. Graham. Blackwell Publishing, 490−490. (Helicobacter; 8(4)).
5.2.
2003
Lõivukene, K.; Maaroos, H.; Mikelsaar, M. (2003). Antimicrobial potential of lactobacilli against reference and wild Helicobacter pylori strains. Clinical Microbiology and Infection, S1, 143.
5.2.
2003
Hütt, P.; Songisepp, E.; Kullisaar, T.; Mikelsaar, M.; Zilmer, M. (2003). L. fermentum ME-3 tervist parandava toime uurimine. Eesti Arst, 9, 623.
5.2.
2003
Truusalu, Kai; Sepp, Epp; Naaber, Paul; Murde, Maret; Mikelsaar, Raik-Hiio; Mikelsaar, Marika (2003). Escherichia coli infektsiooni hematogeenne disseminatsioon. Eesti Arst, 9, 659.
1.1.
2002
Koljalg, S.; Naaber, P.; Mikelsaar, M. (2002). Antibiotic resistance as an indicator of bacterial chlorhexidine susceptibility. Journal of Hospital Infection, 51 (2), 106−113.
1.1.
2002
Kruuner, A.; Pehme, L.; Ghebremichael, S.; Koivula, T.; Hoffner, SE.; Mikelsaar, M. (2002). Use of molecular techniques to distinguish between treatment failure and exogenous reinfection with Mycobacterium tuberculosis. Clinical Infectious Diseases, 35 (2), 146−155.
1.1.
2002
Kullisaar, T.; Zilmer, M.; Mikelsaar, M.; Vihalemm, T.; Annuk, H.; Kairane, C.; Kilk, A. (2002). Two antioxidative lactobacilli strains as promising probiotics. International Journal of Food Microbiology, 72 (3), 215−224.
1.1.
2002
Hynes, SO.; Broutet, N.; Wadstrom, T.; Mikelsaar, M.; O'Toole, PW.; Telford, J.; Engstrand, L.; Kamiya, S.; Mentis, AF.; Moran, AP. (2002). Phenotypic variation of Helicobacter pylori isolates from geographically distinct regions detected by lectin typing. Journal of Clinical Microbiology, 40 (1), 227−232.
1.1.
2002
Andreson, H.; Loivukene, K.; Sillakivi, T.; Maaroos, HI.; Ustav, M.; Peetsalu, A.; Mikelsaar, M. (2002). Association of cagA and vacA genotypes of Helicobacter pylori with gastric diseases in Estonia. Journal of Clinical Microbiology, 40 (1), 298−300.
1.1.
2002
Loivukene, K.; Maaroos, HI.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2002). Prevalence of antibiotic resistance of Helicobacter pylori isolates in Estonia during 1995-2000 in comparison to the consumption of antibiotics used in treatment regimens. Clinical Microbiology and Infection, 8 (9), 598−603.
1.1.
2002
Kolk, H.; Maaroos, H-I.; Kull, I.; Labotkin, K.; Lõivukene, K.; Mikelsaar, M. (2002). Open access endoscopy in an epidemiological situation of high prevalence of Helicobacter pylori infection: applicability of the guidelines of the European Society for Primary Care Gastroenterology. Family Practice, 19 (3), 231−235.
1.2.
2002
Kasenõmm, P.; Kull, M.; Mikelsaar, M. (2002). Association between tonsillar core microflora and post-tonsillectomy bacteremia. Microbial Ecology in Health and Disease, 14 (2), 122−127.
1.2.
2002
Stsepetova, E; Sepp, E; Hütt, P; Mikelsaar, M. (2002). Estimation of lactobacill, enterococci and bifidobacteria in fecal samples by quantitative bacteriology and FISH. Microecology and Therapy, 29, 51−59.
1.2.
2002
Mikelsaar, M.; Annuk, H.; Shchepetova, J.; Mändar, R.; Sepp, E.; Björksten, B. (2002). Intestinal lactobacilli of Estonian and Swedish children. Microbial Ecology in Health and Disease, 14, 75−80.
1.2.
2002
Lõivukene, K.; Kolk, H.; Rägo, T.; Oona, M.; Maaroos, H.-I.; Mikelsaar, M. (2002). The gastric ecology of Helicobacter pylori positive and negative children and adults. Microecology and Therapy, 29, 71−78.
5.1.
2002
Andreson, H.; Sillakivi, T.; Peetsalu, A.; Mikelsaar, M. (2002). The dynamics of Helicobacter pylori infection in patients with perforated peptic ulcer. Gut, 51, A18−A18.
5.1.
2002
Koll-Klais, P.; Mandar, R.; Mikelsaar, M.; Leibur, E. (2002). Periodontal microecology in chronic periodontitis patients in an Estonian population. Journal of Dental Research, 81, A206−A206.
5.1.
2002
Kullisaar, T.; Songisepp, E.; Mikelsaar, M.; Zilmer, K.; Vihalemm, T.; Zilmer, M. (2002). Antioxidative and antiatherogenic probiotic lactobacillus ME3. Free Radical Biology and Medicine, 33, S272−S272.
5.2.
2002
Naaber, P.; Tamm, H.; Kullisaar, T.; Zilmer, K.; Rehema, A.; Mikelsaar, R.; Zilmer, M.; Mikelsaar, M. (2002). Laktobatsillide toime salmonelloosi-hiire mudelis. Eesti Arst, 9, 573.
5.2.
2002
Kullisaar, T.; Zilmer, K.; Kaur, S.; Eisen, M.; Rehema, A.; Songisepp, E.; Mikelsaar, M.; Zilmer, M. (2002). Goat milk fermented with antioxidative L.fermentum ME-3 decreases oxidative stress in atopic dermatitis. In: (36−37). 2nd International Symposium on Antioxidants in Nutrition & Therapy: Mechanisms in Physiology-Pathology-Pharmacology; Bali, Indonesia; 2-4 October 2002; abstract book.
5.2.
2002
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2002). Igemetasku mikroobiökoloogia kroonilise parodontiidiga haigetel Eestis. Eesti Arst, 9. , 569.
5.2.
2002
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2002). Microecological relations in periodontal sites of chronic periodontitis (CPD) patients. Anaerobe, 3. , 115. (8).
1.1.
2001
Sillakivi, T.; Aro, H.; Ustav, M.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2001). Diversity of Helicobacter pylori genotypes among Estonian and Russian patients with perforated peptic ulcer, living in Southern Estonia. FEMS Microbiology Letters, 195 (1), 29−33.
1.1.
2001
Mandar, R.; Loivukene, K.; Ehrenberg, A.; Smidt, I.; Raukas, E.; Kask, V.; Mikelsaar, M. (2001). Amniotic fluid microflora in asymptomatic women at mid-gestation. Scandinavian Journal of Infectious Diseases, 33 (1), 60−62.
1.1.
2001
Karki, T.; Truusalu, K.; Vainumae, I.; Mikelsaar, M. (2001). Antibiotic susceptibility patterns of community- and hospital-acquired Staphylococcus aureus and Escherichia coli in Estonia. Scandinavian Journal of Infectious Diseases, 33 (5), 333−338.
1.1.
2001
Mandar, R.; Loivukene, K.; Hutt, P.; Karki, T.; Mikelsaar, M. (2001). Antibacterial susceptibility of intestinal lactobacilli of healthy children. Scandinavian Journal of Infectious Diseases, 33 (5), 344−349.
1.1.
2001
Bjorksten, B.; Sepp, E.; Julge, K.; Voor, T.; Mikelsaar, M. (2001). Allergy development and the intestinal microflora during the first year of life. The Journal of Allergy and Clinical Immunology, 108 (4), 516−520.
1.1.
2001
Annuk, H.; Hynes, SO.; Hirmo, S.; Mikelsaar, M.; Wadstrom, T. (2001). Characterisation and differentiation of lactobacilli by lectin typing. Journal of Medical Microbiology, 50 (12), 1069−1074.
1.1.
2001
Sillakivi, T.; Peetsalu, M.; Mikelsaar, M.; Peetsalu, A. (2001). An attempt at Helicobacter pylori eradication with intravenous clarithromycin in perforated peptic ulcer patients. Scandinavian Journal of Gastroenterology, 36 (10), 1119−1120.
1.2.
2001
Kõljalg, S.; Naaber, P.; Mikelsaar, R.; Mikelsaar, M. (2001). Biocidal effect of protamine and melittin in combination with chlorhexidine. Clinical Microbiology and Infection, 7 (1), 32−34.
1.3.
2001
Sillakivi, T.; Peetsalu, M.; Mikelsaar, M.; Peetsalu, A. (2001). Helicobacter pylori eradikatsioon perforeerunud peptilise haavandiga haigetel. Eesti Arst, 80 (1), 8−11.
5.1.
2001
Mikelsaar, M.; Kullisaar, T.; Zilmer, M. (2001). Antagonistic and antioxidative activity of lactobacilli and survival in oxidative milieu. American Journal of Clinical Nutrition, 73 (2), 495S−495S.
5.2.
2001
Kõll-Klais, P.; Mändar, R.; Naaber, P.; Mikelsaar, M.; Leibur, E. (2001). Parodondi kudede mikroobiökoloogia kroonilise parodontiidiga patsientidel Eestis. Erialane kogumik "Eesti Hambaarstide Päevad 2001": Eesti Hambaarstide Päevad, Tartu, 2001. , 30.
5.2.
2001
Lõivukene, Krista; Aro, Helena; Hütt, Pirje; Kolk, Helgi; Maaroos, Heidi-Ingrid; Mikelsaar, Marika (2001). Erinevate Helicobacter pylori diagnoosivõimaluste efektiivsuse võrdlus. Eesti Arst, 9, 408.
1.1.
2000
Naaber, P.; Smidt, I.; Tamme, K.; Liigant, A.; Tapfer, H.; Mikelsaar, M.; Talvik, R. (2000). Translocation of indigenous microflora in an experimental model of sepsis. Journal of Medical Microbiology, 49 (5), 431−439.
1.1.
2000
Loivukene, K.; Kolk, H.; Maaroos, HI.; Kasenomm, P.; Aro, H.; Ustav, M.; Mikelsaar, M. (2000). Metronidazole and clarithromycin susceptibility and the subtypes of VacA of Helicobacter pylori isolates in Estonia. Scandinavian Journal of Infectious Diseases, 32 (1), 59−62.
1.2.
2000
Tamme, K.; Liigant, A.; Tapfer, H.; Türi, E.; Mikelsaar, M.; Talvik, R. (2000). Multiple organ dissemination of bacteria in experimental sepsis. Papers on Anthropology, 9, 234−240.
1.3.
2000
Lõivukene, K.; Maaroos, H.; Mikelsaar, M.; Kolk, H. (2000). Helicobacter pylori tüvede metronadazool- ja klaritromütsiinitundlikkus Eesti patsientide seas. Eesti Arst, 79 (8), 453−459.
1.3.
2000
Lõivukene, K.; Kolk, H.; Maaroos, H-I.; Mikelsaar, M. (2000). H. pylori tüvede metronidasooli ja klaritromütsiinitundlikkus Eesti patsientide seas. Eesti Arst, 79, 453−459.
3.4.
2000
Karki, Tõnis; Truusalu, Kai; Vainumäe, Inga; Mikelsaar, Marika (2000). Antibiotic resistance of S. aureus and Escherichia coli recovered from inpatients and outpatients in the Estonia. 4th Nordic-Baltic Congress on Infectious Diseases "Prudent use of antibiotics", P−10.
1.1.
1999
Annuk, H.; Hirmo, S.; Turi, E.; Mikelsaar, M.; Arak, E.; Wadstrom, T. (1999). Effect on cell surface hydrophobicity and susceptibility of Helicobacter pylori to medicinal plant extracts. FEMS Microbiology Letters, 172 (1), 41−45.
1.1.
1999
Koljalc, S.; Sults, I.; Raukas, E.; Truu, J.; Ustav, M.; Mikelsaar, M. (1999). Distribution of Acinetobacter baumannii in a neurointensive care unit. Scandinavian Journal of Infectious Diseases, 31 (2), 145−150.
1.1.
1999
Bjorksten, B.; Naaber, P.; Sepp, E.; Mikelsaar, M. (1999). The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clinical & Experimental Allergy, 29 (3), 342−346.
5.1.
1999
Loivukene, K.; Kolk, H.; Mikelsaar, M.; Kasenomm, P.; Ustav, M.; Maaroos, HI. (1999). Comparison of metronidazole susceptibility and vacA subtypes of H-pylori strains in patients with gastritis and peptic ulcer. Gut, 45, A14−A14.
5.2.
1999
Sepp, Epp; Naaber, Paul; Lõivukene, Krista; Kõljalg, Siiri; Voor, Tiia; Björkstén, Bengt; Mikelsaar, Marika (1999). Eesti laste sooletrakti mikrofloora kujunemine esimesel eluaastal. Arstiteaduskonna aastakonverents, 7. oktoober 1999 : teesid, 110−111.
1.1.
1998
Makinen, KK.; Olak, J.; Russak, S.; Saag, M.; Seedre, T.; Vasar, R.; Vihalemm, T.; Mikelsaar, M.; Makinen, PL. (1998). Polyol-combinant saliva stimulants: A 4-month pilot study in young adults. Acta Odontologica Scandinavica, 56 (2), 90−94.
1.1.
1998
Naaber, P.; Mikelsaar, RH.; Salminen, S.; Mikelsaar, M. (1998). Bacterial translocation, intestinal microflora and morphological changes of intestinal mucosa in experimental models of Clostridium difficile infection. Journal of Medical Microbiology, 47 (7), 591−598.
1.2.
1998
Kaila, M.; Isolauri, E.; Sepp, E.; Mikelsaar, M.; Salminen, S. (1998). Fecal recovery of a human Lactobacillus strain (ATCC 53103) during dietary therapy of rotavirus diarrhea in infants. Bioscience and Microflora, 17 (2), 149−151.
1.3.
1998
Mikelsaar, M. (1998). Meditsiinidoktor Andrus-Juhan Voitk. Eesti Arst, 77 (2), 23.
3.1.
1998
Mikelsaar, M.; Mändar, R.; Sepp, E. (1998). Lactic acid microflora in the human microbial ecosystem and its development. In: S. Salminen, A. von Wright (Ed.). Lactic Acid Bacteria: Microbiology and Functional Aspects (Food Science and Technology) (279−342). . New York: Marcel Dekker.
4.2.
1998
Mikelsaar, M.; Mändar, R.(Toim.) (1998). Kliinilise mikrobioloogia käsiraamat. Tallinn: Medicina.
6.2.
1998
Karki, T.; Brilene, T.; Mikelsaar, M. (1998). Praktilised tööd mikrobioloogias I osa. . Tartu: Tartu Ülikooli Kirjastus.
6.2.
1998
Mikelsaar, M.; Karki, T. (1998). Meditsiiniline mikrobioloogia I osa. Tartu: Tartu Ülikooli Kirjastus.
1.1.
1997
Sepp, E.; Julge, K.; Vasar, M.; Naaber, P.; Bjorksten, B.; Mikelsaar, M. (1997). Intestinal microflora of Estonian and Swedish infants. Acta Paediatrica, 86 (9), 956−961.
1.1.
1997
Turi, M.; Turi, E.; Koljalg, S.; Mikelsaar, M. (1997). Influence of aqueous extracts of medicinal plants on surface hydrophobicity of Escherichia coli strains of different origin. Apmis, 105 (12), 956−962.
1.1.
1997
Naaber, P.; Klaus, K.; Sepp, E.; Bjorksten, B.; Mikelsaar, M. (1997). Colonization of infants and hospitalized patients with Clostridium difficile and lactobacilli. Clinical Infectious Diseases, 25, S189−S190.
1.1.
1997
Naaber, P.; Maimets, M.; Mikelsaar, M. (1997). Prevalence and properties of Clostridium difficile in hospitalized patients of Estonia. Reviews in Medical Microbiology, 8, S60−S61.
1.2.
1997
Oona, M.; Rägo, T.; Maaroos, H-I.; Mikelsaar, M.; Lõivukene, K.; Salminen, S.; Korhonen, H. (1997). Helicobacter pylory in children with abdominal complaints: has immune bovine colostrum some influence on gastritis? Alpe Adria Microbiology Journal, 6, 49−57.
1.2.
1997
Tapfer, H.; Liigant, A.; Talvik, R.; Roosar, P.; Hussar, Ü.; Mikelsaar, M.; Simovart, H.-E. (1997). Pathomorphologic responses in experimental sepsis. Papers on Anthropology, VII, 339−350.
1.2.
1997
Ormisson, Anne; Sepp, Epp; Siigur, Urmas; Varendi, Heili; Mikelsaar, Marika (1997). Impact of early life nutrition on growth and intestinal microflora composition in low-birth-weight infants. Scandinavian Journal of Nutrition, 41 (2), 71−74.
1.3.
1997
Sepp, E.; Lõivukene, K.; Naaber, P.; Kermes, K.; Kõljalg, S.; Julge, K.; Vasar, M.; Björksten, B.; Mikelsaar, M. (1997). Tervete ja allergiliste laste mikrofloora erinevused. Eesti Rohuteadlane, Lisa, 62−63.
1.1.
1996
Mandar, R.; Mikelsaar, M. (1996). Transmission of mother's microflora to the newborn at birth. Biology of the Neonate, 69 (1), 30−35.
1.1.
1996
Naaber, P.; Lehto, E.; Salminen, S.; Mikelsaar, M. (1996). Inhibition of adhesion of Clostridium difficile to Caco-2 cells. FEMS Immunology & Medical Microbiology, 14 (4), 205−209.
1.1.
1996
Koljalg, S.; VuopioVarkila, J.; Lyytikainen, O.; Mikelsaar, M.; Wadstrom, T. (1996). Cell surface properties of Acinetobacter baumannii. Apmis, 104 (9), 659−665.
1.2.
1996
Mikelsaar, M.; Mändar, R.; Maaroos, H.-I.; Päär, S.; Rägo, T.; Kisand, K.; Aleljung, P.; Wadström, T. (1996). Helicobacter pylori gastritis in children: a clinical, bacteriological, and morphological study. Microecology and Therapy, 22, 44−53.
1.3.
1996
Kõljalg, S.; Kermes, K.; Lõivukene, K.; Naaber, P.; Mikelsaar, M. (1996). Kirurgilisi infektsioone tekitavad mikroorganismid ja nende antibiootikumtundlikkus. Eesti Arst, lisa, 39−40.
1.3.
1996
Mändar, R.; Mikelsaar, M. (1996). Vaginal microflora during pregnancy. Alpe Adria Microbiology Journal, 5, 41−50.
1.2.
1995
Sepp, E.; Tamm, E.; Torm, S.; Lutsar, I.; Mikelsaar, M.; Salminen, S. (1995). Impact of a lactobacillus probiotic on the faecal microflora in children with shigellosis. Microecology and Therapy, 23, 74−80.
1.2.
1995
Naaber, P.; Mikelsaar, M. (1995). Antibiotic - compromised murine model of C. difficile infection. Microbial Ecology and Therapy, 25, 206−208.
1.2.
1995
Mikelsaar, M.; Sepp, E.; Mändar, R.; Ormisson, A. (1995). Criteria for evaluation of the faecal microflora. Microecology and Therapy, 23, 149−150.
1.2.
1995
Mändar, R.; Saag, H.; Peil, P.; Mikelsaar, M. (1995). Bacterial vaginosis during pregnancy. Microecology and Therapy, 23, 24−31.
1.3.
1994
Naaber, P.; Maimets, M.; Mikelsaar, M. (1994). Clostridium difficile põhjustatud diarröa I. Eesti Arst, 2, 122−124.
1.1.
1993
Sepp, E.; Mikelsaar, M.; Salminen, S. (1993). Effect of administration of lactobacillus-casei strain gg on the gastrointestinal microbiota of newborns. Microbial Ecology in Health and Disease, 6 (6), 309−314.
3.1.
1993
Mikelsaar, M.; Mändar, R. (1993). Development of individual lactic acid microflora in the human microbial ecosystem. S. Salminen; A. von Wright. Lactic Acid Bacteria (237−293). . New York: Marcel Dekker Inc.
1.1.
1990
Kolts, KK.; Mikelsaar, ME.; Maaroos, HIG. (1990). A method for isolation of campylobacter-pylori from gastrointestinal mucosa. Laboratornoe Delo, 2, 44.
1.1.
1990
Mikelsaar, ME.; Siigur, UK.; Lentsner, AA. (1990). Assessment of the fecal microflora quantitative composition. Laboratornoe Delo, 3, 62−66.
1.1.
1989
Tamm, AO.; Siigur, UK.; Mikelsaar, ME. (1989). Antibiotic influence on intestinal microflora and production of metabolites. Antibiotiki i Khimioterapiya, 34 (6), 409−414.
1.1.
1989
Lentsner, AA.; Lentsner, KP.; Mikelsaar, ME.; Turi, ME.; Troshin, AA.; Tark, ER.; Knyazev, VM.; Korolkov, VI.; Lizko, NN.; Petrova, LN. (1989). Species composition of the intestinal lactoflora of healthy rhesus macaques. Zhurnal Mikrobiologii, Epidemiologii i Immunologii, 6, 11−15.
1.1.
1989
Mikelsaar, ME.; Siigur, UK.; Tamm, AO. (1989). Microecological aspects of studies on the effect of antibacterial drugs on intestinal microflora. Antibiotiki i Khimioterapiya, 34 (6), 420−425.
1.2.
1989
Mikelsaar, M.; Sepp, E.; Kasesalu, R.; Kolts, K. (1989). Some Considerations on the Formation of normal Human Microflora during the First Year of Life. Wissenschaftliche Zeitschrift der Ernst-Moritz-Arndt-Universität Greifswald. Med. Reihe, 38, 27−30.
1.1.
1987
Mikelsaar, M.; Turi, M.; Lencner, H.; Kolts, K.; Kirch, R.; Lencner, A. (1987). Interrelations between mucosal and luminal microflora of gastrointestine. Nahrung-Food, 31, 449.
1.1.
1987
Tamm, AO.; Viya, MP.; Mikelsaar, ME.; Siigur, UK. (1987). Metabolites of intestinal microflora and diagnosis of intestine dysbiosis. Antibiotiki i Meditsinskaya Biotekhnologiya, 32 (3), 191−195.
1.1.
1987
Tamm, A.; Siigur, U.; Mikelsaar, M.; Vija, M. (1987). Output of bacterial metabolites as a diagnostic means. Nahrung-Food, 31, 485−492.
1.1.
1987
Lencner, A.; Lencner, H.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Turi, M. (1987). The defense function of the intestinal lactoflora. Nahrung-Food, 31, 405−411.
1.1.
1987
Lenzner, H.; Lenzner, A.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Türi, M.; Levkov, L. (1987). Laktoflora and colonization resistance. Antibiotiki i Meditdinskaya Biotekhnologiya, 32 (3), 173−179.
1.2.
1987
Lenzner, H.; Lenzner, A.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Türi, M. (1987). Zur Abwehrfunktion der Laktoflora des Verdauungstraktes. Die Nahrung, 31, 405−411.
5.1.
1986
Mikelsaar, M. (1986). The possibilities of balanced coexistence in the system organism and its microflora. Endocytobiosis and Cell Research, 3 (3), 350−350.
1.1.
1984
Mikelsaar, ME.; Tjuri, ME.; Valjaots, ME.; Lencner, AA. (1984). Anaerobic lumen and mucosal microflora of the gastrointestinal-tract. Nahrung-Food, 28, 727−733.
1.1.
1984
Lencner, AA.; Mikelsaar, ME.; Tjuri, ME.; Valjaots, ME.; Silov, VM.; Lizko, NN.; Legenkov, VI.; Reznikov, IM. (1984). The quantitative composition of the gut lactoflora before and after cosmic flights of different duration. Nahrung-Food, 28, 607−613.
1.1.
1981
Lentsner, AA.; Lentsner, HP.; Mikelsaar, ME.; Shilov, VM.; Lizko, NN.; Syrykh, GD.; Legenkov, VI. (1981). Examination of the digestive lactoflora of soyuz-13 and salyut-4 crew-members. Kosmicheskaya Biologiya i Aviakosmicheskaya Meditsina, 15 (4), 39−43.
1.1.
1981
Lentsner, AA.; Turi, ME.; Lentsner, HP.; Mikelsaar, ME.; Shilov, VM.; Lizko, NN.; Syrykh, GD. (1981). Study of the antibiotic-sensitivity of digestive lactobacilli of soyuz-13 and salyut-4 crewmembers. Kosmicheskaya Biologiya i Aviakosmicheskaya Meditsina, 15 (4), 36−39.
1.1.
1973
Lentsner, AA.; Shilov, VM.; Lizko, NN.; Mikelsaa, ME. (1973). Study of species composition of intestinal lactobacilli of man during long-term enclosure. Kosmicheskaya Biologiya i Meditsina, 7 (3), 76−80.

Tööstusomand

23.03.2021

Marika Mikelsaar

https://etis.ee/CV/Marika_Mikelsaar/eng
12.11.1938
737 4179
503 9989
marika.mikelsaar@ut.ee
16.05.1993−16.05.2016 Mikelsaar, Marika

Career

Institutions and positions
01.03.2021–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Project Manager in Science (0,25)
01.02.2016–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Department of Microbiology, Project Manager in Science (0,50)
2010–...   
University of Tartu, Faculty of Medicine, Department of Microbiology, Extraordinary Research Professor (1,00)
2003–...   
University of Tartu, Faculty of Medicine, Department of Microbiology, Professor emeritus (1,00)
1965-1968 Ph D studies by University of Tartu, dept. microbiology
1963-1965 residency by University of Tartu, dept. microbiology
01.12.2017–28.02.2021   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Project Manager in Science (0,30)
01.01.2016–31.01.2016   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Project Manager in Science (1,00)
09.02.2013–31.12.2015   
University of Tartu, Faculty of Medicine, Department of Microbiology, Project Manager in Science (1,00)
09.02.2010–08.02.2013   
University of Tartu, Faculty of Medicine, Department of Microbiology, Lead Research Fellow in Medical Biotechnology (1,00)
09.02.2007–08.02.2010   
University of Tartu, Faculty of Medicine, Department of Microbiology, Professor extraordinarius of Medical Biotechnology (1,00)
09.02.2004–08.02.2007   
University of Tartu, Faculty of Medicine, Department of Microbiology, Professor extraordinarius (1,00)
1993–2003   
University of Tartu, Faculty of Medicine, Department of Microbiology, Professor (1,00)
01.01.1991–31.12.1993   
Other staff
1979–1993   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Senior Researcher (1,00)
1969–1979   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Researcher (1,00)
 
 
Education
kõrgem
Higher education, University of Tartu, medical faculty 1963
 
 
R&D related managerial and administrative work
1995-1999 secretary of the medical council of tartu university
2008−2010   
Society for Microbial Ecology in Health and Disease ; president -elect
1993−2003   
1993-2003 Head of department of microbiology
1993−2003   
1993-2002 member of the medical council of Tartu university

Qualifications

Academic degrees
Marika Mikelsaar, Doctor's Degree, 1993, (sup) -, Evaluation of the microbial ecosystem in health and disease, Department of Microbiology, University of Tartu.
 
 
Honours & awards
2011, Marika Mikelsaar, Honorary Member of Tartu
2010, Marika Mikelsaar, National science prize for lifelong work
2008, Marika Mikelsaar, Worldwide female investigators and innovators golden medal form S-Korea
2008, Marika Mikelsaar, White Star III class decoration
2007, Marika Mikelsaar, European Union Women Inventors&Innovators Network (EUWIIN) Special recognition Award
2007, Marika Mikelsaar, Decoration of Tartu
2002, Marika Mikelsaar, National science prize in medicine
1994, Marika Mikelsaar, National science prize in medicine
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.2. Microbiology; SPECIFICATION: Human microbial ecology in health and disease and the correction of impact of microbiota with probiotics
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.2. Microbiology; SPECIFICATION: Clinical microbiology
ETIS CLASSIFICATION: 3. Health; 3.1. Biomedicine; SPECIFICATION: Human microbial ecology, chronic inflammatory processes, prevention and adjunct therapy with probiotics
 
 
Additional information
cand. med.
doctor of medical sciences
University of Tartu, 1969
University of Tartu, 1993

Projects in progress

Completed projects

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2021
Mikelsaar, Marika; Mändar, Reet. (2021). Commentary: Gut Microbiome and Space Travelers' Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions. Frontiers in Physiology, x. DOI: 10.3389/fphys.2021.651977 [forthcoming].
5.2.
2021
Ehrlich-Peets, Kersti; Rätsep, Merle; Vallas, Mirjam; Mikelsaar, Marika; Zilmer, Mihkel; Songisepp, Epp (2021). Probiotic multifunctional Lactobacillus plantarum strain Inducia® for food valorisation and health. FoodBalt 2021: Book of abstracts: 14th Baltic Conference on Food Science and Technology FoodBalt 2021 “Sustainable Food for Conscious Consumer”. Center of Food and Fermentation Technologies, 21−21.
1.1.
2020
Marika Mikelsaar, Jelena Stsepetova, Raik-Hiio Mikelsaar, Kai Truusalu, Imbi Smidt, Pirje Hütt, Merle Rätsep, Epp Songisepp (2020). Polyamines of human strain Lactobacillus plantarum Inducia induce modulation of innate immune markers. Journal of Functional Foods, 72, 1−9. DOI: 10.1016/j.jff.2020.104064.
1.3.
2020
Ainsaar, M.; Soidla, I.; Sepp, E.; Kõljalg, S.; Štšepetova,J.; Rööp, T.; Smidt, I.; Mikelsaar, M.; Mändar, R. (2020). Kelle poole pöördub abi saamiseks Eesti 100-aastane? [To whom 100-year-olds will turn for help in Estonia?]. Sotsiaaltöö, 3.
1.3.
2019
Mikelsaar, Marika; Lõivukene, Krista; Naaber, Paul; Mändar, Reet (2019). Helicobacter pyllori infektsioonide teaduspõhine diagnostika ja mikroobivastane ravi [Evidence based diagnostics and antimicrobial treatment of Helicobacter pylori infections]. Eesti Arst, 98 (7), 381−384.
5.2.
2019
Smidt, Imbi; Sepp, Epp; Hoidmets, Dagmar; Rööp, Tiiu; Mikelsaar, Marika; Mändar, Reet (2019). Probiootikumide selekteerimine nahainfektsioonide profülaktikaks. Eesti Arst, 98: Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2019. Eesti Arst, 34−34.
1.1.
2018
Sepp, Epp; Smidt, Imbi; Stsepetova, Jelena; Roop, Tiiu; Hutt, Pirje; Ratsep, Merle; Mikelsaar, Marika (2018). The effect of Lactobacillus fermentum ME-3 on the intestinal microbiota and urine polyamines content: A double-blind placebo-controlled pilot trial. Journal of Functional Foods, 48, 430−438. DOI: 10.1016/j.jff.2018.04.053.
1.3.
2018
Mändar, Reet; Mändar, Hugo; Rööp, Tiiu; Mikelsaar, Marika. (2018). Inimese mikrobioota biopank Tartu Ülikoolis. Eesti Arst, 97 (3), 170−172.
1.3.
2018
Mikelsaar, Marika (2018). Uut probiootikumidest. Perearst, 2, 25−30.
1.1.
2017
Rätsep M.; Kõljalg S.; Sepp E.; Smidt I.; Truusalu K.; Songisepp E.; Stsepetova J.; Naaber P.; Mikelsaar R.H.; Mikelsaar M. (2017). A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection. Anaerobe, 47, 94−103. DOI: 10.1016/j.anaerobe.2017.03.019.
2.4.
2017
Lutsar, Irja; Mändar, Reet; Mikelsaar, Marika; Karki, Tõnis; Brilene, Tatjana; Kõljalg, Siiri; Meriste, Sirli; Sepp, Epp; Avi, Radko; Truusalu, Kai; Parm, Ülle (2017). Meditsiiniline Mikrobioloogia. Üldmikrobioloogia [Medical Microbiology]. Tartu: TÜ kirjastus.
3.2.
2017
Mikelsaar, M. (2017). Teadmiste spiraal. Sajand inimese mikroobiökoloogiat Tartu Ülikoolis [A spiral of knowledge. A century of human microbial ecology at the university of Tartu.]. Lea Leppik (Toim.). Tartu Ülikooli ajaloo küsimusi XLV. Muutuste sajand Eesti meditsiinis. (102-117.). Tartu: Tartu Ülikooli muuseum.
3.2.
2017
Maaroos, H-I.; Mikelsaar, M.; Vorobjova,T. (2017). Helicobacter pylori avastamise lugu: kliinilised, immunoloogilised ja mikrobioloogilised aspektid. Eesti uurijate panus Nobeli auhinnaga pärjatud uuringutesse. Lea Leppik (Toim.). Muutuste sajand Eesti meditsiinis (76−101). Tartu Ülikooli Kirjastus.
1.1.
2016
Andersen, KK.; Strokappe, NM.; Hultber1, A.; Truusalu, K.; Smidt, I.; Mikelsaar, RH.; Mikelsaar, MM.; Verrips, T.; Hammarström, L.; Marcotte, H. (2016). Neutralization of Clostridium difficile toxin B mediated by engineered lactobacilli producing single domain antibodies. Infection and Immunity, 84 (2), 395−406. DOI: 10.1128/IAI.00870-15.
3.1.
2016
Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena; Songisepp, Epp; Mändar, Reet. (2016). Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population. Advances in Experimental Medicine and Biology, 932, 1−64. DOI: 10.1007/5584_2016_3.
1.1.
2015
Le Roy, Caroline; Štšepetova, Jelena; Sepp, Epp; Songisepp, Epp; Claus, Sandrine; Mikelsaar, Marika. (2015). New insights into the inpact of Lactobacillus population on host-bacteria metabolic interplay. Oncotarget, 6 (31), 1−12. DOI: 10.18632/oncotarget.5906.
1.1.
2015
Hütt, Pirje; Songisepp, Epp; Rätsep, Merle; Mahlapuu, Riina; Kilk, Kilk; Mikelsaar, Marika. (2015). Impact of probiotic L. plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults. Beneficial Microbes, 6 (3), 1−12. DOI: 10.3920/BM2014.0035.
1.2.
2015
Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena; Hütt, Pirje; Zilmer, Kersti; Kullisaar, Tiiu; Zilamer, Mihkel. (2015). Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults. BMC Nutrition, 1 (27), 1−13. DOI: 10.1186/s40795-015-0020-z.
5.2.
2015
Truusalu, Kai; Vainumäe, Inga; Stsepetova, Jelena; Smidt, Imbi; Sepp, Epp; Mikelsaar, Marika; Kõljalg, Siiri (2015). The impact of the initial antibiotic treatment to subsequent recurrences in childhood urinary tract infection caused by Escherichia coli: beta-lactams vs gentamicin. In: . ECCMID 2015 Copenhagen, Denmark, 25-28 April 2015. ECCMID 2015 Copenhagen, Denmark, 25-28 April 2015.
5.2.
2015
Štšepetova Jelena;  Šebunova Natalja; Larionova Anneli; Voor Tiia; Rööp Tiiu;  Mikelsaar Maarika; Mändar Reet; Sepp Epp  (2015). "Quantitative changes of Clostridium sp.in human intestinal tract of different age groups.“. FEMS konverents, Maastricht, Holland, 07.06. – 11.06.2015. FEMS.
5.2.
2015
Šebunova, Natalja;  Larionova, Anneli; Voor, Tiia; Rööp, Tiiu;  Mikelsaar, Marika; Sepp, Epp; Štšepetova, Jelena (2015). "Molecular quantitative analysis of human intestinal microbiota in different age groups.". 2nd Microbiome R&D and Business Collaboration Forum: Europe. London, UK, 07.05. – 08.05.2015. Global Engage.
1.1.
2014
Kõljalg, Siiri; Truusalu, Kai; Štšepetova, Jelena; Pai, Kristiine; Vainumäe, Inga; Sepp, Epp; Mikelsaar, Marika (2014). The Escherichia coli phylogenetic group B2 with integrons prevails in childhood recurrent urinary tract infections. Apmis, 122 (5), 452−458. DOI: 10.1111/apm.12167.
1.1.
2014
Talja, Ija; Kubo, Anna-Liisa; Veijola, Riitta; Knip, Mikael; Simell, Olli; Ilonen, Jorma; Vaha-Makila, Mari; Sepp, Epp; Mikelsaar, Marika; Utt, Meeme; Uibo, Raivo (2014). Antibodies to Lactobacilli and Bifidobacteria in Young Children with Different Propensity to Develop Islet Autoimmunity. Journal of Immunology Research, ARTN 325938. DOI: 10.1155/2014/325938.
5.1.
2014
Truusalu, K; Smidt, I; Hütt, P; Stsepetova, J; Vainumäe, I; Sepp, E; Mikelsaar, M; Kõljalg, S. (2014). Comparison of phylogenetic groups, antibacterial resistance and integron containment of Escherichia coli from initial episode of childhood urinary tract infections with different outcomes. 24th European Congress of Clinical Microbiology and Infectious Diseases in Barcelona, Spain, 10 – 13 May 2014.. x, x.
5.2.
2014
Štšepetova, Jelena; Oopkaup, Helen; Smidt, Imbi; Mikelsaar, Marika. (2014). The ability of intestinal Lactobacillus sp.to produce putrescine from agmatine. The Intestinal Microbiota and Gut Health: Contribution of the Diet, Bacterial Metabolites, Host Interactions and Impact on Health and Disease. x, 171−173.
5.2.
2014
Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika; Mändar, Reet. (2014). Human Microbiota Biobank. 2nd World Congress on Targeting Microbiota, Institut Pasteur, Paris, France, October 16-17, 2014..
5.2.
2014
Mändar, Reet; Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika. (2014). Microbiota Collection at University of Tartu: Human Microbiota Biobank (HUMB). International Scientific Conference on Probiotics and Prebiotics - IPC2014, Budapest, Hungary, 24 – 26 June, 2014.
5.2.
2014
Štšepetova, J.; Šebunova, N.; Larionova, A.; Voor, T.; Rööp, T.; Mikelsaar, M.; Sepp, E. (2014). c. 2014 ENGIHR Conference: The Gut Microbiota Throughout Life, Max Rubner-Insitut, Karlsruhe, Germany, September 24-26, 2014.
5.2.
2014
Hütt, P., Sepp, E.; Truusalu, K.; Kullisaar, T.; Zilmer, K.; Zilmer, M.; Mikelsaar, M. (2014). Effect of consumption of probiotic kefir comprising Lactobacillus fermentum strain ME-3 on blood indices of healthy volunteers. ECCMID - European Congress on Clinical Microbiology and Infectious Diseases; Barcelona, Spain; May 10-13, 2014.
5.2.
2014
Štšepetova Jelena; Šebunova Natalja; Larionova Anneli; Voor Tiia; Rööp Tiiu; Mikelsaar Maarika; Sepp Epp. (2014). "Quantitative changes of Lactobacillus and Bifidobacterium sp. in human intestinal tract of different age groups.". The European Network for Gastrointestinal Health Research), Karlsruhe, Germany, 24.09–26.09.2014.. http://www.engihr.eu/2014-engihr-conference/: Max Rubner Institute.
1.1.
2013
Sharafedtinov, Khaider; Plotnikova, Oksana; Alexeeva, Ravilay; Sentsova, Tatjana; Songisepp, Epp; Stsepetova, Jelena; Smidt, Imbi; Mikelsaar, Marika (2013). Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study. Nutrition Journal, 12, 138−159. DOI: 10.1186/1475-2891-12-138.
5.2.
2013
Štšepetova, J; Oopkaup, H; Smidt, I; Mikelsaar, M. (2013). The ability of intestinal Lactobacillus sp. to produce putrescine from agmatine. European Network for gastrointestinal health research: The intaestinal Microbiota and Gut Health: Contribution of the Diet, Bacterial Metabolites, Host interactions and Impact on Health and Diseases. x, 171−173.
6.3.
2013
Leppik, Lea; Mikelsaar, Marika (2013). Kosmonaudid, laktobatsillid ja Tartu. Horisont, 3, 47−48.
1.1.
2012
Songisepp, E.; Hütt, P.; Rätsep, M.; Shkut, E.; Kõljalg, S.; Truusalu, K.; Stsepetova, J.; Smidt, I.; Kolk, H.; Zagura, M.; Mikelsaar, M. (2012). Safety of probiotic cheese containing Lactobacillus plantarum Tensia according to a variety of health indices in different age groups. Journal of Dairy Science, 95 (10), 5495−5509. DOI: 10.3168/jds.2011-4756.
1.2.
2012
Mikelsaar, Marika; Hütt, Pirje; Stsepetova, Jelena; Smidt, imbi; Shkut, Elena; Rätsep, Merle; Zilmer, Mihkel; Songisepp, Epp (2012). Probiotic Heart cheese "Harmony" comprising L. plantarum Tensia influences blood pressure and metabolic health indices (in Russian). Voprossõ pitanija, 81 (3), 74−81.
5.2.
2012
Rööp, Tiiu; Mändar, Hugo; Mikelsaar, Marika; Mändar, Reet. (2012). Human Microbiota Biobank (HUMB) at University of Tartu, Estonia. 31st annual meeting of the European Culture Collections' Organization, Braga, Portugal, 14-15 June 2012..
5.2.
2012
Kõljalg, S.; Truusalu, K.; Stsepetova, J.; Pai, K.; Vainumäe, I.; Hütt, P.; Smidt, I.; Mändar, R.; Sepp, E.; Mikelsaar, M. (2012). The role of phylogenetic groups of Escherichia coli in childhood recurrent urinary tract infections. 22nd European Congress ofClinical Microbiology and Infectious Diseases, London, United Kingdom, 31 March – 3 April 2012.
1.1.
2011
Kullisaar, Tiiu; Shepetova, Jelena; Zilmer, Kersti; Songisepp, Epp; Rehema, Aune; Mikelsaar, Marika; Zilmer, Mihkel (2011). An antioxidant probiotic reduces postprandial lipemia and oxidative stress. Central European Journal of Biology, 32−40. DOI: 10.2478/s11535-010-0103-4.
1.1.
2011
Uibo, R.; Panarina, M.; Teesalu, K.; Talja, I.; Sepp, E.; Utt, M.; Mikelsaar, M.; Heilman, K.; Uibo, O.; Vorobjova, T. (2011). Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity? Cellular and Molecular Immunology, 8 (2), 150−156.
1.1.
2011
Stsepetova, Jelena; Sepp, Epp; Kolk, Helgi; Loivukene, Krista; Songisepp, Epp; Mikelsaar, Marika (2011). Diversity and metabolic impact of intestinal Lactobacillus sp. in healthy adults and the elderly. British Journal Of Nutrition, 105 (8), 1235−1244. DOI: 10.1017/S0007114510004770.
1.1.
2011
Mikelsaar, M. (2011). Human microbial ecology: lactobacilli, probiotics, selective decontamination. Anaerobe, 463−467. DOI: 10.1016/j.anaerobe.2011.07.005.
1.2.
2011
Hütt, P.; Stsepetova, J.; Alvarez, B.; Mändar, R.; Krogh-Andersen, K.r; Marcotte, H.; Hammarström, L.; Mikelsaar, M. (2011). Safety and persistence of orally administered human Lactobacillus sp. strains in healthy adults. Beneficial Microbes, 2, 79−90.
1.2.
2011
Mikelsaar, Marika; Lazar, Veronica; Onderdonk, Andrew Bruce ; Donelli, Gianfranco (2011). Do probiotic preparations for humans really have efficacy? Microbial Ecology in Health and Disease, 22, 10128. DOI: 10.3402/mehd.v22i0.10128.
5.2.
2011
Songisepp, Epp; Hütt, Pirje; Rätsep, Merle; Shkut, Elena; Zilmer, Mihkel; Kõljalg, Siiri; Truusalu, Kai; Smidt, Imbi; i Kolk, Helg; Zagura, Maksim; Mikelsaar, Marika (2011). Safety of a probiotic cheese comprising L. plantarum TENSIA according variety of health indices in different age groups. 6th Probiotics Prebiotics New Foods. , 48.
1.1.
2010
Mikelsaar, M.; Stsepetova, J.; Hütt, P.; Kolk, H.; Sepp, E.; Lõivukene, K.; Zilmer, K.; Zilmer, M. (2010). Intestinal Lactobacillus sp. is associated with some cellular and metabolic characteristics of blood in elderly people. Anaerobe, 16 (3), 240−246. DOI: 10.1016/j.anaerobe.2010.03.001.
1.1.
2010
Truusalu, K.; Kullisaar, T.; Hütt, P.; Mahlapuu, R.; Aunapuu, M.; Arend, A.; Zilmer, M.; Mikelsaar, R.; Mikelsaar, M. (2010). Immunological, antioxidative, and morphological response in combined treatment of ofloxacin and Lactobacillus fermentum ME-3 probiotic in Salmonella Typhimurium murine model. Apmis, Nov; 118 (11), 864−72.
1.1.
2010
Kõll, Piret; Mändar, Reet; Smidt, Imbi; Hütt, Pirje; Truusalu, Kai; Mikelsaar, Raik-Hiio; Shchepetova, Jelena; Krogh-Andersen, Kasper; Marcotte, Harold; Hammarström, Lennar; Mikelsaar, Marika. (2010). Screening and evaluation of human intestinal lactobacilli for the development of novel gastrointestinal probiotics. Current Microbiology, 61 (6), 560−566. DOI: 10.1007/s00284-010-9653-y.
1.1.
2010
Prangli, AL; Utt, M; Talja, I; Sepp, E; Mikelsaar, M; Rajasalu, T; Uibo, O; Tillmann, V; Uibo, R. (2010). Antigenic proteins of Lactobacillus acidophilus that are recognised by serum IgG antibodies in children with type 1 diabetes and coeliac disease. Pediatric Allergy and Immunology, 21 (4), e772−e779. DOI: 10.1111/j.1399-3038.2009.00904.x.
1.1.
2010
Kullisaar, T.; Songisepp, E.; Aunapuu, M.; Kilk, K.; Arend, A.; Mikelsaar, M.; Rehema, A.; Zilmer, M. (2010). Complete Glutathione System in Probiotic L. fermentum ME-3. Applied Biochemistry and Microbiology, 46 (5), 481−486. DOI: 10.1134/S0003683810050030.
5.2.
2010
Naaber, P.; Truusalu, K.; Smidt, I.; Kõljalg, S.; Sepp, E.; Hütt, P.; Mändar, R.; Mikelsaar, M. (2010). Protective effect of xylitol and lactobacilli against Clostridium difficile infection in hamster model. Clinical Microbiology and Infection, 16 : 20th ECCMID, Vienna, Austria 10-13 April 2010. (2).
1.1.
2009
Sepp, E.; Stsepetova, J.; Lõivukene, K.; Truusalu, K.; Kõljalg, S.; Naaber, P.; Mikelsaar, M. (2009). The occurrence of antimicrobial resistance and class 1 integrons among commensal Escherichia coli isolates from infants and elderly persons. Annals of Clinical Microbiology and Antimicrobials, 8 (34), 1−6.
1.1.
2009
Hütt, P.; Andreson, H.; Kullisaar, T.; Vihalemm, T.; Unt, E.; Kals, J.; Kampus, P.; Zilmer, M.; Mikelsaar, M. (2009). Effects of a synbiotic product on blood antioxidative activity in subjects colonized with Helicobacter pylori. Letters in Applied Microbiology, 48 (6), 797−800. DOI: 10.1111/j.1472-765X.2009.02607.x.
1.1.
2009
Kõljalg, S.; Truusalu, K.; Vainumäe, I.; Štšepetova, J.; Sepp, E.; Mikelsaar, M. (2009). Persistence of Escherichia coli clones and phenotypic and genotypic antibiotic resistance in recurrent tract infections in childhood. Journal of Clinical Microbiology, 47 (1), 99−105. DOI: 10.1128/JCM.01419-08.
1.2.
2009
Mikelsaar, M.; Zilmer, M. (2009). Lactobacillus fermentum ME-3 - an antimicrobial and antioxidative probiotic. Microbial Ecology in Health and Disease, 21 (1), 1−27. DOI: 10.1080/08910600902815561.
3.2.
2009
Hütt, P.; Songisepp, E.; Rätsep , M.; Shkut, E.; Mikelsaar, M. (2009). L. plantarum TENSIA comprising probiotic cheese with hypotensive effect. Cibus. Ciornale Dell’alimentazione e patologie correlate, 5. Itaalia, Rooma: University Press S.r.l. Roma, 43.
3.4.
2009
Songisepp, E.; Zilmer, M.; Hütt, P., Rätsep, M.; Utt, M.; Üksti, J.; Kõljalg, S.; Zilmer, K.; Mikelsaar, M. (2009). Lactobacillus plantarum TENSIA™ (DSM 21380) as a novel probiotic. Гастроэнтерология Санкт-Петербурга, 4. , A25.
3.5.
2009
Štšepetova, J.; Sepp, E.; Kolk, H.; Lõivukene, K.; Hütt, P.; Songisepp, E.; Mikelsaar, M. (2009). Soole laktobatsillid tervetel täiskasvanutel ja eakatel isikutel. Eest Arst, 9. , 604−605.
5.2.
2009
Hütt, P.; Alvarez, B.; Stsepetova, J.; Truusalu, K.; Mändar, R.; Kõll, P.; Marcotte, H.; Krogh-Andersen, K.; Mikelsaar, M. (2009). Safety and persistence of orally administered human Lactobacillis sp. starins in health adults. Гастроэнтерология Санкт-Петербурга, 4, A11−A11.
5.2.
2009
Štšepetova, J.; Kullisaar, T.; Songisepp, E.; Zilmer, M.; Mikelsaar, M. (2009). Design of L. fermentum ME-3 strain-specific primersfor detecting the cell number in human feces by real-time PCR. Гастроэнтерология Санкт-Петербурга, 4, A26−A27.
5.2.
2009
Sepp, E.; Lõivukene, K.; Julge, K.; Voor, T.; Mikelsaar, M. (2009). How gut microbiotais is associated to children overweight. Gastroenterologiia Sankt-Peterburga, 4: XXXII Inernational Congress of the Society for Microbial Ecology and Disease; Sankt Peterburg, Russia; 29.-30.10.2009. , A23.
5.2.
2009
Jaanimäe, L.; Sepp, E.; Štšepetova, J.; Kõljalg, S.; Mikelsaar, M. (2009). Eesti nosokomiaalse Clostridium difficile tundlikkus antibiootikumidele. Eesti Arst, 9. , 583.
6.7.
2009
Mikelsaar, M.; Songisepp, E.; Smidt, I.; Stsepetova J., Hütt, P.; Zilmer, M.; Truusalu, K.; Kilk, K. (2009). PCT/EE2009/000006 "Isolated Lactobacillus plantarum strain Inducia DSM 21379 as probiotic that enhances natural immunity and food products and medicinal preparations comprising it". Espacenet, x−x.
6.7.
2009
Songisepp, E.; Mikelsaar, M.; Rätsep, M.; Zilmer, M.; Zilmer , K.; Üksti, J.; Kõljalg, S. (2009). Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Tensia DSM 21380 kui antimikroobne ja antihüpertensiivne probiotik, toiduprodukt ja Komposition mis sisaldab vastavat mikroorganismi ja selle mikroorganismi kasutus antihüpertensiivse ravimi valmistamiseks ja meetod patogeenide ja mitte-starter laktobatsillide allasurumiseks toiduproduktis. Espacenet, x−x.
1.1.
2008
Truusalu, K.; Mikelsaar, R-H.; Naaber, P.; Karki, T.; Kullisaar, T.; Zilmer, M.; Mikelsaar, M. (2008). Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin. BMC Microbiology, 8 (132), 1−6. DOI: 10.1186/1471-2180-8-132.
1.1.
2008
Kaur, S.; Kullisaar, T.; Mikelsaar, M.; Eisen, M.; Rehema, A.; Vihalemm, T.; Zilmer, K.; Zilmer, M. (2008). Successful management of mild atopic dermatitis in adults with probiotics and emollients. Central European Journal of Medicine, 3, 215−220.
1.1.
2008
Kõll, P.; Mändar, R.; Marcotte, H.; Leibur, E.; Mikelsaar, M.; Hammarström, L. (2008). Characterization of oral lactobacilli as potential probiotics for oral health. Oral Microbiology and Immunology, 23 (2), 139−147. DOI: 10.1111/j.1399-302X.2007.00402.x.
1.2.
2008
Mikelsaar, M.; Hütt, P.; Kullisaar, T.; Zilmer, K.; Zilmer, M. (2008). Double benefit claims for antimicrobial and antioxidative probiotic. Microbial Ecology in Health and Disease, 20 (4), 184−188. DOI: 10.1080/08910600802408178.
3.4.
2008
Kullisaar, T.; Mikelsaar, M.; Kaur, S.; Songisepp, E.; Zilmer, K.; Hütt, P.; Lukmann, A.; Maaroos, J.; Kals, J.; Zilmer, M. (2008). Probiotics, oxidative stress, inflammation and diseases. Proceedings of the 2008 Joint Central European Congress, 4th Central European Congress on Food 6th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists, 1: The 2008 Joint Central European Congress, 4th Central European Congress on Food 6th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists; Croatia; 15-17 May 2008. Central European Science JournalS, 367−373.
3.5.
2008
Stsepetova J, Sepp E, Julge K, Mikelsaar M. (2008). Intestinal microbiota in non-allergic ja allergic 5-year-old Estonian children. 2nd Baltic Allergy Congress, Programme and abstract book: 2nd Baltic Allergy Congress, Tallinn, 23.-24. mai 2008. Tallinn, 78.
5.1.
2008
Hütt, P; Unt, E; Stsepetova, J; Smidt, I; Kullisaar, T; Zilmer, M; Mikelsaar, M. (2008). H-pylori colonization is associated with general oxidative stress-related and inflammatory markers. Absract Book of 21st International Worksop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer, 5: 21st International Worksop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer, 18-20.09.2008, Riga. HELICOBACTER , 395−395. (13).
5.2.
2008
K. Truusalu, RH. Mikelsaar, T. Kullisaar, M. Aunapuu, A. Arend, M. Zilmer, M. Mikelsaar (2008). Factors involved in combined treatment with probiotic and fluorokinolone in Salmonella Typhimurium murine infection. 18 ECCMID, Barcelona 20-24.04.08. Hispaania.
5.2.
2008
Truusalu, K.; Kõljalg, S.; Stsepetova, J.; Drell, T.; Vainumäe, I.; Sepp, E.; Mikelsaar, M. (2008). Persistence of Escherichia coli clones and resistance genes in recurrent urinary tract infections in children. 18th ECCMID; Barcelona; 20-24.04.2008. Hispaania, Barcelona.
5.2.
2008
Songisepp, E.; Mikelsaar, M.; Zilmer, M.; Hütt, P.; Smidt, I.; Stsepetova, J.; Truusalu, K.; Rätsep, M.; Kilk, K.; Utt, M.; Üksti, J.; Kõljalg, S., Zilmer, K. (2008). Lactobacillus plantarum TENSIA (DSM 21380) and L. plantarum INDUCIA (DSM 21379) as novel probiotics. FIL-IDF World Dairy Summit, Mecixo City, Mexico, 11-14 November 2008. Mexico City.
5.2.
2008
Stsepetova, J.; Kõljalg, S.; Sepp, E.; Lõivukene, K.; Songisepp, E.; Rätsep, M.; Mikelsaar, M. (2008). Antibiotic susceptibility pattern and tetracycline resistance of Lactobacillus strains of different origin. Clinical Microbiology and Infection, 14: 18th European Congress of Clinical Microbiology and Infectious Diseases. , Abstract number: P1210. (S7).
6.7.
2008
Mikelsaar, M.; Songisepp, E.; Smidt, I.; Stsepetova, J.; l Zilmer, M.; Hütt, P.; Truusalu, K.; Kilk, K. (2008). Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Inducia DSM 21379 kui organismi loomulikku kaitsevõimet tõstev probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine rakulist immuunsust tõstva ravimi valmistamiseks [Isolated microorganism strain Lactobacillus plantarum Inducia DSM 21379 as probiotic enhancing natural immunity of organism, food product and composition comprising said microorganism and use of said microorganism for production of medicine for enhancing of cellular immunity].
1.1.
2007
Štšepetova, J.; Sepp, E.; Julge, K.; Vaughan, E.; Mikelsaar, M.; de Vos, W.M. (2007). Molecularly assessed shifts of Bifidobacterium ssp. and less diverse microbial communities are characteristic of 5-year-old allergic children. FEMS Immunology & Medical Microbiology, 51 (2), 260−269.
1.1.
2007
Andreson, H.; Sillakivi, T.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2007). Persistence of Helicobacter pylori infection in patients with peptic ulcer perforation. Scandinavian Journal of Gastroenterology, 42 (3), 324−329. DOI: 10.1080/00365520600930859.
3.4.
2007
Hütt, Pirje; Songisepp, Epp; Mikelsaar, Marika (2007). Antagonistic Activity of Lactobacillus plantarum Strains Against Enteropathogens. VTT Symposium, 248: The 1st SAFOODNET seminar ‘Microbial contaminants & Contamination routes in food industry’ Food safety and hygiene networking FP6-022808-2006. Espoo, VTT, January 22-23, 2007. Ed. Wirtanen, G.; Salo, S. VTT (Valtion Teknillinen Tutkimuskesk) TECHNICAL RESEARCH CENTRE, 72−73.
3.4.
2007
Mikelsaar, M. (2007). Enteric pathogens- prevalence in food products and mechanisms of suppression by probiotic lactic acid bacteria. In: Wirtanen, G.; Salo, S. (Ed.). Food safety and hygiene networking FP6-022808-2006. SAFOODNET (31−35). . Helsinki: Finnish Academy Tech Sci. (Technical research centre of Finland (VTT) symposium; 248).
3.4.
2007
Mikelsaar, M. (2007). Impact of composition and metabolites of intestinal microbiota on foodborne infections. In: Wirtanen, G.; Salo, S. (Ed.). Food safety and hygiene networking FP6-022808-2006. SAFOODNET. Technical research centre of Finland (VTT) symposium 248, ed. G. Wirtanen, S. Salo, 2007, Helsinki (24−27). . Espoo, Helsinki: Finnish Academy Tech Sci. (VTT Symposium; 248).
3.5.
2007
Songisepp, E.; Rätsep, M.; Üksti, J.; Zilmer, K.; Hütt, P.; Mikelsaar, M. (2007). The improvement of cheese quality with human Lactobacillus plantarum additive. 1st open seminary arranged by SAFOODNET “Microbial Contaminants and contamination routes in food industry”; Espoo; Finland; January 22-23, 2007.
3.5.
2007
Mikelsaar, M. (2007). The evidence for microbiological role as triggers of exacerbations and modifiers of the natural history of asthma. In: ERS School Postgraduate Course PG24-GRACE full-day course. From cough to asthma: the role of infection (33−49). . European Respiratory society (ESCMID).
3.5.
2007
Kullisaar, T.; Zilmer, K.; Mikelsaar, M.; Songisepp, E.; Zilmer, M. (2007). Consumption of antioxidative probiotic L. fermentum ME-3 enriched kefir has beneficial impact on both postprandial profile and postprandial oxidative stress. Kliiniline toitumine (vene keeles), 1-2: International Congress on Probiotics, Prebiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects; St. Petersburg, Russia; May 15-16, 2007. Peterburg: Medlain-Medina, A6.
5.1.
2007
Saulnier, D.M.A.; Hutt, P.; Mikelsaar, M., Bosscher, D.; Gibson, G.; Kolida, S. (2007). Effects of a synbiotic on biomarkers of oxidative stress and faecal microbiota in healthy adults: results of a cross-over double-blind placebo-controlled trial. Proceedings of the Nutrition Society, 66. , 101A.
5.2.
2007
Stsepetova, J.; Sepp, E.; Lõivukene, K.; Kolk, H.; Mikelsaar, M. (2007). Individual diversity of intestinal lactobatsilli in healthy elderly. Kliiniline toitumine (vene keeles), 1-2: Probiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects; St. Petersburg, Russia; May 15-16. Peterburg: Medlain-Medina, A15.
5.2.
2007
Smidt, I.; Stsepetova, J.; Hütt, P.; Sepp, E.; Mikelsaar, M. (2007). Evaluation of biogenic amines in urine after synbiotic consumption. Klinitseskoje pitanije, 1-2: Probiotics, Synbiotics and Functional Foods: Scientific and Clinical Aspects, May 15-16, 2007 Peterburg, Russia. Peterburg: Medlain-Medina, A13−A14.
5.2.
2007
Mikelsaar, R.-H.; Truusalu, K.; Mikelsaar, M. (2007). Probiootilise laktobatsilli ja ofloksatsiini sünergeetiline efekt hiire tüüfuse mudelis. 9. Eesti Arst, 695.
5.2.
2007
Truusalu, K.; Mikelsaar, R.-H.; Naaber, P.; Karki, T.; Kullisaar, T.; Zilmer, M.; Mikelsaar, M. (2007). Probiotic Lactobacillus Fermentum ME-3 ehances ofloxacin effect on Salmonelle Typhimurium infection in a murine model. Kliiniline toitumine (vene keeles), 1-2: Probiotics, Synbiotics and Functional Foods; Scientific and Clinical Aspects; May 15-16. St. Peterburg: Medlain-Medina, A16.
5.2.
2007
Hütt, P.; Songisepp, E.; Guidas, M.; Tamme, T.; Ormanci, Fatma, Seda; Ayaz, N. D.; Korel, F.; Aarnisalo, K.; Hradecká, H.; Mikelsaar, M. (2007). Antimicrobial effects in food and prevention of contamination in food industry. VTT Symposium, 248: The 1st SAFOODNET seminar ‘Microbial contaminants & Contamination routes in food industry’ Food safety and hygiene networking FP6-022808-2006. Espoo,Finland January 22-23 2007. Ed. Wirtanen, G.; Salo, S. VTT Technical Research Centre of Finland, 159−170.
6.2.
2007
Lutsar, I.; Mikelsaar, M.; Karki, T. (2007). Meditsiiniline mikrobioloogia II. Tartu: Tartu Ülikooli Kirjastus.
1.1.
2006
Hütt, P.; Shchepetova, J.; Lõivukene, K.; Kullisaar, T.; Mikelsaar, M. (2006). Antagonistic activity of probiotic lactobacilli and bifidobacteria against entero- and uropathogens. Journal of Applied Microbiology, 100 (6), 1324−1332.
1.1.
2006
Marcotte, H.; Koll-Klais, P.; Hultberg, A.; Zhao, Y.; Mikelsaar, M.; Hammarstrom, L. (2006). Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus. Journal of Applied Microbiology, 100 (2), 256−263.
3.1.
2006
Sepp, E.; Voor, T.; Julge, K.; Lõivukene, K.; Björksten, B.; Mikelsaar, M. (2006). Ia intestinal microbiota bound up with changing lifestyle? In: A. Mendez-Vilas (Ed.). Modern Multidisciplinary Applied Microbiology: Exploiting Microbes and Their Interactions (708−712). . Germany: Wiley.
5.2.
2006
Štšepetova, J.; Sepp, E.; Truusalu, K.; Lõivukene, K.; Hütt, P.; Songisepp, E.; Mikelsaar, M. (2006). The prevalence of mobile gene cassettes in indigenous gut microbiota and dairy starter bacteria. Reproduction Nutrition Development, 46: Gut Microbiolology - Research to Improve Health, Immune Response and Nutrition, Aberdeen, Scotland, UK; 21-23 June, 2006. , S31.
5.2.
2006
Hütt, P.; Songisepp, E.; Mikelsaar, M. (2006). Antagonistic activity of putative probiotic Lactobacillus strains against enteropathogens. 13th World Congress of Food Science and Technology "Food is Life"; Nantes, France; 17-21 September, 2006.
5.2.
2006
Hütt, P.; Stsepetova, J.; Kullisaar, T.; Kals, J.; Zilmer, M.; Mikelsaar, M. (2006). Positive effect of synbiotic consumption in healthy volunteers. 3rd Central European Congress on Food; Sofia, Bulgaria; 22-24 May, 2006.
5.2.
2006
Štšepetova, Jelena; Sepp, Epp; Truusalu, Kai; Lõivukene, Krista; Hütt, Pirje; Songisepp, Epp; Mikelsaar, Marika (2006). Esimese klassi integronide esinemine indigeense E. coli ja toiduainetetööstuses kasutatavatel piimhapet produtseerivatel bakteritel. Eesti Arst, 9, 635.
5.2.
2006
Kõll, P.; Mändar, R.; Marcotte, H.; Leibur, E.; Mikelsaar, M.; Hammarström, L. (2006). Characterization of oral lactobacilli as potential probiotics. IADR-PEF. , 94.
5.2.
2006
Kõll, P.; Mändar, R.; Smidt, I.; Mikelsaar, M. (2006). Characterization of intestinal lactobacilli as potential second-generation probiotics. ECCMID. , 76.
5.2.
2006
Prangli, A.-L.; Utt, M.; Sepp, E.; Mikelsaar, M.; Uibo, O.; Tillmann, V.; Oona, M.; Rajasalu, T.; Talja, I.; Uibo, R. (2006). Laktobatsillivastaste antikehade määramine seerumis immunoblotmeetodiga. Eesti Arst, 85 (9), 643.
5.2.
2006
Truusalu, K.; Sepp, E.; Shchepetova, L.; Naaber, P.; Stroo, K.; Sepp, K.; Mikelsaar, M. (2006). Prevalence of class 1 integrons and MIC values in indigenous and pathogenic E. coli strains in different age groups. 16th European Congress of Clinical Microbiology and Infectious Diseases: ESCMID; Nice, France; 1-4 April, 2006. , P939.
6.2.
2006
Mikelsaar, M.; Karki, T.; Lutsar, I.; Mändar, R. (2006). Meditsiiniline mikrobioloogia I [Medical Microbiology Vol.1.]. Tartu: Tartu Ülikooli Kirjastus.
6.2.
2006
Mikelsaar, M.; Karki, T.; Lutsar, I.; Mändar, R. (2006). Meditsiiniline mikrobioloogia I osa. Tartu: Tartu Ülikooli Kirjastus.
1.1.
2005
Koll-Klais, P.; Mandar, R.; Leibur, E.; Marcotte, H.; Hammarstrom, L.; Mikelsaar, M. (2005). Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiology and Immunology, 20 (6), 354−361.
1.1.
2005
Sepp, E.; Julge, K.; Mikelsaar, M.; Bjorksten, B. (2005). Intestinal microbiota and immunoglobulin E responses in 5-year-old Estonian children. Clinical & Experimental Allergy, 35 (9), 1141−1146.
1.2.
2005
Songisepp, E.; Kals, J.; Kullisaar, T.; Mändar, R.; Hütt, P.; Zilmer, M.; Mikelsaar, M. (2005). Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutrition Journal, 4 (22), 141−146.
1.2.
2005
Kasenõmm, P.; Piirsoo, A.; Kull, M.; Kull, M. Jr.; Mikelsaar, M. (2005). Selection of indicators for tonsillectomy in adults with recurrent tonsillitis. BMC Ear, Nose and Throat Disorders, 5:7, 1−8. DOI: 10.1186/1472-6815-5-7.
1.2.
2005
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Mikelsaar, M. (2005). Oral microbial ecology in chronic periodontitis and periodontal health. Microbial Ecology in Health and Disease, 17 (3), 146−155.
1.3.
2005
Kasenõmm, P.; Piirsoo, A.; Kull, M; Kull, M.; Mikelsaar, M. (2005). Kroonilise tonsilliidi patogeneesi uuringud kui alus tonsillektoomia objektiivsete kriteeriumite leidmiseks [Studies on pathogenesis of chronic tonsillitis for recovey of objective criteria for tonsillectomia ]. Eesti Arst, 84 (8), 531−541.
3.4.
2005
Hütt, P.; Shchepetova, J.; Lõivukene, K.; Mikelsaar, M. (2005). Determination of antagonistic activities of different probiotics against pathogens. 8th symposium on Lactic Acid Bacteria; Egmond aan Zee, The Netherlands; 28 August - 01 September, 2005.
5.1.
2005
Andreson, H.; Sillakivi, T.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2005). In perforated peptic ulcer patients Helicobacter pylori infection tends to persist. Helicobacter, 10 (5), 481−481.
5.2.
2005
Zilmer, M.; Songisepp, E.; Kullisaar, T.; Zilmer, K.; Mikelsaar, M. (2005). Lactobacillus fermentum: probiotic and health characteristics essential for conception of functional food. 18th International Congress of Nutrition; Durban, South Africa; 19.-23.09.2005.
5.2.
2005
Mikelsaar, M.; Truusalu, K.; Kullisaar, T.; Naaber, P.; Mikelsaar, R.-H.; Zilmer, M. (2005). Effect of probiotic induced antioxidative response in experimental murine typhoid. XI International Congress of Bacteriology and Applied Microbiology; California, USA; July 2005.
5.2.
2005
Kullisaar, T.; Lukman, A.; Zilmer, K.; Vihalemm, T.; Mikelsaar, M.; Zilmer, M. (2005). Probiotic L. fermentum ME-3 may have impact on the rehabilitation quality of elderly stroke patients. 18th International Congress of Nutrition; Durban, South Africa; September 19-23, 2005. , 301.
5.2.
2005
Songisepp, E.; Kals, J.; Hütt, P.; Mändar, R.; Mikelsaar, M. (2005). Impact of the probiotic L. fermentum ME-3 consumption with different formulations and daily doses on the fecal lactoflora, its composition and ME-3 fecal recovery. 8th Symposium on Lactic Acid Bacteria. Book of Abstract: 8th Symposium on Lactic Acid Bacteria; Egmond aan Zee, The Netherlands; 28 August-01 September, 2005.
5.2.
2005
Shehpetova, J.; Truusalu, K.; Sepp, E.; Mikelsaar, M. (2005). Sulfamethoxazole resistance gene in uropathogenic E. coli. 15th European Congress of Clinical Microbiology and Infectious Diseases: ESCMID; Copenhagen, Denmark; 2-5 April 2005. , 404.
5.2.
2005
Hütt, Pirje; Štšepetova, Jelena; Lõivukene, Krista; Mikelsaar, Marika (2005). Probiootikumide antagonistliku aktiivsuse erinevus sõltuvalt kasvukeskkonnast. Eesti Arst, 9, 656−657.
5.2.
2005
Kõll-Klais, P.; Mändar, R.; Smidt, I.; Mikelsaar, M. (2005). Laktobatsillide valik kasutamiseks teise põlvkonna probiootikumidena. Eesti Arst, 9. , 665.
5.2.
2005
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Marcotte, H.; Hammarström, L.; Mikelsaar, M. (2005). Oral lactobacilli in chronic periodontitis: species composition and antimicrobial activity. IADR. , 31.
1.1.
2004
Naaber, P.; Mikelsaar, M. (2004). Interactions between lactobacilli and antibiotic-associated diarrhea. Advances in Applied Microbiology, 54, 231−260.
1.1.
2004
Naaber, P.; Smidt, I.; Stsepetova, J.; Brilene, T.; Annuk, H.; Mikelsaar, M. (2004). Inhibition of Clostridium difficile strains by intestinal Lactobacillus species. Journal of Medical Microbiology, 53 (6), 551−554.
1.1.
2004
Songisepp, E.; Kullisaar, T.; Hutt, P.; Elias, P.; Brilene, T.; Zilmer, M.; Mikelsaar, M. (2004). A new probiotic cheese with antioxidative and antimicrobial activity. Journal of Dairy Science, 87 (7), 2017−2023.
1.1.
2004
Kasenomm, P.; Mesila, I.; Piirsoo, A.; Kull, M.; Mikelsaar, M.; Mikelsaar, RH. (2004). Macroscopic oropharyngeal signs indicating impaired defensive function of palatine tonsils in adults suffering from recurrent tonsillitis. Apmis, 112, 248−256.
1.1.
2004
Maaroos, H.-I.; Andreson, H.; Loivukene, K.; Hutt, P.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2004). The diagnostic value of endoscopy and Helicobacter pylori tests for peptic ulcer patients in late post-treatment setting. BMC Gastroenterology, 4, Art.No. 27.
1.2.
2004
Truusalu, K.; Naaber, P.; Kullisaar, T.; Tamm, H.; Mikelsaar, R.; Zilmer, K.; Rehema, A.; Zilmer, M.; Mikelsaar, M. (2004). The influence of antibacterial and antioxidative probiotic lactobacilli on gut mucosa in a mouse model of Salmonella infection. Microbial Ecology in Health and Disease, 16 (4), 180−187. DOI: 10.1080/08910600410021783.
3.1.
2004
Mikelsaar, M.; Mändar, R.; Sepp, E.; Annuk, H. (2004). Human lactic acid microflora and its role in the welfare of the host. In: Salminen, S.; von Wright, A. (Ed.). Lactic Acid Bacteria (453−506). . New York: Marcel Dekker Inc. (Food science and technology; 139).
5.2.
2004
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2004). Subgingival microbial relations in chronic periodontitis and periodontal health. Microbial Ecology in Health and Disease: SOMED; Helsingör, Denmark; 6-9 May, 2004. Taylor & Francis Ltd.
5.2.
2004
Mikelsaar, R.; Truusalu, K.; Murde, M.; Naaber, P.; Mikelsaar, M. (2004). Probiotic lactobacilli enhance eradication of Salmonella Typhimurium in animal model. Abstr. 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004, Washington D.C.: 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004, Washington D.C.. Amer Soc Microbiology, 61.
5.2.
2004
Mikelsaar, M. (2004). Probiotic lactobacilli vs. Helicobacter pylori. Microbial ecology in health and disease: SOMED, Helsingör, Taani, 6.-9. Mai 2004. , 23.
5.2.
2004
Kõll-Klais, P.; Mändar, R.; Leibur, E.; Mikelsaar, M. (2004). Suuõõne laktobatsillide antagonistlikud omadused parodontiiti põhjustavate patogeenide suhtes. Eesti Arst, 9. , 615.
1.1.
2003
Annuk, H.; Shchepetova, J.; Kullisaar, T.; Songisepp, E.; Zilmer, M.; Mikelsaar, M. (2003). Characterization of intestinal lactobacilli as putative probiotic candidates. Journal of Applied Microbiology, 94 (3), 403−412.
1.1.
2003
Kullisaar, T.; Songisepp, E.; Mikelsaar, M.; Zilmer, K.; Vihalemm, T.; Zilmer, M. (2003). Antioxidative probiotic fermented goats' milk decreases oxidative stress-mediated atherogenicity in human subjects. British Journal Of Nutrition, 90 (2), 449−456.
1.2.
2003
Maaroos, H-I.; Andreson, H.; Lõivukene, K.; Hütt, P.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2003). The diagnostic value of endoscopy and H. pylori tests for peptic ulcer patients in late post-treatment setting. BMC Gastroenterology, 4 (27), 1−6. DOI: 10.1186/1471-230X-4-27.
1.2.
2003
Lõivukene, K.; Kolk, H.; Rägo, T.; Oona, M.; Maaroos, H-I.; Mikelsaar, M. (2003). The gastric ecology of H. pylori positive and negative Children and adults. Microecology and Therapy, 29, 71−78.
1.3.
2003
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2003). Suuõõne mikroobiökoloogia kroonilise parodontiidi puhul. Eesti Arst, 82 (11), 759−767.
1.3.
2003
Sepp, E.; Kõljalg, S.; Truusalu, K.; Štšepetova, L.; Metsvaht, T.; Sau, L.; Jürna, M.; Mägi, H.; Allik, M.; Mikelsaaar, M. (2003). Staphylococcus epidermidis ja Klebsiella pneumoniae - võimalikud hospitaalinfektsioonide tekitajad Eesti lasteintensiivravi osakondades. Eesti Arst, 82 (4), 239−248.
5.1.
2003
Andreson, H.; Maaroos, H.-I.; Mikelsaar, M. (2003). Reliability of noninvasive Helicobacter pylori antigen stool test ImmunoCard STAT! HpSA in peptic ulcer patients after eradicative treatment. Abstracts of the XVIth International Workshop on Gastrointestinal Pathology and Helicobacter. European Helicobacter Study Sroup. Stockholm, September 3-6, 2003: XVIth International Workshop on Gastrointestinal Pathology and Helicobacter. European Helicobacter Study Sroup; Stockholm, Sweden; 3-6 September, 2003. Ed. D.G. Graham. Blackwell Publishing, 490−490. (Helicobacter; 8(4)).
5.2.
2003
Lõivukene, K.; Maaroos, H.; Mikelsaar, M. (2003). Antimicrobial potential of lactobacilli against reference and wild Helicobacter pylori strains. Clinical Microbiology and Infection, S1, 143.
5.2.
2003
Hütt, P.; Songisepp, E.; Kullisaar, T.; Mikelsaar, M.; Zilmer, M. (2003). L. fermentum ME-3 tervist parandava toime uurimine. Eesti Arst, 9, 623.
5.2.
2003
Truusalu, Kai; Sepp, Epp; Naaber, Paul; Murde, Maret; Mikelsaar, Raik-Hiio; Mikelsaar, Marika (2003). Escherichia coli infektsiooni hematogeenne disseminatsioon [Hematogenic dissemination of E. coli infection]. Eesti Arst, 9, 659.
1.1.
2002
Koljalg, S.; Naaber, P.; Mikelsaar, M. (2002). Antibiotic resistance as an indicator of bacterial chlorhexidine susceptibility. Journal of Hospital Infection, 51 (2), 106−113.
1.1.
2002
Kruuner, A.; Pehme, L.; Ghebremichael, S.; Koivula, T.; Hoffner, SE.; Mikelsaar, M. (2002). Use of molecular techniques to distinguish between treatment failure and exogenous reinfection with Mycobacterium tuberculosis. Clinical Infectious Diseases, 35 (2), 146−155.
1.1.
2002
Kullisaar, T.; Zilmer, M.; Mikelsaar, M.; Vihalemm, T.; Annuk, H.; Kairane, C.; Kilk, A. (2002). Two antioxidative lactobacilli strains as promising probiotics. International Journal of Food Microbiology, 72 (3), 215−224.
1.1.
2002
Hynes, SO.; Broutet, N.; Wadstrom, T.; Mikelsaar, M.; O'Toole, PW.; Telford, J.; Engstrand, L.; Kamiya, S.; Mentis, AF.; Moran, AP. (2002). Phenotypic variation of Helicobacter pylori isolates from geographically distinct regions detected by lectin typing. Journal of Clinical Microbiology, 40 (1), 227−232.
1.1.
2002
Andreson, H.; Loivukene, K.; Sillakivi, T.; Maaroos, HI.; Ustav, M.; Peetsalu, A.; Mikelsaar, M. (2002). Association of cagA and vacA genotypes of Helicobacter pylori with gastric diseases in Estonia. Journal of Clinical Microbiology, 40 (1), 298−300.
1.1.
2002
Loivukene, K.; Maaroos, HI.; Kolk, H.; Kull, I.; Labotkin, K.; Mikelsaar, M. (2002). Prevalence of antibiotic resistance of Helicobacter pylori isolates in Estonia during 1995-2000 in comparison to the consumption of antibiotics used in treatment regimens. Clinical Microbiology and Infection, 8 (9), 598−603.
1.1.
2002
Kolk, H.; Maaroos, H-I.; Kull, I.; Labotkin, K.; Lõivukene, K.; Mikelsaar, M. (2002). Open access endoscopy in an epidemiological situation of high prevalence of Helicobacter pylori infection: applicability of the guidelines of the European Society for Primary Care Gastroenterology. Family Practice, 19 (3), 231−235.
1.2.
2002
Kasenõmm, P.; Kull, M.; Mikelsaar, M. (2002). Association between tonsillar core microflora and post-tonsillectomy bacteremia. Microbial Ecology in Health and Disease, 14 (2), 122−127.
1.2.
2002
Stsepetova, E; Sepp, E; Hütt, P; Mikelsaar, M. (2002). Estimation of lactobacill, enterococci and bifidobacteria in fecal samples by quantitative bacteriology and FISH. Microecology and Therapy, 29, 51−59.
1.2.
2002
Mikelsaar, M.; Annuk, H.; Shchepetova, J.; Mändar, R.; Sepp, E.; Björksten, B. (2002). Intestinal lactobacilli of Estonian and Swedish children. Microbial Ecology in Health and Disease, 14, 75−80.
1.2.
2002
Lõivukene, K.; Kolk, H.; Rägo, T.; Oona, M.; Maaroos, H.-I.; Mikelsaar, M. (2002). The gastric ecology of Helicobacter pylori positive and negative children and adults. Microecology and Therapy, 29, 71−78.
5.1.
2002
Andreson, H.; Sillakivi, T.; Peetsalu, A.; Mikelsaar, M. (2002). The dynamics of Helicobacter pylori infection in patients with perforated peptic ulcer. Gut, 51, A18−A18.
5.1.
2002
Koll-Klais, P.; Mandar, R.; Mikelsaar, M.; Leibur, E. (2002). Periodontal microecology in chronic periodontitis patients in an Estonian population. Journal of Dental Research, 81, A206−A206.
5.1.
2002
Kullisaar, T.; Songisepp, E.; Mikelsaar, M.; Zilmer, K.; Vihalemm, T.; Zilmer, M. (2002). Antioxidative and antiatherogenic probiotic lactobacillus ME3. Free Radical Biology and Medicine, 33, S272−S272.
5.2.
2002
Naaber, P.; Tamm, H.; Kullisaar, T.; Zilmer, K.; Rehema, A.; Mikelsaar, R.; Zilmer, M.; Mikelsaar, M. (2002). Laktobatsillide toime salmonelloosi-hiire mudelis. Eesti Arst, 9, 573.
5.2.
2002
Kullisaar, T.; Zilmer, K.; Kaur, S.; Eisen, M.; Rehema, A.; Songisepp, E.; Mikelsaar, M.; Zilmer, M. (2002). Goat milk fermented with antioxidative L.fermentum ME-3 decreases oxidative stress in atopic dermatitis. In: (36−37). 2nd International Symposium on Antioxidants in Nutrition & Therapy: Mechanisms in Physiology-Pathology-Pharmacology; Bali, Indonesia; 2-4 October 2002; abstract book.
5.2.
2002
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2002). Igemetasku mikroobiökoloogia kroonilise parodontiidiga haigetel Eestis. Eesti Arst, 9. , 569.
5.2.
2002
Kõll-Klais, P.; Mändar, R.; Mikelsaar, M.; Leibur, E. (2002). Microecological relations in periodontal sites of chronic periodontitis (CPD) patients. Anaerobe, 3. , 115. (8).
1.1.
2001
Sillakivi, T.; Aro, H.; Ustav, M.; Peetsalu, M.; Peetsalu, A.; Mikelsaar, M. (2001). Diversity of Helicobacter pylori genotypes among Estonian and Russian patients with perforated peptic ulcer, living in Southern Estonia. FEMS Microbiology Letters, 195 (1), 29−33.
1.1.
2001
Mandar, R.; Loivukene, K.; Ehrenberg, A.; Smidt, I.; Raukas, E.; Kask, V.; Mikelsaar, M. (2001). Amniotic fluid microflora in asymptomatic women at mid-gestation. Scandinavian Journal of Infectious Diseases, 33 (1), 60−62.
1.1.
2001
Karki, T.; Truusalu, K.; Vainumae, I.; Mikelsaar, M. (2001). Antibiotic susceptibility patterns of community- and hospital-acquired Staphylococcus aureus and Escherichia coli in Estonia. Scandinavian Journal of Infectious Diseases, 33 (5), 333−338.
1.1.
2001
Mandar, R.; Loivukene, K.; Hutt, P.; Karki, T.; Mikelsaar, M. (2001). Antibacterial susceptibility of intestinal lactobacilli of healthy children. Scandinavian Journal of Infectious Diseases, 33 (5), 344−349.
1.1.
2001
Bjorksten, B.; Sepp, E.; Julge, K.; Voor, T.; Mikelsaar, M. (2001). Allergy development and the intestinal microflora during the first year of life. The Journal of Allergy and Clinical Immunology, 108 (4), 516−520.
1.1.
2001
Annuk, H.; Hynes, SO.; Hirmo, S.; Mikelsaar, M.; Wadstrom, T. (2001). Characterisation and differentiation of lactobacilli by lectin typing. Journal of Medical Microbiology, 50 (12), 1069−1074.
1.1.
2001
Sillakivi, T.; Peetsalu, M.; Mikelsaar, M.; Peetsalu, A. (2001). An attempt at Helicobacter pylori eradication with intravenous clarithromycin in perforated peptic ulcer patients. Scandinavian Journal of Gastroenterology, 36 (10), 1119−1120.
1.2.
2001
Kõljalg, S.; Naaber, P.; Mikelsaar, R.; Mikelsaar, M. (2001). Biocidal effect of protamine and melittin in combination with chlorhexidine. Clinical Microbiology and Infection, 7 (1), 32−34.
1.3.
2001
Sillakivi, T.; Peetsalu, M.; Mikelsaar, M.; Peetsalu, A. (2001). Helicobacter pylori eradikatsioon perforeerunud peptilise haavandiga haigetel [H. pylori eradication in patients with perforated paptic ulcer]. Eesti Arst, 80 (1), 8−11.
5.1.
2001
Mikelsaar, M.; Kullisaar, T.; Zilmer, M. (2001). Antagonistic and antioxidative activity of lactobacilli and survival in oxidative milieu. American Journal of Clinical Nutrition, 73 (2), 495S−495S.
5.2.
2001
Kõll-Klais, P.; Mändar, R.; Naaber, P.; Mikelsaar, M.; Leibur, E. (2001). Parodondi kudede mikroobiökoloogia kroonilise parodontiidiga patsientidel Eestis. Erialane kogumik "Eesti Hambaarstide Päevad 2001": Eesti Hambaarstide Päevad, Tartu, 2001. , 30.
5.2.
2001
Lõivukene, Krista; Aro, Helena; Hütt, Pirje; Kolk, Helgi; Maaroos, Heidi-Ingrid; Mikelsaar, Marika (2001). Erinevate Helicobacter pylori diagnoosivõimaluste efektiivsuse võrdlus. Eesti Arst, 9, 408.
1.1.
2000
Naaber, P.; Smidt, I.; Tamme, K.; Liigant, A.; Tapfer, H.; Mikelsaar, M.; Talvik, R. (2000). Translocation of indigenous microflora in an experimental model of sepsis. Journal of Medical Microbiology, 49 (5), 431−439.
1.1.
2000
Loivukene, K.; Kolk, H.; Maaroos, HI.; Kasenomm, P.; Aro, H.; Ustav, M.; Mikelsaar, M. (2000). Metronidazole and clarithromycin susceptibility and the subtypes of VacA of Helicobacter pylori isolates in Estonia. Scandinavian Journal of Infectious Diseases, 32 (1), 59−62.
1.2.
2000
Tamme, K.; Liigant, A.; Tapfer, H.; Türi, E.; Mikelsaar, M.; Talvik, R. (2000). Multiple organ dissemination of bacteria in experimental sepsis. Papers on Anthropology, 9, 234−240.
1.3.
2000
Lõivukene, K.; Maaroos, H.; Mikelsaar, M.; Kolk, H. (2000). Helicobacter pylori tüvede metronadazool- ja klaritromütsiinitundlikkus Eesti patsientide seas. Eesti Arst, 79 (8), 453−459.
1.3.
2000
Lõivukene, K.; Kolk, H.; Maaroos, H-I.; Mikelsaar, M. (2000). H. pylori tüvede metronidasooli ja klaritromütsiinitundlikkus Eesti patsientide seas. Eesti Arst, 79, 453−459.
3.4.
2000
Karki, Tõnis; Truusalu, Kai; Vainumäe, Inga; Mikelsaar, Marika (2000). Antibiotic resistance of S. aureus and Escherichia coli recovered from inpatients and outpatients in the Estonia. 4th Nordic-Baltic Congress on Infectious Diseases "Prudent use of antibiotics", P−10.
1.1.
1999
Annuk, H.; Hirmo, S.; Turi, E.; Mikelsaar, M.; Arak, E.; Wadstrom, T. (1999). Effect on cell surface hydrophobicity and susceptibility of Helicobacter pylori to medicinal plant extracts. FEMS Microbiology Letters, 172 (1), 41−45.
1.1.
1999
Koljalc, S.; Sults, I.; Raukas, E.; Truu, J.; Ustav, M.; Mikelsaar, M. (1999). Distribution of Acinetobacter baumannii in a neurointensive care unit. Scandinavian Journal of Infectious Diseases, 31 (2), 145−150.
1.1.
1999
Bjorksten, B.; Naaber, P.; Sepp, E.; Mikelsaar, M. (1999). The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clinical & Experimental Allergy, 29 (3), 342−346.
5.1.
1999
Loivukene, K.; Kolk, H.; Mikelsaar, M.; Kasenomm, P.; Ustav, M.; Maaroos, HI. (1999). Comparison of metronidazole susceptibility and vacA subtypes of H-pylori strains in patients with gastritis and peptic ulcer. Gut, 45, A14−A14.
5.2.
1999
Sepp, Epp; Naaber, Paul; Lõivukene, Krista; Kõljalg, Siiri; Voor, Tiia; Björkstén, Bengt; Mikelsaar, Marika (1999). Eesti laste sooletrakti mikrofloora kujunemine esimesel eluaastal. Arstiteaduskonna aastakonverents, 7. oktoober 1999 : teesid, 110−111.
1.1.
1998
Makinen, KK.; Olak, J.; Russak, S.; Saag, M.; Seedre, T.; Vasar, R.; Vihalemm, T.; Mikelsaar, M.; Makinen, PL. (1998). Polyol-combinant saliva stimulants: A 4-month pilot study in young adults. Acta Odontologica Scandinavica, 56 (2), 90−94.
1.1.
1998
Naaber, P.; Mikelsaar, RH.; Salminen, S.; Mikelsaar, M. (1998). Bacterial translocation, intestinal microflora and morphological changes of intestinal mucosa in experimental models of Clostridium difficile infection. Journal of Medical Microbiology, 47 (7), 591−598.
1.2.
1998
Kaila, M.; Isolauri, E.; Sepp, E.; Mikelsaar, M.; Salminen, S. (1998). Fecal recovery of a human Lactobacillus strain (ATCC 53103) during dietary therapy of rotavirus diarrhea in infants. Bioscience and Microflora, 17 (2), 149−151.
1.3.
1998
Mikelsaar, M. (1998). Meditsiinidoktor Andrus-Juhan Voitk [Medical doctor Andrus-Juhan Voitk]. Eesti Arst, 77 (2), 23.
3.1.
1998
Mikelsaar, M.; Mändar, R.; Sepp, E. (1998). Lactic acid microflora in the human microbial ecosystem and its development. In: S. Salminen, A. von Wright (Ed.). Lactic Acid Bacteria: Microbiology and Functional Aspects (Food Science and Technology) (279−342). . New York: Marcel Dekker.
4.2.
1998
Mikelsaar, M.; Mändar, R.(Toim.) (1998). Kliinilise mikrobioloogia käsiraamat. Tallinn: Medicina.
6.2.
1998
Karki, T.; Brilene, T.; Mikelsaar, M. (1998). Praktilised tööd mikrobioloogias I osa. . Tartu: Tartu Ülikooli Kirjastus.
6.2.
1998
Mikelsaar, M.; Karki, T. (1998). Meditsiiniline mikrobioloogia I osa [Medical microbiology]. Tartu: Tartu Ülikooli Kirjastus.
1.1.
1997
Sepp, E.; Julge, K.; Vasar, M.; Naaber, P.; Bjorksten, B.; Mikelsaar, M. (1997). Intestinal microflora of Estonian and Swedish infants. Acta Paediatrica, 86 (9), 956−961.
1.1.
1997
Turi, M.; Turi, E.; Koljalg, S.; Mikelsaar, M. (1997). Influence of aqueous extracts of medicinal plants on surface hydrophobicity of Escherichia coli strains of different origin. Apmis, 105 (12), 956−962.
1.1.
1997
Naaber, P.; Klaus, K.; Sepp, E.; Bjorksten, B.; Mikelsaar, M. (1997). Colonization of infants and hospitalized patients with Clostridium difficile and lactobacilli. Clinical Infectious Diseases, 25, S189−S190.
1.1.
1997
Naaber, P.; Maimets, M.; Mikelsaar, M. (1997). Prevalence and properties of Clostridium difficile in hospitalized patients of Estonia. Reviews in Medical Microbiology, 8, S60−S61.
1.2.
1997
Oona, M.; Rägo, T.; Maaroos, H-I.; Mikelsaar, M.; Lõivukene, K.; Salminen, S.; Korhonen, H. (1997). Helicobacter pylory in children with abdominal complaints: has immune bovine colostrum some influence on gastritis? Alpe Adria Microbiology Journal, 6, 49−57.
1.2.
1997
Tapfer, H.; Liigant, A.; Talvik, R.; Roosar, P.; Hussar, Ü.; Mikelsaar, M.; Simovart, H.-E. (1997). Pathomorphologic responses in experimental sepsis. Papers on Anthropology, VII, 339−350.
1.2.
1997
Ormisson, Anne; Sepp, Epp; Siigur, Urmas; Varendi, Heili; Mikelsaar, Marika (1997). Impact of early life nutrition on growth and intestinal microflora composition in low-birth-weight infants. Scandinavian Journal of Nutrition, 41 (2), 71−74.
1.3.
1997
Sepp, E.; Lõivukene, K.; Naaber, P.; Kermes, K.; Kõljalg, S.; Julge, K.; Vasar, M.; Björksten, B.; Mikelsaar, M. (1997). Tervete ja allergiliste laste mikrofloora erinevused [Differences of intestinal microflora of healthy and allergic children ]. Eesti Rohuteadlane, Lisa, 62−63.
1.1.
1996
Mandar, R.; Mikelsaar, M. (1996). Transmission of mother's microflora to the newborn at birth. Biology of the Neonate, 69 (1), 30−35.
1.1.
1996
Naaber, P.; Lehto, E.; Salminen, S.; Mikelsaar, M. (1996). Inhibition of adhesion of Clostridium difficile to Caco-2 cells. FEMS Immunology & Medical Microbiology, 14 (4), 205−209.
1.1.
1996
Koljalg, S.; VuopioVarkila, J.; Lyytikainen, O.; Mikelsaar, M.; Wadstrom, T. (1996). Cell surface properties of Acinetobacter baumannii. Apmis, 104 (9), 659−665.
1.2.
1996
Mikelsaar, M.; Mändar, R.; Maaroos, H.-I.; Päär, S.; Rägo, T.; Kisand, K.; Aleljung, P.; Wadström, T. (1996). Helicobacter pylori gastritis in children: a clinical, bacteriological, and morphological study. Microecology and Therapy, 22, 44−53.
1.3.
1996
Kõljalg, S.; Kermes, K.; Lõivukene, K.; Naaber, P.; Mikelsaar, M. (1996). Kirurgilisi infektsioone tekitavad mikroorganismid ja nende antibiootikumtundlikkus [Microbes causing surgical infections]. Eesti Arst, lisa, 39−40.
1.3.
1996
Mändar, R.; Mikelsaar, M. (1996). Vaginal microflora during pregnancy. Alpe Adria Microbiology Journal, 5, 41−50.
1.2.
1995
Sepp, E.; Tamm, E.; Torm, S.; Lutsar, I.; Mikelsaar, M.; Salminen, S. (1995). Impact of a lactobacillus probiotic on the faecal microflora in children with shigellosis. Microecology and Therapy, 23, 74−80.
1.2.
1995
Naaber, P.; Mikelsaar, M. (1995). Antibiotic - compromised murine model of C. difficile infection. Microbial Ecology and Therapy, 25, 206−208.
1.2.
1995
Mikelsaar, M.; Sepp, E.; Mändar, R.; Ormisson, A. (1995). Criteria for evaluation of the faecal microflora. Microecology and Therapy, 23, 149−150.
1.2.
1995
Mändar, R.; Saag, H.; Peil, P.; Mikelsaar, M. (1995). Bacterial vaginosis during pregnancy. Microecology and Therapy, 23, 24−31.
1.3.
1994
Naaber, P.; Maimets, M.; Mikelsaar, M. (1994). Clostridium difficile põhjustatud diarröa I. Eesti Arst, 2, 122−124.
1.1.
1993
Sepp, E.; Mikelsaar, M.; Salminen, S. (1993). Effect of administration of lactobacillus-casei strain gg on the gastrointestinal microbiota of newborns. Microbial Ecology in Health and Disease, 6 (6), 309−314.
3.1.
1993
Mikelsaar, M.; Mändar, R. (1993). Development of individual lactic acid microflora in the human microbial ecosystem. S. Salminen; A. von Wright. Lactic Acid Bacteria (237−293). . New York: Marcel Dekker Inc.
1.1.
1990
Kolts, KK.; Mikelsaar, ME.; Maaroos, HIG. (1990). A method for isolation of campylobacter-pylori from gastrointestinal mucosa. Laboratornoe Delo, 2, 44.
1.1.
1990
Mikelsaar, ME.; Siigur, UK.; Lentsner, AA. (1990). Assessment of the fecal microflora quantitative composition. Laboratornoe Delo, 3, 62−66.
1.1.
1989
Tamm, AO.; Siigur, UK.; Mikelsaar, ME. (1989). Antibiotic influence on intestinal microflora and production of metabolites. Antibiotiki i Khimioterapiya, 34 (6), 409−414.
1.1.
1989
Lentsner, AA.; Lentsner, KP.; Mikelsaar, ME.; Turi, ME.; Troshin, AA.; Tark, ER.; Knyazev, VM.; Korolkov, VI.; Lizko, NN.; Petrova, LN. (1989). Species composition of the intestinal lactoflora of healthy rhesus macaques. Zhurnal Mikrobiologii, Epidemiologii i Immunologii, 6, 11−15.
1.1.
1989
Mikelsaar, ME.; Siigur, UK.; Tamm, AO. (1989). Microecological aspects of studies on the effect of antibacterial drugs on intestinal microflora. Antibiotiki i Khimioterapiya, 34 (6), 420−425.
1.2.
1989
Mikelsaar, M.; Sepp, E.; Kasesalu, R.; Kolts, K. (1989). Some Considerations on the Formation of normal Human Microflora during the First Year of Life. Wissenschaftliche Zeitschrift der Ernst-Moritz-Arndt-Universität Greifswald. Med. Reihe, 38, 27−30.
1.1.
1987
Mikelsaar, M.; Turi, M.; Lencner, H.; Kolts, K.; Kirch, R.; Lencner, A. (1987). Interrelations between mucosal and luminal microflora of gastrointestine. Nahrung-Food, 31, 449.
1.1.
1987
Tamm, AO.; Viya, MP.; Mikelsaar, ME.; Siigur, UK. (1987). Metabolites of intestinal microflora and diagnosis of intestine dysbiosis. Antibiotiki i Meditsinskaya Biotekhnologiya, 32 (3), 191−195.
1.1.
1987
Tamm, A.; Siigur, U.; Mikelsaar, M.; Vija, M. (1987). Output of bacterial metabolites as a diagnostic means. Nahrung-Food, 31, 485−492.
1.1.
1987
Lencner, A.; Lencner, H.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Turi, M. (1987). The defense function of the intestinal lactoflora. Nahrung-Food, 31, 405−411.
1.1.
1987
Lenzner, H.; Lenzner, A.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Türi, M.; Levkov, L. (1987). Laktoflora and colonization resistance. Antibiotiki i Meditdinskaya Biotekhnologiya, 32 (3), 173−179.
1.2.
1987
Lenzner, H.; Lenzner, A.; Brilis, V.; Brilene, T.; Mikelsaar, M.; Türi, M. (1987). Zur Abwehrfunktion der Laktoflora des Verdauungstraktes. Die Nahrung, 31, 405−411.
5.1.
1986
Mikelsaar, M. (1986). The possibilities of balanced coexistence in the system organism and its microflora. Endocytobiosis and Cell Research, 3 (3), 350−350.
1.1.
1984
Mikelsaar, ME.; Tjuri, ME.; Valjaots, ME.; Lencner, AA. (1984). Anaerobic lumen and mucosal microflora of the gastrointestinal-tract. Nahrung-Food, 28, 727−733.
1.1.
1984
Lencner, AA.; Mikelsaar, ME.; Tjuri, ME.; Valjaots, ME.; Silov, VM.; Lizko, NN.; Legenkov, VI.; Reznikov, IM. (1984). The quantitative composition of the gut lactoflora before and after cosmic flights of different duration. Nahrung-Food, 28, 607−613.
1.1.
1981
Lentsner, AA.; Lentsner, HP.; Mikelsaar, ME.; Shilov, VM.; Lizko, NN.; Syrykh, GD.; Legenkov, VI. (1981). Examination of the digestive lactoflora of soyuz-13 and salyut-4 crew-members. Kosmicheskaya Biologiya i Aviakosmicheskaya Meditsina, 15 (4), 39−43.
1.1.
1981
Lentsner, AA.; Turi, ME.; Lentsner, HP.; Mikelsaar, ME.; Shilov, VM.; Lizko, NN.; Syrykh, GD. (1981). Study of the antibiotic-sensitivity of digestive lactobacilli of soyuz-13 and salyut-4 crewmembers. Kosmicheskaya Biologiya i Aviakosmicheskaya Meditsina, 15 (4), 36−39.
1.1.
1973
Lentsner, AA.; Shilov, VM.; Lizko, NN.; Mikelsaa, ME. (1973). Study of species composition of intestinal lactobacilli of man during long-term enclosure. Kosmicheskaya Biologiya i Meditsina, 7 (3), 76−80.

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ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
MUUSMVBS17414100-aastased bakterid eestlaste terviseks01.09.201729.02.2020Reet MändarTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut15 000,00 EUR
EMPEMP13Clostridium difficile infektsioon Eestis ja Norras: molekulaarepidemioloogia (k.a. hüpervirulentse tüve 027 esinemine), tüvede omadused ja seedtreakti laktobatsillide koosmõju 01.04.200831.03.2010Epp SeppTartu Ülikool, Arstiteaduskond54 760,98 EUR
ETFETF6782Eakate inimeste seedekulgla mikrofloora, toitumise ja tervise (ateroskleroosi) näitajate seos01.01.200631.12.2009Marika MikelsaarTartu Ülikool; Tartu Ülikool, Arstiteaduskond55 569,40 EUR
SFSF0182555s03Inimese mikroobiökoloogia ja selle mõjutamisvõimalused olulisemate Eestis levinud krooniliste haiguste patogeneesis01.01.200331.12.2007Marika MikelsaarTartu Ülikool, Arstiteaduskond331 190,17 EUR
IUTIUT34-19Inimese mikroobiökoloogiliste häirete mõjustamine erinevate terviseseisundite korral01.01.201531.12.2020Reet MändarTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut624 558,00 EUR
MUUMARMB08019RLACTOBODY - Seedekulgla patogeenide vastaste antikehade fragmentide tekitamine ja üleanne.01.02.200830.01.2011Marika MikelsaarTartu Ülikool334 533,57 EUR
MUUSARMB11189T (3.2.0701.11-0023)Lisaväärtusega piimatoodete innovaatilised teadusuuringud01.01.201231.12.2014Epp SeppTartu Ülikool; Tartu Ülikool, Arstiteaduskond703 139,01 EUR
SFSF0180132s08Mikrofloora tasakaaluhäire kui krooniliste põletike riskifaktor ja selle korrigeerimisvõimalused01.01.200831.12.2013Reet MändarTartu Ülikool, Arstiteaduskond802 264,57 EUR
HLKHLK04-11Mikroobitüvede kollektsioonid01.01.200431.12.2008Marika MikelsaarTartu Ülikool, Arstiteaduskond61 406,63 EUR
MUULMVBS21216Probiootikumide mõju naha mikrobiootale04.01.202130.06.2022Reet MändarTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut47 416,00 EUR
MUUKARMB05042Probiootikumide selektsioon piimatoodete biokvaliteedile ja antiinfektsioossusele01.02.200520.02.2006Marika MikelsaarTartu Ülikool82 957,32 EUR
MUULARMBProbiootilise bakteri lisamine piimavabadesse toodetesse (taimsed piimad) (innovatsiooniosak)15.08.201115.12.2011Marika MikelsaarTartu Ülikool1 984,00 EUR
MUUKARMB05042/1Probiootiliste selekteeritud laktobatsillide sobitamine erinevate piimatoodete tehnoloogilisse protsessi antiinfektsioosse ja immunogeense toime saavutamiseks seedeinfektsioonide vastu15.02.200830.06.2008Marika MikelsaarTartu Ülikool20 259,99 EUR
MUUVARMB04060Rapid introduction of passive immunity against weapons of bioterrorism using transformed GRAS (generally regarded as safe) microorganisms01.07.200430.06.2007Reet MändarTartu Ülikool150 536,47 EUR
MUUKARBK05042/2Teaduspõhiste funktsionaalsete piimatoodete arendus ja toidutööstuse ettevõtete jaoks innovaatiliste biotehnoloogiliste rakenduste/platvormide rakendamine (kasutades mikrobioloogililist, biokeemilist ja kliinilist lähenemist) alaprojekt 2.1. / 101.07.200930.06.2013Marika MikelsaarTartu Ülikool451 065,92 EUR
MUUIARMB07019Uued probiootilised toidulisandid15.01.200730.04.2007Marika MikelsaarTartu Ülikool12 457,91 EUR